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Combo or Not to Combo

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Hello everyone,

I have been a lurker on this list for quite some time. I hardly ever post.

Today, I went to see a hepatologist about starting Interferon with

Ribavirin. Depending on the study I get into, this may or may not have

Amantadin with it.

I got blood drawn today. Last April, my PCR was 852,030. I had a test for

genotype just today, and won't know the result for 10 days. My liver biopsy

is a week from today. My ALT was on the high side, just barely within

normal range.

I am most concerned about the sides, because I have to be able to work full

time.

Do most people get so sick they can't work? What has been the experiences of

combo with people on this list? So far, I am not sick.

Edie

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Hi Edie, I have seen you post before. The question

you asked is hard to answer. Everybody reacts

different. I figure even with me restarting it will

be different. I am going to be bumped up from 3 mu to

5 mu of Interferon, in a month when new script is

written. I am wondering if I will experience more

sides, than I did last time. Maybe it might even not

be as bad.........Take Care, Connie

__________________________________________________

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Hi Edie, I have seen you post before. The question

you asked is hard to answer. Everybody reacts

different. I figure even with me restarting it will

be different. I am going to be bumped up from 3 mu to

5 mu of Interferon, in a month when new script is

written. I am wondering if I will experience more

sides, than I did last time. Maybe it might even not

be as bad.........Take Care, Connie

__________________________________________________

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Connie,

Were you able to work in treatment?

Edie

Re: Combo or Not to Combo

> Hi Edie, I have seen you post before. The question

> you asked is hard to answer. Everybody reacts

> different. I figure even with me restarting it will

> be different. I am going to be bumped up from 3 mu to

> 5 mu of Interferon, in a month when new script is

> written. I am wondering if I will experience more

> sides, than I did last time. Maybe it might even not

> be as bad.........Take Care, Connie

>

>

>

> __________________________________________________

>

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Connie,

Were you able to work in treatment?

Edie

Re: Combo or Not to Combo

> Hi Edie, I have seen you post before. The question

> you asked is hard to answer. Everybody reacts

> different. I figure even with me restarting it will

> be different. I am going to be bumped up from 3 mu to

> 5 mu of Interferon, in a month when new script is

> written. I am wondering if I will experience more

> sides, than I did last time. Maybe it might even not

> be as bad.........Take Care, Connie

>

>

>

> __________________________________________________

>

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Hi Edie....

You asked about the sides to treatment and you will get a different

answer from everyone on the list....sides are so individualized.

I've been on the combo for 6-1/2 months and have been very fortunate in

regard to sides. I also was not sick at the time of diagnosis....had my

ex not tracked me down on the net and told me two of his brothers had

died from liver failure related to hep c....and he and his remaining

brother were in treatment, I would never have known I was sick or been

tested. But we shared many things back in the 60s and I guess my past

came back to kick me in the back end.

I didn't have any sides at first....kept waiting for them and looking

for them but nothing. Then about 3 months into treatment I got extremely

irritable and cranky. My liver guy put me on Xanax and that seemed to

help....either that or subconsciously I learned to deal with that

particular side.

I've not missed any work...although I do tend to go to bed earlier. And

now that we are increasing my dosage a tad, I am definitely noticing an

increase in fatigue. But nothing I can't continue to function with.

I live alone (sorta hermit like) with 11 cats so the fear of the sides

was great with me....I had to be able to work to take care of me and the

cats. But as the liver guy told me if you have to work and get sides so

bad you can't work, then just stop the treatment and the sides go away.

So I gave it a shot (no pun intended) and everything has been going

pretty darn well.

I'm genotype 1b, over 50 and a womyn if any of that helps you.

Tatezi

> I got blood drawn today. Last April, my PCR was 852,030. I had a

> test for

> genotype just today, and won't know the result for 10 days. My liver

> biopsy

> is a week from today. My ALT was on the high side, just barely within

>

> normal range.

>

> I am most concerned about the sides, because I have to be able to work

> full

> time.

