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Hello All,

Aundrea had been home all week from school. She has missed nearly 5

weeks of school this year.

She had a great Thanksgiving and was very active with friends and

family. When reading 's post I was reminded about how

important rest is and how Aundrea tends to go 90 to nothing when she

feels good which is probably why she tends to crash by Sunday night.

Over Thanksgiving she was running, biking, playing all day long.

Since Sunday night her joint pain has been nearly constant. Its in

more joints than usual. Fingers, wrists, knees, ankles and toes.

She doesn't think a joint hurts but when I manipulate it she

goes, " oh I guess that one does hurt " . There is no swelling or

warmth to touch. She is running a fever and hasn't had fevers since

year one of diagnosis. The rash comes and goes but for the most

part has been a non-issue.

So as many of you know we re-started Mtx in July. She was on 15mg

weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

started using phenegan for anti-nausea med. I believe she has had 5

doses on the 20 mg.

So, have I been patient enough. Do I need to give this higher dose

more time before I rule it out and say its not helping? Should we

try increasing to 25mg and see what happens? Is it time to add a

different drug? If so which one? I have always thought that since

aundrea doesn't have swelling then there can't be any joint

destruction taking place...Its more of a pain issue and quality of

life issue...Do you think that is true or can destruction take place

even if you can't see swelling. They have never done x-rays/mri on

Aundrea. Is that a normal procedure to have done and does it give

any useful information as far as treatment.

Ok, I am full of questions today. Sorry about all of that but I am

just not sure where to go from here. I am seriously thinking of

looking into homeschooling or seeing what the options are for

sending her to school part time.

Thanks in advance for any suggestions you may have to offer.

(Aundrea 11 systemic jra/gerd)

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-,

Im so sorry things have not gotten better for Drea, I knew she was

still struggling, shes been Im'ing me the past few days so i knew

she was off school.

To be frank with you, I think you have waited long enough to see if

the increase in MTX will help. I think its time to move onto

something stronger, either enbrel, remicade or kineret. Missing 5

weeks of school is not acceptable, she should not have to do that,

somehting needs to be changed.Have you talked to the school about

homebound schooling for her for awhile. Nicks doctor wrote orders

for this when Nick was missing so much school in the begining

because of the huge fatigue issue he had. They were planning on

sending someone to tutor him at home for a few hours a day. It might

be something to look into for her.

Time to make that call .

let us know what they say.

hugs Helen and (9,systemic)

- In , " sonia1md " <sonia1md@...> wrote:

>

> Hello All,

>

> Aundrea had been home all week from school. She has missed nearly

5

> weeks of school this year.

>

> She had a great Thanksgiving and was very active with friends and

> family. When reading 's post I was reminded about how

> important rest is and how Aundrea tends to go 90 to nothing when

she

> feels good which is probably why she tends to crash by Sunday

night.

>

> Over Thanksgiving she was running, biking, playing all day long.

> Since Sunday night her joint pain has been nearly constant. Its

in

> more joints than usual. Fingers, wrists, knees, ankles and toes.

> She doesn't think a joint hurts but when I manipulate it she

> goes, " oh I guess that one does hurt " . There is no swelling or

> warmth to touch. She is running a fever and hasn't had fevers

since

> year one of diagnosis. The rash comes and goes but for the most

> part has been a non-issue.

>

> So as many of you know we re-started Mtx in July. She was on 15mg

> weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

> started using phenegan for anti-nausea med. I believe she has had

5

> doses on the 20 mg.

>

> So, have I been patient enough. Do I need to give this higher

dose

> more time before I rule it out and say its not helping? Should we

> try increasing to 25mg and see what happens? Is it time to add a

> different drug? If so which one? I have always thought that

since

> aundrea doesn't have swelling then there can't be any joint

> destruction taking place...Its more of a pain issue and quality of

> life issue...Do you think that is true or can destruction take

place

> even if you can't see swelling. They have never done x-rays/mri

on

> Aundrea. Is that a normal procedure to have done and does it give

> any useful information as far as treatment.

>

> Ok, I am full of questions today. Sorry about all of that but I

am

> just not sure where to go from here. I am seriously thinking of

> looking into homeschooling or seeing what the options are for

> sending her to school part time.

>

> Thanks in advance for any suggestions you may have to offer.

