Elavil ??? Reuptake inhibitor?????

[Guest guest]

Elavil IS a Tricyclic antidepressant. It is NOT a SSRI and does not work on

seratonin in any way nor on the reuptake of anything. Considering it as a

selective seratonin reuptake inhibitor could be VERY serious and possibly fatal

if mixed with some drugs that would be ok with SSRI's!!

Drug interactions with selective serotonin reuptake inhibitors, especially with

other psychotropics

http://www.biopsychiatry.com/ssriinteract.htm

Prescrire Int 2001 Feb;10(51):25-31

ABSTRACT

(1) Selective serotonin reuptake inhibitors (SSRIs) are involved in many drug

interactions with potentially serious clinical consequences. (2) These

interactions involve all SSRIs but particularly fluoxetine, which is the

best-studied antidepressant in this family. (3) Because of their long

elimination half-life (particularly fluoxetine) the risk of interactions

persists for several days or even weeks after SSRI withdrawal. (4) Drug

interactions with clinical consequences usually involve combinations of an SSRI

with other psychotropics, especially monoamine oxidase inhibitor (MAOI) and

" tricyclic antidepressants, " clozapine, lithium, methadone, etc. (5) The

clinical consequences of drug interactions with SSRI are either due to

overdosing of the drug combined, or to a serotonin syndrome with neuromuscular

and vegetative (autonomic) symptoms. (6) Interactions with a number of other

drugs have been reported, especially carbamazepine, phenytoin and oral

anticoagulants, with a risk of overdose of these drugs. (7) The risk of

hyponatraemia linked to SSRIs seems to be increased during concomitant treatment

with diuretics.

Elavil IS a " Tricyclic antidepressant " . Do not mix the two.

The main types of antidepressant drugs in use today are:

• Tricyclic antidepressants, such as amitriptyline (Elavil), imipramine

(Tofranil), nortriptyline (Pamelor)

• Selective serotonin reuptake inhibitors (SSRIs or serotonin boosters), such

as fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft)

• Monoamine oxidase inhibitors (MAO inhibitors), such as phenelzine (Nardil),

and tranylcypromine (Parnate)

SOME MEDICATIONS THAT DON'T MIX WELL

http://www.ect.org/tattler/news83.html

THE ANTIDEPRESSANTS known as selective serotonin reuptake inhibitors (SSRIs)

have become popular because they are considered to have fewer side effects and a

much lower risk of overdose than older antidepressants. Nevertheless, SSRIs can

be problematic when combined with other medications.

There could be interactions among SSRIs and these common drugs: --Prozac,

Zoloft: Elavil, Anafranil, Norpramin, Tofranil, Pamelor, Ludiomil, Valium,

Xanax, Versed, Halcion, quinidine, Hismanal, Seldane, Lopressor, Inderol,

Procardia, Adalat, Clozaril, Haldol, Moban, Triavil, Risperdal, Hellaril,

codeine, Percodan, Talwin, lidocaine, Mevacor, tamoxifen, testosterone,

dextromethorphan.