>

> Do most people get so sick they can't work? What has been the

> experiences of

> combo with people on this list? So far, I am not sick.

>

> Edie

>

>

>

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Hi Edie,

I worked while on Intron A and the combo.

My bosses were very understanding. I was able to cut down to 32 hours a

week when needed. Sometimes I worked less.

I did take the first 10 days off work when I started the combo. My side

effects were minimal at first and I could worked more if I had wanted

to. I did whatever I could to make life easier. Good luck on your

treatment.

hugs,

Judy

http://community.webtv.net/jcmmo/Affirmation

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Hi Edie....

You asked about the sides to treatment and you will get a different

answer from everyone on the list....sides are so individualized.

I've been on the combo for 6-1/2 months and have been very fortunate in

regard to sides. I also was not sick at the time of diagnosis....had my

ex not tracked me down on the net and told me two of his brothers had

died from liver failure related to hep c....and he and his remaining

brother were in treatment, I would never have known I was sick or been

tested. But we shared many things back in the 60s and I guess my past

came back to kick me in the back end.

I didn't have any sides at first....kept waiting for them and looking

for them but nothing. Then about 3 months into treatment I got extremely

irritable and cranky. My liver guy put me on Xanax and that seemed to

help....either that or subconsciously I learned to deal with that

particular side.

I've not missed any work...although I do tend to go to bed earlier. And

now that we are increasing my dosage a tad, I am definitely noticing an

increase in fatigue. But nothing I can't continue to function with.

I live alone (sorta hermit like) with 11 cats so the fear of the sides

was great with me....I had to be able to work to take care of me and the

cats. But as the liver guy told me if you have to work and get sides so

bad you can't work, then just stop the treatment and the sides go away.

So I gave it a shot (no pun intended) and everything has been going

pretty darn well.

I'm genotype 1b, over 50 and a womyn if any of that helps you.

Tatezi

> I got blood drawn today. Last April, my PCR was 852,030. I had a

> test for

> genotype just today, and won't know the result for 10 days. My liver

> biopsy

> is a week from today. My ALT was on the high side, just barely within

>

> normal range.

>

> I am most concerned about the sides, because I have to be able to work

> full

> time.

>

> Do most people get so sick they can't work? What has been the

> experiences of

> combo with people on this list? So far, I am not sick.

>

> Edie

>

>

>

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Hi Edie,

I worked while on Intron A and the combo.

My bosses were very understanding. I was able to cut down to 32 hours a

week when needed. Sometimes I worked less.

I did take the first 10 days off work when I started the combo. My side

effects were minimal at first and I could worked more if I had wanted

to. I did whatever I could to make life easier. Good luck on your

treatment.

hugs,

Judy

http://community.webtv.net/jcmmo/Affirmation

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I was pulled from work by Dr's because of being very

sick (weak and in pain, I had other health things also

and the weekly drawing of 7 to 11, vials of blood

contributed to weakness I think) from the meds and

daily nosebleeds. When short term disability was

close to running out I was terminated. Was a Govt.

(County) job I worked in Public Works, Engineering

Design Div. They have done it to lots of sick people

there. Some have died. I was there almost 10 years,

lacking a few months. It is not a very nice place to

work anymore, it was at one time. But everyone is not

the same Edie and also everytime on meds could be

different..................Take Care, Connie

__________________________________________________

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I was pulled from work by Dr's because of being very

sick (weak and in pain, I had other health things also

and the weekly drawing of 7 to 11, vials of blood

contributed to weakness I think) from the meds and

daily nosebleeds. When short term disability was

close to running out I was terminated. Was a Govt.

(County) job I worked in Public Works, Engineering

Design Div. They have done it to lots of sick people

there. Some have died. I was there almost 10 years,

lacking a few months. It is not a very nice place to

work anymore, it was at one time. But everyone is not

the same Edie and also everytime on meds could be

different..................Take Care, Connie

__________________________________________________

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I was pulled from work by Dr's because of being very

sick (weak and in pain, I had other health things also

and the weekly drawing of 7 to 11, vials of blood

contributed to weakness I think) from the meds and

daily nosebleeds. When short term disability was

close to running out I was terminated. Was a Govt.

