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Caren or others with no energy I still think the NADH is worth as

shot, not everyone may benefit from it or feel the difference the

first time you try it but I can guarantee it is making a big

difference for me, I am able to go to work, work out, stay up late,

etc and still have a clear head and energy, and I am attributing it

to the NADH so I still think it is a good supplement. I am still so

achy in the mornings but usually by afternoon I am ok, so I am going

to the gym after work instead of first thing so that I don't feel so

much pain. Mornings are hard.

I am taking a magnesium supplement now, but after reading e's

post I am wondering if it is a good idea, anyone have any info here

on this?

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> I am taking a magnesium supplement now, but after reading e's

> post I am wondering if it is a good idea, anyone have any info here

> on this?

According to my references, toxic symptoms are RARE as long as the kidneys

are functioning normally. Where kidney function is impaired and magnesium

is being supplemented, toxic symptoms from excess may develop, These would

include slow heart rate, fatigue, low blood pressure, flushing, dry mouth,

muscular weakness, thirst, nausea and vomiting.

Otherwise, I have no qualms about taking supplemental magnesium. Nobody

seems to question the need for calcium--we all need it. It is probablay the

most important mineral you can get. However, magnesium and calcium are

needed together. The recommended ratio of dietary calcium to magnesium is

2:1. So, if you take a calcium supplement, you also need to take magnesium

by half as much.

Patty

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I found the ENADA NADH in a vitamin store here in Denver

called Vitamin Cottage. They will also ship out of

state orders if you don't have a Vitamin Cottage in your

state (I think it is just in Colorado). However, it

really is expensive. I can't remember if it is more

expensive than immunesupport or not. But the 5mg tabs

were $28.95 for 30. If anyone wants the toll free # for

Vitamin Cottage, please let me know.

As for the Mg supplement, there is no doubt that Mg is

very important for our overall well being. However, if

your serum levels are normal, then you should not be

taking a supplement, as Mg has the great potential for

toxicity. Too much Mg can cause weak or absent deep

tendon reflexes, cardiac arrhythmias, hypotension,

circulatory collapse, and respiratory paralysis. In

addition, it interacts with several cardiac meds,

tetracycline, and CNS depressants, including benzos,

pain meds, muscle relaxers, and some antidepressants.

So, I would suggest that before just taking a Mg

supplement, have a serum Mg level drawn and see if your

Mg level is normal or not. If it is normal, then you DO

NOT need to take a supplement.

e

> Caren or others with no energy I still think the NADH is worth as

> shot, not everyone may benefit from it or feel the difference the

> first time you try it but I can guarantee it is making a big

> difference for me, I am able to go to work, work out, stay up late,

> etc and still have a clear head and energy, and I am attributing it

> to the NADH so I still think it is a good supplement. I am still so

> achy in the mornings but usually by afternoon I am ok, so I am going

> to the gym after work instead of first thing so that I don't feel so

> much pain. Mornings are hard.

>

> I am taking a magnesium supplement now, but after reading e's

> post I am wondering if it is a good idea, anyone have any info here

> on this?

>

>

>

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I also need to let you all know that too much calcium is

not good, either. In fact, taking a calcium supplement

can actually worsen osteoarthritis, and can leech

minerals from bones, making them softer.

There is a study going on at the University of Colorado

Health Sciences Center and the results they are getting

are indicating the above. Also, one of my friends is a

pharmacist who monitors studies and she said that there

are several studies being done in the states and Europe

coming to the same conclusions. Again, the studies are

finding that if you eat healthy and get the recommended

serving of each food group, then you should not need a

calcium supplement. However, if you don't get the

recommended servings from all the food groups, then a

calcium supplement is recommended. But you must not go

overboard and assume that more is better. Many people

assume that if one pill is good, 2 is better. Not true,

and this is where people are doing more harm to their

bones than they think. And in fact, my rheumatologist

is now recommending that women not take calcium

supplements, but is giving them well balanced diets to

follow where there are foods with high calcium in them.

While Mg toxicity is not common, it can become much more

common if your serum Mg levels are normal. That is why

it is imperative to have a serum Mg level checked to see

if you truly are deficient or not. It would be rare to

find a doc who will give the okay to take a Mg

supplement if your Mg level is normal. The same with

calcium. You can have serum Ca levels checked as well

to see if your body is deficient or not absorbing the

calcium you eat.

Trust me, I am not trying to start a fight or be

difficult, but these are the facts. And even though, in

the case of Mg toxicity, it is rare, you can still be

receiving too much and not know it. Some of the signs

and symtoms of Mg toxicity are not known until it is too

late. I have seen several cases working in the open

heart ICU where pts come in through the ER and have

vague complaints, and when their Mg level is checked,

they have severe hypermagnesemia. Another example is a

pt who is having some arrhythmias or just not feeling

well. A visual inspection doesn't reveal anything out

of the ordinary, but when Mg levels are checked, the pt

has such severe hypermagnesemia that they could have

died. And this happened to me in ton just a few

wks ago. I had a pt who had her labs drawn at 5am, and

everything was within normal limits, including Mg. 5

hrs later, she had non-specific complaints of weakness.

