Secret data 'linked' Prozac and violence - Important

[Guest guest]

http://www.theherald.co.uk/news/30682.html

Secret data 'linked' Prozac and violence

ALISON CHIESA December 31 2004

CONFIDENTIAL drug company documents appear to suggest a link between a

popular antidepressant, Prozac, and suicide attempts and violence. They have

been handed to US authorities by the British Medical Journal.

The BMJ received the documents concerning the drug fluoxetine (Prozac) from

an anonymous source and has now turned them over to the US Food and Drug

Administration (FDA).

One of the papers, dated No-vember 1988, reported that in clinical trials

Prozac could cause behavioural disturbances.

The papers reportedly went missing during a lawsuit filed on behalf of

victims of a workplace shooting carried out by ph Wesbecker in

Louisville, Kentucky, in 1989. Wesbecker, who had a long history of

depression and had been put on Prozac a month before the shootings, killed

eight people and injured 12 others before killing himself.

In 1994 some of the relatives of the victims brought a civil suit against

Eli Lilly, the makers of Prozac, alleging the company had known about the

side-effects of the drug, including the fact it might increase violence, for

years.

Although the company won the case it was later forced to admit that it had

made a secret settlement with the pursuers during the trial, making the

verdict invalid.

The documents sent to the BMJ include reviews and memos indicating that Eli

Lilly officials were aware in the 1980s that Prozac had troubling

side-effects and sought to minimise their likely negative effect on

prescribing, according to Jeanne Lenzer, writing in the journal.

The FDA has recently issued a warning that antidepressants can cause

side-effects such as agitation, panic attacks and aggressiveness.

Dr Kapit, the FDA clinical reviewer who approved Prozac, told the

BMJ that he was not given the Lilly data. " These data are very important. If

this report was done by Lilly, or for Lilly, it was their responsibility to

report it to us and to publish it. "

The FDA has agreed to review the documents.

The office of one congressman is reviewing the documents to determine

whether Lilly withheld data. " This is an alarming study that should have

been shared with the public and the FDA from the get-go, not 16 years

later, " Maurice Hinchey said.

In a statement to the BMJ, Lilly said: " Prozac has helped to significantly

improve millions of lives.

" It is one of the most studied drugs in the history of medicine, and has

been prescribed for more than 50 million people worldwide. The safety and

efficacy of Prozac is well studied, well documented and well established. "

[Guest guest]

This my friends is the beginning of the end of Prozac and all the other

me-to SSRI's

and SNRI's that followed it, including Cymbalta. I'm in party mode!!

Jim

http://www.theherald.co.uk/news/30682.html

Secret data 'linked' Prozac and violence

ALISON CHIESA December 31 2004

CONFIDENTIAL drug company documents appear to suggest a link between a

popular antidepressant, Prozac, and suicide attempts and violence. They have

been handed to US authorities by the British Medical Journal.

The BMJ received the documents concerning the drug fluoxetine (Prozac) from

an anonymous source and has now turned them over to the US Food and Drug

Administration (FDA).

One of the papers, dated No-vember 1988, reported that in clinical trials

Prozac could cause behavioural disturbances.

The papers reportedly went missing during a lawsuit filed on behalf of

victims of a workplace shooting carried out by ph Wesbecker in

Louisville, Kentucky, in 1989. Wesbecker, who had a long history of

depression and had been put on Prozac a month before the shootings, killed

eight people and injured 12 others before killing himself.

In 1994 some of the relatives of the victims brought a civil suit against

Eli Lilly, the makers of Prozac, alleging the company had known about the

side-effects of the drug, including the fact it might increase violence, for

years.

Although the company won the case it was later forced to admit that it had

made a secret settlement with the pursuers during the trial, making the

verdict invalid.

The documents sent to the BMJ include reviews and memos indicating that Eli

Lilly officials were aware in the 1980s that Prozac had troubling

side-effects and sought to minimise their likely negative effect on

prescribing, according to Jeanne Lenzer, writing in the journal.

The FDA has recently issued a warning that antidepressants can cause

side-effects such as agitation, panic attacks and aggressiveness.

Dr Kapit, the FDA clinical reviewer who approved Prozac, told the

BMJ that he was not given the Lilly data. " These data are very important. If

this report was done by Lilly, or for Lilly, it was their responsibility to

report it to us and to publish it. "

The FDA has agreed to review the documents.

The office of one congressman is reviewing the documents to determine

whether Lilly withheld data. " This is an alarming study that should have

been shared with the public and the FDA from the get-go, not 16 years

later, " Maurice Hinchey said.

In a statement to the BMJ, Lilly said: " Prozac has helped to significantly

improve millions of lives.

" It is one of the most studied drugs in the history of medicine, and has

been prescribed for more than 50 million people worldwide. The safety and

efficacy of Prozac is well studied, well documented and well established. "

[Guest guest]

Amen

> This my friends is the beginning of the end of Prozac and all the

other

> me-to SSRI's

> and SNRI's that followed it, including Cymbalta. I'm in party

mode!!