(County) job I worked in Public Works, Engineering

Design Div. They have done it to lots of sick people

there. Some have died. I was there almost 10 years,

lacking a few months. It is not a very nice place to

work anymore, it was at one time. But everyone is not

the same Edie and also everytime on meds could be

different..................Take Care, Connie

__________________________________________________

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I was pulled from work by Dr's because of being very

sick (weak and in pain, I had other health things also

and the weekly drawing of 7 to 11, vials of blood

contributed to weakness I think) from the meds and

daily nosebleeds. When short term disability was

close to running out I was terminated. Was a Govt.

(County) job I worked in Public Works, Engineering

Design Div. They have done it to lots of sick people

there. Some have died. I was there almost 10 years,

lacking a few months. It is not a very nice place to

work anymore, it was at one time. But everyone is not

the same Edie and also everytime on meds could be

different..................Take Care, Connie

__________________________________________________

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Hi Edie,

It's nice to hear things seem to FINALLY be moving

along for you!

Side effects can vary a lot from one person to the

next. Some people work full time and never miss a day

of work. Others have a pretty rough time of it. You

will probably hear more from the ones who have had a

bad time simply because many who aren't having any

problems are too busy with their jobs, family, lives,

to be participating in groups like this. During the

year I was on combo there were a few periods when

things were very difficult due to overwhelming

fatigue, but that was mainly due to hypothyroidism

which developed a few months into treatment. Other

than that period I still did pretty much anything I

had done before. However, I DIDN'T work, and could

take naps whenever I wanted. I have heard that

amantadine has some side effects too. My doctor is

talking about putting me on peg + ribavirin +

amantadine too, so that is something I will be looking

into also. Amantadine is another antiviral drug. It

is normally used to treat the flu, I believe. Alone,

it does nothing against the virus. Studies of it in

use with interferon have been contradictory, some

showing a benefit, others showing none. However, some

preliminary studies of it in triple therapy were very

interesting! (I think I have a copy I can post.) How

long will it be after your biopsy before you get the

results? Once you know the results of that, and your

genotype, you'll have a bit more knowledge to base

your decision.

Take care,

Claudine

PS: There is a new support group in San . The

first meeting was Tues., and the meetings will be held

on the second Tue. of each month. At the April

meeting the doctor (I can't remember his name but I

think it started with an L!) who is in charge of the

studies at BAMC is going to be the guest speaker. I

thought you might be interested. Anyone else out

there in the San area?????

C

__________________________________________________

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Hi Edie,

It's nice to hear things seem to FINALLY be moving

along for you!

Side effects can vary a lot from one person to the

next. Some people work full time and never miss a day

of work. Others have a pretty rough time of it. You

will probably hear more from the ones who have had a

bad time simply because many who aren't having any

problems are too busy with their jobs, family, lives,

to be participating in groups like this. During the

year I was on combo there were a few periods when

things were very difficult due to overwhelming

fatigue, but that was mainly due to hypothyroidism

which developed a few months into treatment. Other

than that period I still did pretty much anything I

had done before. However, I DIDN'T work, and could

take naps whenever I wanted. I have heard that

amantadine has some side effects too. My doctor is

talking about putting me on peg + ribavirin +

amantadine too, so that is something I will be looking

into also. Amantadine is another antiviral drug. It

is normally used to treat the flu, I believe. Alone,

it does nothing against the virus. Studies of it in

use with interferon have been contradictory, some

showing a benefit, others showing none. However, some

preliminary studies of it in triple therapy were very

interesting! (I think I have a copy I can post.) How

long will it be after your biopsy before you get the

results? Once you know the results of that, and your

genotype, you'll have a bit more knowledge to base

your decision.

