Nasal Septal Perforation: A Novel Clinical Manifestation of Systemic Juvenile Idiopathic Arthritis/Adult Onset Still's Disease

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Case Report

Nasal Septal Perforation: A Novel Clinical Manifestation of Systemic

Juvenile Idiopathic Arthritis/Adult Onset Still's Disease

(J Rheumatol 2005;32:2429-31)

http://www.jrheum.com/abstracts/abstracts05/2429.html

TADEJ AVCIN, EARL D. SILVERMAN, VITO FORTE, and RAYFEL SCHNEIDER

ABSTRACT.

Nasal septal perforation has been well recognized in patients with various

rheumatic diseases. To our knowledge, this condition has not been reported

in children with systemic juvenile idiopathic arthritis (SJIA) or patients

with adult onset Still's disease (AOSD). We describe 3 patients with

persistent SJIA/AOSD who developed nasal septal perforation during the

course of their disease. As illustrated by these cases, nasal septal

perforation may develop as a rare complication of SJIA/AOSD and can be

considered as part of the clinical spectrum of the disease. In one case the

nasal septal perforation was associated with vasculitis.

From the Division of Rheumatology and Department of Otolaryngology, The

Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

T. Avcin, MD, PhD, Clinical Fellow, Division of Rheumatology; E.D.

Silverman, MD, FRCPC, Professor of Pediatrics and Immunology, Division of

Rheumatology; V. Forte, MD, FRCSC, Associate Professor of Otolaryngology,

Department of Otolaryngology; R. Schneider, MBBCh, FRCPC, Associate

Professor of Pediatrics, Head, Division of Rheumatology.

Address reprint requests to Dr. R. Schneider, Division of Rheumatology, The

Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8.

E-mail: rayfel.schneider@...