When I redrew her labs, her Mg came back at 3.2, which

is extremely high. And I had to give her an amp of

calcium to reverse the hypermagnesemia.

So, it is just smart to have your serum levels checked

before taking these supplements, since both Ca and Mg

can have deleterious effects on the heart, lungs,

musculoskeletal system, and nervous system.

e

>

> > I am taking a magnesium supplement now, but after reading e's

> > post I am wondering if it is a good idea, anyone have any info here

> > on this?

>

> According to my references, toxic symptoms are RARE as long as the kidneys

> are functioning normally. Where kidney function is impaired and magnesium

> is being supplemented, toxic symptoms from excess may develop, These would

> include slow heart rate, fatigue, low blood pressure, flushing, dry mouth,

> muscular weakness, thirst, nausea and vomiting.

>

> Otherwise, I have no qualms about taking supplemental magnesium. Nobody

> seems to question the need for calcium--we all need it. It is probablay the

> most important mineral you can get. However, magnesium and calcium are

> needed together. The recommended ratio of dietary calcium to magnesium is

> 2:1. So, if you take a calcium supplement, you also need to take magnesium

> by half as much.

> Patty

>

>

>

>

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As for the Mg supplement, there is no doubt that Mg is

> very important for our overall well being. However, if

> your serum levels are normal, then you should not be

> taking a supplement....

I just wanted to point out that in the two articles that I posted about

magnesium, both stated that serum levels of magnesium are poor indicators of

intracellular magnesium, which is where the problem for those with MCS or

CFS starts. As stated:

" RBC and plasma levels proved to be poor indicators of magnesium status:

2.8% (1/35 positive) and 15% (5/33 positive) respectively. Intravenous

magnesium challenge appeared to be a more accurate assessment of total body

magnesium status (76% positive 39/51). "

" It appeared that serum and red blood cell measurements of magnesium may

not reflect a true state of magnesium depletion unless it is extremely low.

Further, if serum levels fell within the " normal' range, a depleted state

may still be a possibility. This was in agreement with the World Conference

on Magnesium (1985) consensus that the best way to define deficiency was by

magnesium challenge.31 "

" Magnesium may be the most critical single supplement affecting patients

with chronic fatigue syndrome (CFS), since known intracellular magnesium

deficiencies exist in patients with this disorder, according to R.

Cheney, M.D., PhD., and W. Lapp, M.D. "

" ......This might happen, they added, with CFS patients who " crash, " even

though they essentially have normal blood levels of magnesium. "

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I can understand where Mg may be important in the case

of CFS. But CFS is not FMS, which many of us suffer

from as well, and many of us have been told FMS is

what's causing our body aches and pains, not CFS.

However, I am not going to debate the issue of Mg

necessity in cases of CFS, as I am in total agreement

that it can help.

However, I do want to bring to your attention that the

statement made by the World Conference on Mg is rather

outdated, going back to 1985. There have been many

changes in clinical advances and knowledge in the last

16 yrs, so I would question the validity of this

statement at this point in time.

The other point I want to make is that it is rare to see

a Mg challenge done. In fact, I have never seen one

done in 9 yrs of nursing. So, if this is truly the best

way to determine if you are truly low in Mg, then the

majority of docs don't do it. Perhaps it is out of date

now, or it is too expensive and/or most insurance

companies won't cover it.

I am seeing my rheumy on Thurs and will see if he has

any recent articles on Mg and its beneficence to CFS,

FMS, MCS, and other similar conditions. In addition, I

will ask him about the Mg challenge and see what he says

about that.

I just want to provide to the group the latest and most

up to date data. I am in no way, shape or form trying

to be argumentative. I want to educate the women and

provide them with the data they need to make an informed

decision about the supplements and life choices they

make.

e

> As for the Mg supplement, there is no doubt that Mg is

> > very important for our overall well being. However, if

> > your serum levels are normal, then you should not be

> > taking a supplement....

>

> I just wanted to point out that in the two articles that I posted about

> magnesium, both stated that serum levels of magnesium are poor indicators of

> intracellular magnesium, which is where the problem for those with MCS or

> CFS starts. As stated:

>

> " RBC and plasma levels proved to be poor indicators of magnesium status:

> 2.8% (1/35 positive) and 15% (5/33 positive) respectively. Intravenous

> magnesium challenge appeared to be a more accurate assessment of total body

> magnesium status (76% positive 39/51). "

>

> " It appeared that serum and red blood cell measurements of magnesium may

> not reflect a true state of magnesium depletion unless it is extremely low.

> Further, if serum levels fell within the " normal' range, a depleted state

> may still be a possibility. This was in agreement with the World Conference

> on Magnesium (1985) consensus that the best way to define deficiency was by

> magnesium challenge.31 "

>

> " Magnesium may be the most critical single supplement affecting patients

> with chronic fatigue syndrome (CFS), since known intracellular magnesium

> deficiencies exist in patients with this disorder, according to R.

> Cheney, M.D., PhD., and W. Lapp, M.D. "

> " ......This might happen, they added, with CFS patients who " crash, " even

> though they essentially have normal blood levels of magnesium. "

>

>

>

>

>

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Hi e,

Thanks for your comments, they are always appreciated.