Take care,

Claudine

PS: There is a new support group in San . The

first meeting was Tues., and the meetings will be held

on the second Tue. of each month. At the April

meeting the doctor (I can't remember his name but I

think it started with an L!) who is in charge of the

studies at BAMC is going to be the guest speaker. I

thought you might be interested. Anyone else out

there in the San area?????

C

__________________________________________________

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--- Constance Dickson

<constance_clearwater_florida@...> wrote:

I am going to be bumped up from 3 mu

> to

> 5 mu of Interferon, in a month when new script is

> written. I am wondering if I will experience more

> sides, than I did last time.

Connie,

I did 3 mu, then 6mu, then later down to 5mu, and

my sides were no worse at all with 6mu than with 3mu.

C

__________________________________________________

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--- Constance Dickson

<constance_clearwater_florida@...> wrote:

I am going to be bumped up from 3 mu

> to

> 5 mu of Interferon, in a month when new script is

> written. I am wondering if I will experience more

> sides, than I did last time.

Connie,

I did 3 mu, then 6mu, then later down to 5mu, and

my sides were no worse at all with 6mu than with 3mu.

C

__________________________________________________

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Claudine,

Yes, I am interested in the support group in San . My doctor's name

begins with an " L " , he is sort of a nurdy dude, but that is okay with me.

Tell me where an when.

Edie

Re: Combo or Not to Combo

> Hi Edie,

> It's nice to hear things seem to FINALLY be moving

> along for you!

> Side effects can vary a lot from one person to the

> next. Some people work full time and never miss a day

> of work. Others have a pretty rough time of it. You

> will probably hear more from the ones who have had a

> bad time simply because many who aren't having any

> problems are too busy with their jobs, family, lives,

> to be participating in groups like this. During the

> year I was on combo there were a few periods when

> things were very difficult due to overwhelming

> fatigue, but that was mainly due to hypothyroidism

> which developed a few months into treatment. Other

> than that period I still did pretty much anything I

> had done before. However, I DIDN'T work, and could

> take naps whenever I wanted. I have heard that

> amantadine has some side effects too. My doctor is

> talking about putting me on peg + ribavirin +

> amantadine too, so that is something I will be looking

> into also. Amantadine is another antiviral drug. It

> is normally used to treat the flu, I believe. Alone,

> it does nothing against the virus. Studies of it in

> use with interferon have been contradictory, some

> showing a benefit, others showing none. However, some

> preliminary studies of it in triple therapy were very

> interesting! (I think I have a copy I can post.) How

> long will it be after your biopsy before you get the

> results? Once you know the results of that, and your

> genotype, you'll have a bit more knowledge to base

> your decision.

> Take care,

> Claudine

>

> PS: There is a new support group in San . The

> first meeting was Tues., and the meetings will be held

> on the second Tue. of each month. At the April

> meeting the doctor (I can't remember his name but I

> think it started with an L!) who is in charge of the

> studies at BAMC is going to be the guest speaker. I

> thought you might be interested. Anyone else out

> there in the San area?????

> C

>

>

> __________________________________________________

>

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Claudine,

Yes, I am interested in the support group in San . My doctor's name

begins with an " L " , he is sort of a nurdy dude, but that is okay with me.

Tell me where an when.

Edie

Re: Combo or Not to Combo

> Hi Edie,

> It's nice to hear things seem to FINALLY be moving

> along for you!

> Side effects can vary a lot from one person to the

> next. Some people work full time and never miss a day

> of work. Others have a pretty rough time of it. You

> will probably hear more from the ones who have had a

> bad time simply because many who aren't having any

> problems are too busy with their jobs, family, lives,

> to be participating in groups like this. During the

> year I was on combo there were a few periods when

> things were very difficult due to overwhelming

> fatigue, but that was mainly due to hypothyroidism

> which developed a few months into treatment. Other

> than that period I still did pretty much anything I

> had done before. However, I DIDN'T work, and could

> take naps whenever I wanted. I have heard that

> amantadine has some side effects too. My doctor is

> talking about putting me on peg + ribavirin +

> amantadine too, so that is something I will be looking

> into also. Amantadine is another antiviral drug. It

> is normally used to treat the flu, I believe. Alone,

> it does nothing against the virus. Studies of it in

> use with interferon have been contradictory, some

> showing a benefit, others showing none. However, some

> preliminary studies of it in triple therapy were very

> interesting! (I think I have a copy I can post.) How

> long will it be after your biopsy before you get the

> results? Once you know the results of that, and your

> genotype, you'll have a bit more knowledge to base

> your decision.