>

> (Aundrea 11 systemic jra/gerd)

>

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:

I am so sorry to hear this.

is so right...this is a quality of life issue. You've waited and

waited for the MTX to kick in.

Aundrea is suffering physically, socially, and in her school work.

She could have a bone scan, to see where there is activity in joints. I

think, though, that this is already demonstrated whith what you describe.

Do you want to put her through this? It involves IV contrast.

I would be pushing to move on to another drug, biologic. You've given

everything enough time, and she may be having joint damage already.

I haven't swelled much, and I have damage. Rob as well has not swelled,

but has damage.

I'm rambling here, but had to jump in...

I hope you can find the right combo and get Aundrea back to her old self

again.

Let us know what you decide.

and Rob 17 Spondy

On Wed, 29 Nov 2006 20:09:14 -0000 " sonia1md " <sonia1md@...>

writes:

Hello All,

Aundrea had been home all week from school. She has missed nearly 5

weeks of school this year.

She had a great Thanksgiving and was very active with friends and

family. When reading 's post I was reminded about how

important rest is and how Aundrea tends to go 90 to nothing when she

feels good which is probably why she tends to crash by Sunday night.

Over Thanksgiving she was running, biking, playing all day long.

Since Sunday night her joint pain has been nearly constant. Its in

more joints than usual. Fingers, wrists, knees, ankles and toes.

She doesn't think a joint hurts but when I manipulate it she

goes, " oh I guess that one does hurt " . There is no swelling or

warmth to touch. She is running a fever and hasn't had fevers since

year one of diagnosis. The rash comes and goes but for the most

part has been a non-issue.

So as many of you know we re-started Mtx in July. She was on 15mg

weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

started using phenegan for anti-nausea med. I believe she has had 5

doses on the 20 mg.

So, have I been patient enough. Do I need to give this higher dose

more time before I rule it out and say its not helping? Should we

try increasing to 25mg and see what happens? Is it time to add a

different drug? If so which one? I have always thought that since

aundrea doesn't have swelling then there can't be any joint

destruction taking place...Its more of a pain issue and quality of

life issue...Do you think that is true or can destruction take place

even if you can't see swelling. They have never done x-rays/mri on

Aundrea. Is that a normal procedure to have done and does it give

any useful information as far as treatment.

Ok, I am full of questions today. Sorry about all of that but I am

just not sure where to go from here. I am seriously thinking of

looking into homeschooling or seeing what the options are for

sending her to school part time.

Thanks in advance for any suggestions you may have to offer.

(Aundrea 11 systemic jra/gerd)

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HI :

You know from the email I sent you earlier that you and Drea have been in my

thoughts today. I too think its time to try something more for her. She has

been struggling for so long. I really don't have any other advice since we

aren't on any of the meds most of the kids on the list are.

Please know I am sending you prayers, happy thoughts & cyber hugs!!! Please

let me know what you find out. I would think your school district could

accommodate home tutors for her. I would check into that first. That way when

you do get her pain under control, she can easily get right back into school

without a lot of hassle.

Beth

sonia1md <sonia1md@...> wrote:

Hello All,

Aundrea had been home all week from school. She has missed nearly 5

weeks of school this year.

She had a great Thanksgiving and was very active with friends and

family. When reading 's post I was reminded about how

important rest is and how Aundrea tends to go 90 to nothing when she

feels good which is probably why she tends to crash by Sunday night.

Over Thanksgiving she was running, biking, playing all day long.

Since Sunday night her joint pain has been nearly constant. Its in

more joints than usual. Fingers, wrists, knees, ankles and toes.

She doesn't think a joint hurts but when I manipulate it she

goes, " oh I guess that one does hurt " . There is no swelling or

warmth to touch. She is running a fever and hasn't had fevers since

year one of diagnosis. The rash comes and goes but for the most

part has been a non-issue.

So as many of you know we re-started Mtx in July. She was on 15mg

weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

started using phenegan for anti-nausea med. I believe she has had 5

doses on the 20 mg.

So, have I been patient enough. Do I need to give this higher dose

more time before I rule it out and say its not helping? Should we

try increasing to 25mg and see what happens? Is it time to add a

different drug? If so which one? I have always thought that since

aundrea doesn't have swelling then there can't be any joint

destruction taking place...Its more of a pain issue and quality of

life issue...Do you think that is true or can destruction take place

even if you can't see swelling. They have never done x-rays/mri on

Aundrea. Is that a normal procedure to have done and does it give

any useful information as far as treatment.