I think the best way to educate and inform on this group would be to post

references or articles that support your statements, from credible sources,

when it relates to medical science.

Of course, personal experiences as they relate to breast implants are the

backbone of this support group, and are highly valued.

Thanks again!

Patty

----- Original Message -----

From: <eRene@...>

< >

Sent: Monday, July 16, 2001 6:09 PM

Subject: Re: energy

> I can understand where Mg may be important in the case

> of CFS. But CFS is not FMS, which many of us suffer

> from as well, and many of us have been told FMS is

> what's causing our body aches and pains, not CFS.

> However, I am not going to debate the issue of Mg

> necessity in cases of CFS, as I am in total agreement

> that it can help.

>

> However, I do want to bring to your attention that the

> statement made by the World Conference on Mg is rather

> outdated, going back to 1985. There have been many

> changes in clinical advances and knowledge in the last

> 16 yrs, so I would question the validity of this

> statement at this point in time.

>

> The other point I want to make is that it is rare to see

> a Mg challenge done. In fact, I have never seen one

> done in 9 yrs of nursing. So, if this is truly the best

> way to determine if you are truly low in Mg, then the

> majority of docs don't do it. Perhaps it is out of date

> now, or it is too expensive and/or most insurance

> companies won't cover it.

>

> I am seeing my rheumy on Thurs and will see if he has

> any recent articles on Mg and its beneficence to CFS,

> FMS, MCS, and other similar conditions. In addition, I

> will ask him about the Mg challenge and see what he says

> about that.

>

> I just want to provide to the group the latest and most

> up to date data. I am in no way, shape or form trying

> to be argumentative. I want to educate the women and

> provide them with the data they need to make an informed

> decision about the supplements and life choices they

> make.

>

> e

>

> > As for the Mg supplement, there is no doubt that Mg is

> > > very important for our overall well being. However, if

> > > your serum levels are normal, then you should not be

> > > taking a supplement....

> >

> > I just wanted to point out that in the two articles that I posted about

> > magnesium, both stated that serum levels of magnesium are poor

indicators of

> > intracellular magnesium, which is where the problem for those with MCS

or

> > CFS starts. As stated:

> >

> > " RBC and plasma levels proved to be poor indicators of magnesium status:

> > 2.8% (1/35 positive) and 15% (5/33 positive) respectively. Intravenous

> > magnesium challenge appeared to be a more accurate assessment of total

body

> > magnesium status (76% positive 39/51). "

> >

> > " It appeared that serum and red blood cell measurements of magnesium

may

> > not reflect a true state of magnesium depletion unless it is extremely

low.

> > Further, if serum levels fell within the " normal' range, a depleted

state

> > may still be a possibility. This was in agreement with the World

Conference

> > on Magnesium (1985) consensus that the best way to define deficiency was

by

> > magnesium challenge.31 "

> >

> > " Magnesium may be the most critical single supplement affecting patients

> > with chronic fatigue syndrome (CFS), since known intracellular magnesium

> > deficiencies exist in patients with this disorder, according to R.

> > Cheney, M.D., PhD., and W. Lapp, M.D. "

> > " ......This might happen, they added, with CFS patients who " crash, "

even

> > though they essentially have normal blood levels of magnesium. "

> >

> >

> >

> >

> >

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I will most definately quote from medical journals when

available. However, because I am living in a hotel

until my next travel assignment, I do not have access to

the medical journals that I subscribe to.

On the other hand, I want to say that what I post is

based on knowledge of critical care, cardiac,

neurological, and musculoskeletal nursing. It is based

on the current practices of the physicians and medical

communities that I have worked in. And it is fact based

in the sense that not one physician has strayed from the

documented practices of managing and treating

electrolyte imbalances in the last decade.

And while some of what I post may be based on personal

experiences, the majority of it is based on actual

experiences with patients, physicians, physician

assistants, and other nurses. My statements in regards

to Mg are based on fact as serum Mg is the only reliable

way to determine Mg levels. Again, I want to reinforce

that while doing a Mg challenge may be another accurate

way to determine a Mg level, I have never seen it done,

and have never heard of any physician ordering such a

test. And again, your reference to the article stating

a Mg challenge is the only way to determine a Mg level

is extremely outdated and would have absolutely no

validity in the present. Medical personnel very rarely

accept research data that is more than 1-2 yrs old,

unless it is a proven scientific fact, which must be

proven to have gone through the scientific process.

I believe that what I post on this site is valid, fact

driven, and based on personal experience both as a

patient and as a nurse. I encourage everyone on this

site to read everything, do the research, and then make

an informed decision. I have always encouraged informed

decision making, and always encourage questions and

challenges.

I still think the best guidance I can offer to anyone is

to bring the issues they are concerned with to a

physician they can trust and confide in, get their

opinion and advice, and then ask questions and do the

research.

In the interim, I will see what articles I can find

about Mg, safety and efficacy with Mg supplements,

toxicity, and the Mg challenge vs. serum Mg levels.

e

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