Fwd: Centers for Disease Control and Prevention (CDC) Healthcare Professionals' Portal Update

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This is very disturbing to learn, because PCVI is one of two Porcine circovirus Please consult the Vaccines & Immunization website as important information about the Rotarix Vaccine is now available. In the spotlight (What's New):  FDA Update on Rotarix Vaccine Additional information (such as Q & As for parents and providers) will be posted to the site as it becomes available.

88888888888888888888888888888888888888888888888888888888888888888888888888888FDA NEWS RELEASE http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm205625.htm

For Immediate Release: March 22, 2010

Media Inquiries: Burgess, 301-796-4651; shelly.burgess@...

Consumer Inquiries: 888-INFO-FDA

Components of Extraneous Virus Detected in Rotarix Vaccine; No Known

Safety Risk

FDA Recommends Clinicians Temporarily Suspend Use of Vaccine as Agency Learns More8888888888888888888888888888888888888888888888888888888888888888888888888888How many doses of Rotarix have been sold?

http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm205543.htmAbout 68 million doses of Rotarix have been sold worldwide, including

approximately 2.5 million doses in the United States.  With two doses recommended for each child, this means that at most approximately 1 million children have been vaccinated with Rotarix in the United States and approximately 30 million worldwide, with the majority in Latin America.  No unexpected pattern of serious adverse reactions to the vaccine has been reported in any country.88888888888888888888888888888888888888888888888888888888888888888888888888888Journal of Virology, September 2003, p. 9885-9893, Vol. 77, No. 18

0022-538X/03/$08.00+0     DOI: 10.1128/JVI.77.18.9885-9893.2003

New Reporter Gene-Based Replication Assay Reveals Exchangeability of Replication Factors of Porcine Circovirus Types 1 and 2

Annette Mankertz,* Bettina Mueller, Tobias Steinfeldt, Cornelia Schmitt, and Tim Finsterbusch

http://jvi.asm.org/cgi/content/abstract/77/18/9885 " The interchangeability of the replication factors of PCV1 and

PCV2 was examined. The rep not

only able to bind the PCV2 origin but also the origin of PCV1

and vice versa. " 888888888888888888888888888888888888888888888888888888888888888888888888888888

FDA statement: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm205543.htmThere is no evidence at this time that the presence of DNA from PCV1

in Rotarix poses a safety risk to patients.    

So let me get this right...All Rotarix has come from seed stock contaminated with DNA of Porcine Circovirus PCV1 and it was learned in 2003 that PCV2 replicates not only to PCV2 but also to PCV1.

So if child/person has been given Rotarix and PCV1 DNA is now part of their physical make-up, aren't those child/persons now more susceptible thereafter (if exposed) to contract BOTH PCV1 or PCV2 at any time in their lives????

Thanks GlaxoKline!