>

> Jim

>

>

>

>

> http://www.theherald.co.uk/news/30682.html

>

> Secret data 'linked' Prozac and violence

>

> ALISON CHIESA December 31 2004

>

> CONFIDENTIAL drug company documents appear to suggest a link

between a

> popular antidepressant, Prozac, and suicide attempts and violence.

They have

> been handed to US authorities by the British Medical Journal.

> The BMJ received the documents concerning the drug fluoxetine

(Prozac) from

> an anonymous source and has now turned them over to the US Food

and Drug

> Administration (FDA).

> One of the papers, dated No-vember 1988, reported that in clinical

trials

> Prozac could cause behavioural disturbances.

> The papers reportedly went missing during a lawsuit filed on

behalf of

> victims of a workplace shooting carried out by ph Wesbecker in

> Louisville, Kentucky, in 1989. Wesbecker, who had a long history of

> depression and had been put on Prozac a month before the

shootings, killed

> eight people and injured 12 others before killing himself.

> In 1994 some of the relatives of the victims brought a civil suit

against

> Eli Lilly, the makers of Prozac, alleging the company had known

about the

> side-effects of the drug, including the fact it might increase

violence, for

> years.

> Although the company won the case it was later forced to admit

that it had

> made a secret settlement with the pursuers during the trial,

making the

> verdict invalid.

> The documents sent to the BMJ include reviews and memos indicating

that Eli

> Lilly officials were aware in the 1980s that Prozac had troubling

> side-effects and sought to minimise their likely negative effect on

> prescribing, according to Jeanne Lenzer, writing in the journal.

> The FDA has recently issued a warning that antidepressants can

cause

> side-effects such as agitation, panic attacks and aggressiveness.

> Dr Kapit, the FDA clinical reviewer who approved Prozac,

told the

> BMJ that he was not given the Lilly data. " These data are very

important. If

> this report was done by Lilly, or for Lilly, it was their

responsibility to

> report it to us and to publish it. "

> The FDA has agreed to review the documents.

> The office of one congressman is reviewing the documents to

determine

> whether Lilly withheld data. " This is an alarming study that

should have

> been shared with the public and the FDA from the get-go, not 16

years

> later, " Maurice Hinchey said.

> In a statement to the BMJ, Lilly said: " Prozac has helped to

significantly

> improve millions of lives.

> " It is one of the most studied drugs in the history of medicine,

and has

> been prescribed for more than 50 million people worldwide. The

safety and

> efficacy of Prozac is well studied, well documented and well

established. "

>

>

>

[Guest guest]

Amen

> This my friends is the beginning of the end of Prozac and all the

other

> me-to SSRI's

> and SNRI's that followed it, including Cymbalta. I'm in party

mode!!

>

> Jim

>

>

>

>

> http://www.theherald.co.uk/news/30682.html

>

> Secret data 'linked' Prozac and violence

>

> ALISON CHIESA December 31 2004

>

> CONFIDENTIAL drug company documents appear to suggest a link

between a

> popular antidepressant, Prozac, and suicide attempts and violence.

They have

> been handed to US authorities by the British Medical Journal.

> The BMJ received the documents concerning the drug fluoxetine

(Prozac) from

> an anonymous source and has now turned them over to the US Food

and Drug

> Administration (FDA).

> One of the papers, dated No-vember 1988, reported that in clinical

trials

> Prozac could cause behavioural disturbances.

> The papers reportedly went missing during a lawsuit filed on

behalf of

> victims of a workplace shooting carried out by ph Wesbecker in

> Louisville, Kentucky, in 1989. Wesbecker, who had a long history of

> depression and had been put on Prozac a month before the

shootings, killed

> eight people and injured 12 others before killing himself.

> In 1994 some of the relatives of the victims brought a civil suit

against

> Eli Lilly, the makers of Prozac, alleging the company had known

about the

> side-effects of the drug, including the fact it might increase

violence, for

> years.

> Although the company won the case it was later forced to admit

that it had

> made a secret settlement with the pursuers during the trial,

making the

> verdict invalid.

> The documents sent to the BMJ include reviews and memos indicating

that Eli

> Lilly officials were aware in the 1980s that Prozac had troubling

> side-effects and sought to minimise their likely negative effect on

> prescribing, according to Jeanne Lenzer, writing in the journal.

> The FDA has recently issued a warning that antidepressants can

cause

> side-effects such as agitation, panic attacks and aggressiveness.

> Dr Kapit, the FDA clinical reviewer who approved Prozac,

told the

> BMJ that he was not given the Lilly data. " These data are very

important. If

> this report was done by Lilly, or for Lilly, it was their

responsibility to

> report it to us and to publish it. "

> The FDA has agreed to review the documents.

> The office of one congressman is reviewing the documents to

determine

> whether Lilly withheld data. " This is an alarming study that

should have

> been shared with the public and the FDA from the get-go, not 16

years

> later, " Maurice Hinchey said.

> In a statement to the BMJ, Lilly said: " Prozac has helped to

significantly

> improve millions of lives.

> " It is one of the most studied drugs in the history of medicine,

and has

> been prescribed for more than 50 million people worldwide. The

safety and

> efficacy of Prozac is well studied, well documented and well

established. "

>

>

>