Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 poration is out, that's not it. that takes 1000 volts. everyone's in the dark on hep-c. it won't culture outside the body, and inside it's very hard to measure its effects or where it is. it has never even been seen under electron microscopes. What abt the method of one electrode on the wrist, the other one goes to a pad on the liver? I've been harping on that, but not sure if anyone's even paying attention. the blood carries this, and the liver incubates it. that's the current think. It's only a matter of covering the nest and the infection path, it would seem to keep it sub-clinical. How do the actual numbers look? Are you higher lower or the same as when you started? What abt symptomatically? And any biopsies to compare or just blood samples. bg > > First thing I want to say, is that I have witnessed first hand, the effectiveness of this tech. and I believe it will work to eleminate virus infections. > However, there are still some questions about dosage, timing, and electroporation that have to be ironed out, I think. > I got a steady decrease in the beginning, on the liver cell damage counts. What I considered excellent results, considering that I did almost no other therapy. > Then a steady climb, meaning an increase in damage. > Now the question I have is: is it possible to have electroporation of healthy blood cells, where the electricity allows intact virus to infect the healthy cell, and be ushered into the liver lke a trojan horse? > Is there a threshold of current where current is too high? Or two low? > I haven't given up, but right now, I feel like I'm shooting in the dark. > > BTW, just thought I'd pass this on... > http://bioelectric.ws/eng/electro-news.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 poration is out, that's not it. that takes 1000 volts. everyone's in the dark on hep-c. it won't culture outside the body, and inside it's very hard to measure its effects or where it is. it has never even been seen under electron microscopes. What abt the method of one electrode on the wrist, the other one goes to a pad on the liver? I've been harping on that, but not sure if anyone's even paying attention. the blood carries this, and the liver incubates it. that's the current think. It's only a matter of covering the nest and the infection path, it would seem to keep it sub-clinical. How do the actual numbers look? Are you higher lower or the same as when you started? What abt symptomatically? And any biopsies to compare or just blood samples. bg > > First thing I want to say, is that I have witnessed first hand, the effectiveness of this tech. and I believe it will work to eleminate virus infections. > However, there are still some questions about dosage, timing, and electroporation that have to be ironed out, I think. > I got a steady decrease in the beginning, on the liver cell damage counts. What I considered excellent results, considering that I did almost no other therapy. > Then a steady climb, meaning an increase in damage. > Now the question I have is: is it possible to have electroporation of healthy blood cells, where the electricity allows intact virus to infect the healthy cell, and be ushered into the liver lke a trojan horse? > Is there a threshold of current where current is too high? Or two low? > I haven't given up, but right now, I feel like I'm shooting in the dark. > > BTW, just thought I'd pass this on... > http://bioelectric.ws/eng/electro-news.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 the time factor and morbidity of liver cells may also be interesting. what if the liver cells die off in large numbers 90 or 120 days after electrification while hosting hep-c inside each of them? Does DC set a destruction clock for infected liver cells? With HIV this is so. HIV-Infected CD4's lyse or burst open a week after exposure, suddenly dropping the C4 count which freaks out people. Then they are replaced, the replacements don't get infected, and the count goes up higher than before they dropped. Could something similar be occurring with liver cells? Could this show up as " liver cells damaged " in a blood test? Who knows. bG > > > > First thing I want to say, is that I have witnessed first hand, > the effectiveness of this tech. and I believe it will work to > eleminate virus infections. > > However, there are still some questions about dosage, timing, and > electroporation that have to be ironed out, I think. > > I got a steady decrease in the beginning, on the liver cell > damage counts. What I considered excellent results, considering that > I did almost no other therapy. > > Then a steady climb, meaning an increase in damage. > > Now the question I have is: is it possible to have > electroporation of healthy blood cells, where the electricity allows > intact virus to infect the healthy cell, and be ushered into the > liver lke a trojan horse? > > Is there a threshold of current where current is too high? Or two > low? > > I haven't given up, but right now, I feel like I'm shooting in > the dark. > > > > BTW, just thought I'd pass this on... > > http://bioelectric.ws/eng/electro-news.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 the time factor and morbidity of liver cells may also be interesting. what if the liver cells die off in large numbers 90 or 120 days after electrification while hosting hep-c inside each of them? Does DC set a destruction clock for infected liver cells? With HIV this is so. HIV-Infected CD4's lyse or burst open a week after exposure, suddenly dropping the C4 count which freaks out people. Then they are replaced, the replacements don't get infected, and the count goes up higher than before they dropped. Could something similar be occurring with liver cells? Could this show up as " liver cells damaged " in a blood test? Who knows. bG > > > > First thing I want to say, is that I have witnessed first hand, > the effectiveness of this tech. and I believe it will work to > eleminate virus infections. > > However, there are still some questions about dosage, timing, and > electroporation