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Hi Doc

I don't understand why Canada is pushing immigration here when there

isn't any jobs, at least in my province of BC there isn't. While the

government is busy cutting us off of disability to save a few bucks,

they also layed off 30,000 forest workers the same day. I am baffled.

I also have a question for you: I saw my GI doc yesterday....he told me

the peg was approved in Canada but not yet funded under my medical. He

wants me to give the standard combo another try if I can get some

serious sedatives (not valium, I'm used to that) from my PC doc who is

also his brother, by the way. He said my speedy side effects aren't

part of rebetron. Since I have cirrhosis, the chance of clearing the

virus is about 10% with standard combo. Should I wait and see when the

government will fund the peg?? I don't have $50,000 to pay for the

peg. I think he was trying to tell me in so many words that I don't

have much time to waste with my horrid biopsy. Although my liver is

functioning ok now, he explained how it could break down functioning. I

really don't know what to do. If I try the standard combo again, will

that help my liver?? Any thoughts?

Thanks

Carol

Doc wrote:

> And you know what, we get big inserts here in news papers asking

> people to migrate to Canada in big numbers!

> I guess they bring in money that is why.

>

> Dr Sharat Misra MD,DM,FACG

>

> I'm pretty fed up with Canada right now!! My vent for the night.

>

> Huggggggs

> Carol

>

>

>

>

>

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----- Original Message -----

From: Carol

They are calling alomost everybody , even doctors!

>>I don't understand why Canada is pushing immigration here when there

isn't any jobs, at least in my province of BC there isn't. While the

government is busy cutting us off of disability to save a few bucks,

they also layed off 30,000 forest workers the same day. I am baffled.>>>

If you will give me this info again I will be happy to opine.

Viral load

ALT levels

Liver biopsy

Any previous treatment and its outcome

Dr Sharat Misra MD,DM,FACG

>> Although my liver is

functioning ok now, he explained how it could break down functioning. I

really don't know what to do. If I try the standard combo again, will

that help my liver?? Any thoughts?>>

Thanks

Carol

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----- Original Message -----

From: Carol

They are calling alomost everybody , even doctors!

>>I don't understand why Canada is pushing immigration here when there

isn't any jobs, at least in my province of BC there isn't. While the

government is busy cutting us off of disability to save a few bucks,

they also layed off 30,000 forest workers the same day. I am baffled.>>>

If you will give me this info again I will be happy to opine.

Viral load

ALT levels

Liver biopsy

Any previous treatment and its outcome

Dr Sharat Misra MD,DM,FACG

>> Although my liver is

functioning ok now, he explained how it could break down functioning. I

really don't know what to do. If I try the standard combo again, will

that help my liver?? Any thoughts?>>

Thanks

Carol

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Hi Doc

Viral load---they don't do viral loads in Canada anymore since about 8

months ago.

ALT---1 and 1/2 times normal (which is the qualification for treatment

here)

Liver Biopsy:

The core needle biopsy of liver shows marked distortion of normal liver

architecture. There is severe fatty change present. There is

periportal fibrosis with well-established cirrhosis present. The portal

triad shows mild chronic inflammatory cell infiltrate including

lymphocytes and macrophages present. The bile ductules and vessels are

unremarkable. There is no PAS diastase positive granules present.

There is mild parenchymal injury, less than four injured cells

(acidophilic bodies, ballooning degeneration) seen /10 hpf. The central

venules are unremarkable. The iron stain is negative. There is no bile

stasis present. The hepatitis B immuno stain is negative.

I'm genotype 1b. I tried the standard combo....had severe speedy sides,

heart racing, couldn't think, couldn't spell a simple word. Then 3rd

shot, I felt like I'd shot up speed...was having chest pains. I

discontinued until I saw my GI. Although the peg is now approved in

Canada, the funding isn't approved under pharmacare yet. Doctor doesn't

know if they will fund it. He thinks I should try the standard combo

again as long as I can get some serious sedatives from PC doc, who is

his brother, by the way. A month ago he told me my chance of clearing

the virus with cirrhosis was about 10%. I'm wondering if I should just

wait and hope Canada will fund the peg soon....that would raise my odds

quite a bit.