Ok, I am full of questions today. Sorry about all of that but I am

just not sure where to go from here. I am seriously thinking of

looking into homeschooling or seeing what the options are for

sending her to school part time.

Thanks in advance for any suggestions you may have to offer.

(Aundrea 11 systemic jra/gerd)

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,

I am sorry to hear of Aundrea's struggles. Call your rheumy and let him/her

know how things are going. Demand an increase/addition of meds. No, you don't

want to go there but she needs to be in better condition than this. Second,

because she tends to use up all her energy on the weekend having fun and then

have nothing for school etc perhaps you can find a counselor or pain management

place for her to work with so she can learn that yes it is good to have fun but

to pace herself for school. Homeschooling can help but unfortunately if she

wants to go to college she is going to have to learn pacing to let her do so.

They do accomodate to an extent but you have to go everyday to make it. I don't

mean this to seem harsh just that it will help her to deal with the illness if

it continues as she gets older. I hope your rheumy can give you some good

suggestions. It seems like they are very slow in increasing meds. We just tend

to go full scale moves. With the mtx it was a weekly

or biweekly increase. She is big enough now that she shouldn't have to go with

such baby steps it seems.

e

sonia1md <sonia1md@...> wrote:

Hello All,

Aundrea had been home all week from school. She has missed nearly 5

weeks of school this year.

She had a great Thanksgiving and was very active with friends and

family. When reading 's post I was reminded about how

important rest is and how Aundrea tends to go 90 to nothing when she

feels good which is probably why she tends to crash by Sunday night.

Over Thanksgiving she was running, biking, playing all day long.

Since Sunday night her joint pain has been nearly constant. Its in

more joints than usual. Fingers, wrists, knees, ankles and toes.

She doesn't think a joint hurts but when I manipulate it she

goes, " oh I guess that one does hurt " . There is no swelling or

warmth to touch. She is running a fever and hasn't had fevers since

year one of diagnosis. The rash comes and goes but for the most

part has been a non-issue.

So as many of you know we re-started Mtx in July. She was on 15mg

weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

started using phenegan for anti-nausea med. I believe she has had 5

doses on the 20 mg.

So, have I been patient enough. Do I need to give this higher dose

more time before I rule it out and say its not helping? Should we

try increasing to 25mg and see what happens? Is it time to add a

different drug? If so which one? I have always thought that since

aundrea doesn't have swelling then there can't be any joint

destruction taking place...Its more of a pain issue and quality of

life issue...Do you think that is true or can destruction take place

even if you can't see swelling. They have never done x-rays/mri on

Aundrea. Is that a normal procedure to have done and does it give

any useful information as far as treatment.

Ok, I am full of questions today. Sorry about all of that but I am

just not sure where to go from here. I am seriously thinking of

looking into homeschooling or seeing what the options are for

sending her to school part time.

Thanks in advance for any suggestions you may have to offer.

(Aundrea 11 systemic jra/gerd)

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Hello Everyone,

Thank you all for your responses. I took time to read thru them and

showed them to my husband as we contemplatd what to do next.

I spoke with Aundrea's rheumy this morning. He started out with the

suggestion of steroids while waiting on mtx to kick in. Prednisone

is absolutely my last resort. Aundrea just does terrible with the

side effects of mood swings. He then suggested adding ibuprofen.

Considering we have tried this twice and each time came away with

severe gerd that didn't sound to good to me...she is finally getting

over gerd and i am very glad of that.

next suggestion was limbrel. You need a dr. script for it but its

considered " natural " and is used as a replacement for cox 2

inhibitors. Anyone heard of this before? He orderd 500mg 2 times

daily. We will try it for 2 weeks. He mentioned enbrel. He is

concerned about the increased risk it poses for valley fever, tb,

respitory infections and bacterial infections.

I met with the school counselor today..She said that if aundrea's

dr. wrote a script saying it was likely that she would miss 3 months

of school during the year then she would qualify for a home bound

tutor. She has already missed 5 weeks. The problem is that there is

only 1 home bound teacher for the entire district so its doubtful we

would get much help there.