that have to be ironed out, I think. > > I got a steady decrease in the beginning, on the liver cell > damage counts. What I considered excellent results, considering that > I did almost no other therapy. > > Then a steady climb, meaning an increase in damage. > > Now the question I have is: is it possible to have > electroporation of healthy blood cells, where the electricity allows > intact virus to infect the healthy cell, and be ushered into the > liver lke a trojan horse? > > Is there a threshold of current where current is too high? Or two > low? > > I haven't given up, but right now, I feel like I'm shooting in > the dark. > > > > BTW, just thought I'd pass this on... > > http://bioelectric.ws/eng/electro-news.html Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 My last numbers were 326, a number which alarmed my MD, (normal is 40 or less) the average person with hcv has an average of 80-120, and that's my usual place too,-(if I do nothing) but given my improvement in appearance, and lack of symptoms, I was surprised too. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 14, 2005 Report Share Posted February 14, 2005 My last numbers were 326, a number which alarmed my MD, (normal is 40 or less) the average person with hcv has an average of 80-120, and that's my usual place too,-(if I do nothing) but given my improvement in appearance, and lack of symptoms, I was surprised too. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 there's a medical person asking me about this, who wants to know what was the name of the test used to get these numbers? Was it a liver function test? > My last numbers were 326, a number which alarmed my MD, (normal is 40 or > less) the average person with hcv has an average of 80-120, and that's > my usual place too,-(if I do nothing) but given my improvement in > appearance, and lack of symptoms, I was surprised too. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 there's a medical person asking me about this, who wants to know what was the name of the test used to get these numbers? Was it a liver function test? > My last numbers were 326, a number which alarmed my MD, (normal is 40 or > less) the average person with hcv has an average of 80-120, and that's > my usual place too,-(if I do nothing) but given my improvement in > appearance, and lack of symptoms, I was surprised too. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 The numbers 326 were for sgot, or stpt, I forget which.... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 The numbers 326 were for sgot, or stpt, I forget which.... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 > The numbers 326 were for sgot, or stpt, I forget which.... here's a quote: I recently got lab test results that gave an SGOT level of 143 and SGPT of 309. I have Hep C, but this was my first blood test in the past few years. Are these levels particularly high? And can you tell me if someone can have more than one genotype of the Hepatitis C virus? Thank You, Tim Doctor: They are elevated, but not extremely high and have a consistent pattern of HCV infection. Yes you can have infection with more than one genotype. bG's comment from reading a bit on this: exercising can give falsely high readings. red cell losses give off these enzymes as well as liver damage. Liver damage is one source for elevated levels but not the only source. bG Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 Consistently high numbers mean inflammation and cell death. And can lead to scarring, possibly of the bile duct. People with bile obstruction don't properly process the end result of digestion, just for starters. Long term, it can lead to liver failure; first your bile backs up into the system, poisoning you, which then overburdens the liver, beginning the spiral. The numbers need to be low. Once in awhile, or because of an event or injury; okay, but 30 years is a long time. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 I'm no expert but it seems that they should not be high consistently, I guess I was hoping some factor was present that got overlooked. So far, (and we are certainly not done trying) only a symptomatic relief seems possible with this. Viral load has bounced around, mostly down when used, but then jumps up when stopped. Reduced the load 99 percent in 12 weeks in one case, then stopped it for 3 weeks and it went up to about 1/3 the level before starting 15 weeks earlier, so it didn't stay very low for long. In another case there seems to be no correlation between usage and results in the count, which kept going all over the place. Neither person used it on the liver, just the bloodstream. Sorry this didn't give a better result for you. I'll file it with Hep-c reports. bG > Consistently high numbers mean inflammation and cell death. And can lead > to scarring, possibly of the bile duct. People with bile obstruction > don't properly process the end result of digestion, just for starters. > Long term, it can lead to liver failure; first your bile backs up into > the system, poisoning you, which then overburdens the liver, beginning > the spiral. > The numbers need to be low. Once in awhile, or because of an event or > injury; okay, but 30 years is a long time. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2005 Report Share Posted February 15, 2005 I've just read over the data in your file, Ck, there was a period of normalcy or very near in AST (17-59 normal according to one website I read, yours was 59) about six months ago, if I'm not mistaken. At some point you changed to 2-3ma a day after you were using around 1mA prior. (correct me here if I'm wrong) If you do kill off some of your own cells with too high a current and either poison them from ionization degradation, or otherwise burn them, they give off the same enzyme that damaged liver cells do. If it were me I'd try to duplicate the condition that seemed to work (1mA) and see if it still does? bG > > Consistently high numbers mean inflammation and cell death. And > can lead > > to scarring, possibly of the bile duct. People with bile > obstruction > > don't properly process the end result of digestion, just for > starters. > > Long term, it can lead to liver failure; first your bile backs up > into > > the system, poisoning you, which then overburdens the liver, > beginning > > the spiral. > > The numbers need to be low. Once in awhile, or because of an > event or > > injury; okay, but 30 years is a long time. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2007 Report Share Posted April 6, 2007 Dear Mumbe, As ayoung person eager to intervene to meke development relecvant to those that are marginalised, it is quite encouraging to see that you are interested in measuring effectiveness. I say this because we are now in the era of accountability. When you start activities meant to improve the lot of beneficiaries, you are committing yourself to being accountable to them. The question you ask is pertinent, because often people work with grouops that it may be difficult to prove change using the conventional measurements. However, the lucky thing is that a lot of advancement has come up to try to help implementors measure achievement. These start from being quite cxllear about what you want to do and what chenges yopu want to achieve, and dont forgetr, at the least cost!To beging with consideryour intervention design, then what maesurements and whether they will be effective. Do you want to compare individuals in the population wiyth themselves before and after intervention? Do you want to com[pare intervention population with none intervention population that are fairly simmilar socially? do you want to compare interventuion population with itself? These questions will help you to choose the mosty approapriate INDICATORS and the METHODS of measuring the indicators and testing them for significance of change. For the time being just look up measures of transition such as analysis of variance. look up the limitations. LOOK AT COPARATIVE ANALYSIS FOR SMALL NUMBERS, CHI SQUARED, STUDENT T TEST. Then the more recent methods of measurements of more difficult changes such as Lots quality sample tests (LQST, I think), and measure ment of the Most significant change (MSC) methods the look for those familiar with them to discuss.That is your question is loaded, but it shows your committment to accountability and that is really improtant and commendfable!! Alwar mukithak <mukithak@...> wrote: Dear Friends, I am a reader of this listserv and fortunate to be involved with a small grassroots group in Kibera. Currently I am also a graduate student and looking for ways to carry out research that is relevant and valuable to grassroots organizations providing services to children that are vulnerable especially as a result of HIV/AIDS. I also have an opportunity to develop a baseline survey for an organization. As such I have a couple questions for those involved with organizations providing services to vulnerable children. 1. How do you measure program effectiveness or success? 2. How do you assess whether programs are providing for the social or emotional needs of children? Thank you very much for your time. Mumbe Don't be flakey. Get for Mobile and always stay connected to friends. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2007 Report Share Posted April 6, 2007 Dear Mumbe, As ayoung person eager to intervene to meke development relecvant to those that are marginalised, it is quite encouraging to see that you are interested in measuring effectiveness. I say this because we are now in the era of accountability. When you start activities meant to improve the lot of beneficiaries, you are committing yourself to being accountable to them. The question you ask is pertinent, because often people work with grouops that it may be difficult to prove change using the conventional measurements. However, the lucky thing is that a lot of advancement has come up to try to help implementors measure achievement. These start from being quite cxllear about what you want to do and what chenges yopu want to achieve, and dont forgetr, at the least cost!To beging with consideryour intervention design, then what maesurements and whether they will be effective. Do you want to compare individuals in the population wiyth themselves before and after intervention? Do you want to com[pare intervention population with none intervention population that are fairly simmilar socially? do you want to compare interventuion population with itself? These questions will help you to choose the mosty approapriate INDICATORS and the METHODS of measuring the indicators and testing them for significance of change. For the time being just look up measures of transition such as analysis of variance. look up the limitations. LOOK AT COPARATIVE ANALYSIS FOR SMALL NUMBERS, CHI SQUARED, STUDENT T TEST. Then the more recent methods of measurements of more difficult changes such as Lots quality sample tests (LQST, I think), and measure ment of the Most significant change (MSC) methods the look for those familiar with them to discuss.That is your question is loaded, but it shows your committment to accountability and that is really improtant and commendfable!! Alwar mukithak <mukithak@...> wrote: Dear Friends, I am a reader of this listserv and fortunate to be involved with a small grassroots group in Kibera. Currently I am also a graduate student and looking for ways to carry out research that is relevant and valuable to grassroots organizations providing services to children that are vulnerable especially as a result of HIV/AIDS. I also have an opportunity to develop a baseline survey for an organization. As such I have a couple questions for those involved with organizations providing services to vulnerable children. 1. How do you measure program effectiveness or success? 2. How do you assess whether programs are providing for the social or emotional needs of children? Thank you very much for your time. Mumbe Don't be flakey. Get for Mobile and always stay connected to friends. Quote Link to comment Share on other sites More sharing options...
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