I feel like I'm back in the same boat that already sunk.....don't know

what to do. I trust your opinion Doc....so your input is critical to me

right now. Thank you so much.

The reason Canada wants Doctors to come here is because the pay is the

pits according to the Doctors here....they are going on strike.

Carol

Doc wrote:

>

> ----- Original Message -----

> From: Carol

> They are calling alomost everybody , even doctors!

>

> >>I don't understand why Canada is pushing immigration here when

> there

> isn't any jobs, at least in my province of BC there isn't. While

> the

> government is busy cutting us off of disability to save a few bucks,

>

> they also layed off 30,000 forest workers the same day. I am

> baffled.>>>

>

>

> If you will give me this info again I will be happy to opine.

>

> Viral load

> ALT levels

> Liver biopsy

> Any previous treatment and its outcome

>

> Dr Sharat Misra MD,DM,FACG

>

> >> Although my liver is

> functioning ok now, he explained how it could break down

> functioning. I

> really don't know what to do. If I try the standard combo again,

> will

> that help my liver?? Any thoughts?>>

>

> Thanks

> Carol

>

>

>

>

>

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Thanks Doc...I'll give it another try. But I can't inject everyday,

it's only approved for 3 injections a week. I was on 3mu per shot. Now

to get some sedatives...and develop some +ve thinking.

Thanks

Carol

Doc wrote:

> Hi Carol,

> In a case like yours with cirrhosis , viral load is critical to

> monitor treatment . It seems that " they do not want to do viral

> loads " on patients, there must be plenty of publications from Canada

> with viral loads done .

> Since you never completed combo , you cant be termed as a

> non-responder. Peg is expensive and if they cant do viral loads , I do

> not see them funding Peg.

> Your best bet is to start IFN 3 mu alt day with amantadine or

> ribavirin. If you feel worse after giving it a good try , you can

> always stop.

> HCV Cirrhosis has a HCV clearance rate up to 40 % so one should have a

> +ve attitude.

>

> Dr Sharat Misra MD,DM,FACG

> Re: Doc ( Canada)

>

>

> Hi Doc

>

> Viral load---they don't do viral loads in Canada anymore since about

> 8

> months ago.

> ALT---1 and 1/2 times normal (which is the qualification for

> treatment

> here)

> Liver Biopsy:

> The core needle biopsy of liver shows marked distortion of normal

> liver

> architecture. There is severe fatty change present. There is

> periportal fibrosis with well-established cirrhosis present. The

> portal

> triad shows mild chronic inflammatory cell infiltrate including

> lymphocytes and macrophages present. The bile ductules and vessels

> are

> unremarkable. There is no PAS diastase positive granules present.

> There is mild parenchymal injury, less than four injured cells

> (acidophilic bodies, ballooning degeneration) seen /10 hpf. The

> central

> venules are unremarkable. The iron stain is negative. There is no

> bile

> stasis present. The hepatitis B immuno stain is negative.

>

> I'm genotype 1b. I tried the standard combo....had severe speedy

> sides,

> heart racing, couldn't think, couldn't spell a simple word. Then

> 3rd

> shot, I felt like I'd shot up speed...was having chest pains. I

> discontinued until I saw my GI. Although the peg is now approved in

>

> Canada, the funding isn't approved under pharmacare yet. Doctor

> doesn't

> know if they will fund it. He thinks I should try the standard

> combo

> again as long as I can get some serious sedatives from PC doc, who

> is

> his brother, by the way. A month ago he told me my chance of

> clearing

> the virus with cirrhosis was about 10%. I'm wondering if I should

> just

> wait and hope Canada will fund the peg soon....that would raise my

> odds

> quite a bit.

>

> I feel like I'm back in the same boat that already sunk.....don't

> know

> what to do. I trust your opinion Doc....so your input is critical

> to me

> right now. Thank you so much.