Another option we are looking into is sending her for 1/2 days. She

could go at 11 and be done by 2 and just attend core classes but

still be considered full-time and get credit.

On a bright note Aundrea is feeling really good today. Last night

her fingers were so stiff she couldn't even bend them and this

morning she is doing awesome. We have had a cold front come thru so

perhaps that intesified her problems.

I will let ya all know how things go with limbrel. and if anyone

else has experience with it let me know what you thought of it.

Thanks again for everything. You guys mean so much to me and your

suggestions are very valuable to me.

Blessings,

sonia (aundrea 11 systemic jra/gerd)-

In , " sonia1md " <sonia1md@...> wrote:

>

> Hello All,

>

> Aundrea had been home all week from school. She has missed nearly

5

> weeks of school this year.

>

> She had a great Thanksgiving and was very active with friends and

> family. When reading 's post I was reminded about how

> important rest is and how Aundrea tends to go 90 to nothing when

she

> feels good which is probably why she tends to crash by Sunday

night.

>

> Over Thanksgiving she was running, biking, playing all day long.

> Since Sunday night her joint pain has been nearly constant. Its

in

> more joints than usual. Fingers, wrists, knees, ankles and toes.

> She doesn't think a joint hurts but when I manipulate it she

> goes, " oh I guess that one does hurt " . There is no swelling or

> warmth to touch. She is running a fever and hasn't had fevers

since

> year one of diagnosis. The rash comes and goes but for the most

> part has been a non-issue.

>

> So as many of you know we re-started Mtx in July. She was on 15mg

> weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

> started using phenegan for anti-nausea med. I believe she has had

5

> doses on the 20 mg.

>

> So, have I been patient enough. Do I need to give this higher

dose

> more time before I rule it out and say its not helping? Should we

> try increasing to 25mg and see what happens? Is it time to add a

> different drug? If so which one? I have always thought that

since

> aundrea doesn't have swelling then there can't be any joint

> destruction taking place...Its more of a pain issue and quality of

> life issue...Do you think that is true or can destruction take

place

> even if you can't see swelling. They have never done x-rays/mri

on

> Aundrea. Is that a normal procedure to have done and does it give

> any useful information as far as treatment.

>

> Ok, I am full of questions today. Sorry about all of that but I

am

> just not sure where to go from here. I am seriously thinking of

> looking into homeschooling or seeing what the options are for

> sending her to school part time.

>

> Thanks in advance for any suggestions you may have to offer.

>

> (Aundrea 11 systemic jra/gerd)

>

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Hi ,

I haven't been around much lately as I have been busy with a new

job. I am so sorry that Aundrea is still having problems. I think

the last time I checked in things were looking up for her. I really

hope the limbrel helps her a great deal. My son is in fourth grade

and I know how hard it is to miss even at that age.

was on Enbrel for almost two years. She was fairly healthy,

except in the fall when cold season started she had constant sinus

infections from fall to spring. However, it was only on Enbrel that

she enjoyed a 10 month medicated remission free of all jra

symptoms. She is on Humira now (and has been since February) and

has not had any sinus infections at all. She has had strep a couple

of times that cleared up with Amoxicillan.

Hopefully the limbrel will help and Aundrea will feel better enough

to go to school.

Take care.

Sophie

's mom, age 6, systemic jra

> >

> > Hello All,

> >

> > Aundrea had been home all week from school. She has missed

nearly

> 5

> > weeks of school this year.

> >

> > She had a great Thanksgiving and was very active with friends

and

> > family. When reading 's post I was reminded about how

> > important rest is and how Aundrea tends to go 90 to nothing when

> she

> > feels good which is probably why she tends to crash by Sunday

> night.

> >

> > Over Thanksgiving she was running, biking, playing all day

long.

> > Since Sunday night her joint pain has been nearly constant. Its

> in

> > more joints than usual. Fingers, wrists, knees, ankles and

toes.

> > She doesn't think a joint hurts but when I manipulate it she

> > goes, " oh I guess that one does hurt " . There is no swelling or

> > warmth to touch. She is running a fever and hasn't had fevers

> since

> > year one of diagnosis. The rash comes and goes but for the most

> > part has been a non-issue.

> >

> > So as many of you know we re-started Mtx in July. She was on

15mg

> > weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

> > started using phenegan for anti-nausea med. I believe she has

had

> 5

> > doses on the 20 mg.