> Take care,

> Claudine

>

> PS: There is a new support group in San . The

> first meeting was Tues., and the meetings will be held

> on the second Tue. of each month. At the April

> meeting the doctor (I can't remember his name but I

> think it started with an L!) who is in charge of the

> studies at BAMC is going to be the guest speaker. I

> thought you might be interested. Anyone else out

> there in the San area?????

> C

>

>

> __________________________________________________

>

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<<Anyone else out there in the San area?????>>

Not me I'm in the Dallas Area :) But, do want to know about other Texas

support groups, as I try to keep others updated as well. Thanks :)

Alley/Pat

alleypat@...

http://www.livejournal.com/users/hepatitis_c

http://community.dallasnews.com/dmn/dfwliver

" We were born to make manifest the glory of God within us "

Mandela

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  • 3 weeks later...
Guest guest

In a message dated 2/15/01 11:51:55 PM !!!First Boot!!!,

erodriguez7@... writes:

> Do most people get so sick they can't work? What has been the experiences of

> combo with people on this list? So far, I am not sick.

>

Dear Edie,

It varies from person to person. I've known people who worked through combo.

Some of that depends on what you do for a living. I couldn't, but I had

anadverse reaction to the ribavirin. I could work part time with the

interferon. Hope this helps. Anne

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Guest guest

In a message dated 2/15/01 11:51:55 PM !!!First Boot!!!,

erodriguez7@... writes:

> Do most people get so sick they can't work? What has been the experiences of

> combo with people on this list? So far, I am not sick.

>

Dear Edie,

It varies from person to person. I've known people who worked through combo.

Some of that depends on what you do for a living. I couldn't, but I had

anadverse reaction to the ribavirin. I could work part time with the

interferon. Hope this helps. Anne

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Guest guest

Edie,

Yep, depends on the person and the work really.

I was one of the lucky ones. My symptoms on treatment are very few. Mostly

just fatigue that worsens the longer I'm on treatment, which is to be

expected.

I stopped working at month 6 cuz hubby got a new job with mo mo money.

Unfortunately, he's now laid off :( and I'm way too weak to work right now.

However, I'm toying with some article writing for online hep information.

Researching places that pay for articles.

Most people don't work thru a whole year of treatment. I'm not gonna sugar

coat it. It isn't fun. but it isn't impossible. And it's only temporary. I

mean, how far would you go for a year to rid your life of hep c? I'd go

pretty far :)

Good luck.

/ Alley

alleypat@...

-----------------------------

My ICQ#:12631861<br>

http://members.icq.com/12631861

12631861@...

-------------------------------------------------------

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Guest guest

Edie,

Yep, depends on the person and the work really.

I was one of the lucky ones. My symptoms on treatment are very few. Mostly

just fatigue that worsens the longer I'm on treatment, which is to be

expected.

I stopped working at month 6 cuz hubby got a new job with mo mo money.

Unfortunately, he's now laid off :( and I'm way too weak to work right now.

However, I'm toying with some article writing for online hep information.

Researching places that pay for articles.

Most people don't work thru a whole year of treatment. I'm not gonna sugar

coat it. It isn't fun. but it isn't impossible. And it's only temporary. I

mean, how far would you go for a year to rid your life of hep c? I'd go

pretty far :)

Good luck.

/ Alley

alleypat@...

-----------------------------

My ICQ#:12631861<br>

http://members.icq.com/12631861

12631861@...

-------------------------------------------------------

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