>

> The reason Canada wants Doctors to come here is because the pay is

> the

> pits according to the Doctors here....they are going on strike.

>

>

>

>

>

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Guest guest

Thanks Doc...I'll give it another try. But I can't inject everyday,

it's only approved for 3 injections a week. I was on 3mu per shot. Now

to get some sedatives...and develop some +ve thinking.

Thanks

Carol

Doc wrote:

> Hi Carol,

> In a case like yours with cirrhosis , viral load is critical to

> monitor treatment . It seems that " they do not want to do viral

> loads " on patients, there must be plenty of publications from Canada

> with viral loads done .

> Since you never completed combo , you cant be termed as a

> non-responder. Peg is expensive and if they cant do viral loads , I do

> not see them funding Peg.

> Your best bet is to start IFN 3 mu alt day with amantadine or

> ribavirin. If you feel worse after giving it a good try , you can

> always stop.

> HCV Cirrhosis has a HCV clearance rate up to 40 % so one should have a

> +ve attitude.

>

> Dr Sharat Misra MD,DM,FACG

> Re: Doc ( Canada)

>

>

> Hi Doc

>

> Viral load---they don't do viral loads in Canada anymore since about

> 8

> months ago.

> ALT---1 and 1/2 times normal (which is the qualification for

> treatment

> here)

> Liver Biopsy:

> The core needle biopsy of liver shows marked distortion of normal

> liver

> architecture. There is severe fatty change present. There is

> periportal fibrosis with well-established cirrhosis present. The

> portal

> triad shows mild chronic inflammatory cell infiltrate including

> lymphocytes and macrophages present. The bile ductules and vessels

> are

> unremarkable. There is no PAS diastase positive granules present.

> There is mild parenchymal injury, less than four injured cells

> (acidophilic bodies, ballooning degeneration) seen /10 hpf. The

> central

> venules are unremarkable. The iron stain is negative. There is no

> bile

> stasis present. The hepatitis B immuno stain is negative.

>

> I'm genotype 1b. I tried the standard combo....had severe speedy

> sides,

> heart racing, couldn't think, couldn't spell a simple word. Then

> 3rd

> shot, I felt like I'd shot up speed...was having chest pains. I

> discontinued until I saw my GI. Although the peg is now approved in

>

> Canada, the funding isn't approved under pharmacare yet. Doctor

> doesn't

> know if they will fund it. He thinks I should try the standard

> combo

> again as long as I can get some serious sedatives from PC doc, who

> is

> his brother, by the way. A month ago he told me my chance of

> clearing

> the virus with cirrhosis was about 10%. I'm wondering if I should

> just

> wait and hope Canada will fund the peg soon....that would raise my

> odds

> quite a bit.

>

> I feel like I'm back in the same boat that already sunk.....don't

> know

> what to do. I trust your opinion Doc....so your input is critical

> to me

> right now. Thank you so much.

>

> The reason Canada wants Doctors to come here is because the pay is

> the

> pits according to the Doctors here....they are going on strike.

>

>

>

>

>

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Guest guest

you can take the interferon for as much as your doc will write the script.

I didn't do 3 times a week, I did 3 mu every other day, no break between.

My doc would have prescribed daily.

alley

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you can take the interferon for as much as your doc will write the script.

I didn't do 3 times a week, I did 3 mu every other day, no break between.

My doc would have prescribed daily.

alley

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You had a good Doc, Alley. Mine won't write one for everyday, he

follows the rules....but it's government funded so he has to anyway.

Carol

wrote:

> you can take the interferon for as much as your doc will write the

> script.

>

> I didn't do 3 times a week, I did 3 mu every other day, no break

> between.

> My doc would have prescribed daily.

>

> alley

>

>

>

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Guest guest

You had a good Doc, Alley. Mine won't write one for everyday, he

follows the rules....but it's government funded so he has to anyway.

Carol

wrote:

> you can take the interferon for as much as your doc will write the

> script.

>

> I didn't do 3 times a week, I did 3 mu every other day, no break

> between.

> My doc would have prescribed daily.

>

> alley

>

>

>

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