> >

> > So, have I been patient enough. Do I need to give this higher

> dose

> > more time before I rule it out and say its not helping? Should

we

> > try increasing to 25mg and see what happens? Is it time to add

a

> > different drug? If so which one? I have always thought that

> since

> > aundrea doesn't have swelling then there can't be any joint

> > destruction taking place...Its more of a pain issue and quality

of

> > life issue...Do you think that is true or can destruction take

> place

> > even if you can't see swelling. They have never done x-rays/mri

> on

> > Aundrea. Is that a normal procedure to have done and does it

give

> > any useful information as far as treatment.

> >

> > Ok, I am full of questions today. Sorry about all of that but I

> am

> > just not sure where to go from here. I am seriously thinking of

> > looking into homeschooling or seeing what the options are for

> > sending her to school part time.

> >

> > Thanks in advance for any suggestions you may have to offer.

> >

> > (Aundrea 11 systemic jra/gerd)

> >

>

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Hi Sophie,

I am glad to hear that is doing well with Humira. It seems

to be a promsing drug for many.

I hope that limbrel will do the trick for drea. I definately think

its worth attempting.

If it doesn't work then we may have to discuss the option again of

enbrel. In az. there is a risk of valley fever which is a problem

in Arizona. My cuz is on enbrel for JRA and they have done testing

on her to see if she has valley fever. She had to go off enbrel

which has really caused her to have a major flare. People with

compromsied immune systems can struggle for years or longer with

side effects of valley fever among which are lung infections, body

aches, and extreme fatigue.

I think when we lived in Illinois I would have been more inclined to

try enbrel sooner. Here in Az I wonder if a different biologic

might be a better choice. I guess I would like to know the stats on

how many enbrel users have contracted valley fever.

Well, anyway we will see how things go with limbrel and maybe that

will be all she needs. :-)

Thanks for checking in..it was good to hear from you!

(Aundrea 11 systemic jra/gerd)

> > >

> > > Hello All,

> > >

> > > Aundrea had been home all week from school. She has missed

> nearly

> > 5

> > > weeks of school this year.

> > >

> > > She had a great Thanksgiving and was very active with friends

> and

> > > family. When reading 's post I was reminded about how

> > > important rest is and how Aundrea tends to go 90 to nothing

when

> > she

> > > feels good which is probably why she tends to crash by Sunday

> > night.

> > >

> > > Over Thanksgiving she was running, biking, playing all day

> long.

> > > Since Sunday night her joint pain has been nearly constant.

Its

> > in

> > > more joints than usual. Fingers, wrists, knees, ankles and

> toes.

> > > She doesn't think a joint hurts but when I manipulate it she

> > > goes, " oh I guess that one does hurt " . There is no swelling

or

> > > warmth to touch. She is running a fever and hasn't had fevers

> > since

> > > year one of diagnosis. The rash comes and goes but for the

most

> > > part has been a non-issue.

> > >

> > > So as many of you know we re-started Mtx in July. She was on

> 15mg

> > > weekly sub Q. On Oct 21 we increased MTX to 20 mg weekly and

> > > started using phenegan for anti-nausea med. I believe she has

> had

> > 5

> > > doses on the 20 mg.

> > >

> > > So, have I been patient enough. Do I need to give this higher

> > dose

> > > more time before I rule it out and say its not helping?

Should

> we

> > > try increasing to 25mg and see what happens? Is it time to

add

> a

> > > different drug? If so which one? I have always thought that

> > since

> > > aundrea doesn't have swelling then there can't be any joint

> > > destruction taking place...Its more of a pain issue and

quality

> of

> > > life issue...Do you think that is true or can destruction take

> > place

> > > even if you can't see swelling. They have never done x-

rays/mri

> > on

> > > Aundrea. Is that a normal procedure to have done and does it

> give

> > > any useful information as far as treatment.

> > >

> > > Ok, I am full of questions today. Sorry about all of that but

I

> > am

> > > just not sure where to go from here. I am seriously thinking

of

> > > looking into homeschooling or seeing what the options are for

> > > sending her to school part time.

> > >

> > > Thanks in advance for any suggestions you may have to offer.

> > >

> > > (Aundrea 11 systemic jra/gerd)

> > >

> >

>

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