Guest guest Posted January 11, 2006 Report Share Posted January 11, 2006 In a message dated 1/11/2006 12:44:16 PM Eastern Standard Time, janel@... writes: For full text pdf go to: http://www.thorne.com/altmedrev/.fulltext/10/4/326.pdf Altern Med Rev. 2005 Dec;10(4):326-336. Related Articles, Links Melatonin - Monograph. [No authors listed] Melatonin, the primary hormone of the pineal gland, acts as a powerful " chronobiotic, " maintaining normal circadian rhythms. In patients with sleep disorders and altered circadian rhythms, such as occur in jet lag, night shift work, and various neuropsychiatric disorders, oral administration of melatonin can provide the necessary resynchronization of those cycles, at dosages ranging from 0.3 to 8 mg. Synthesis of melatonin from the amino acid tryptophan is decreased by exposure to magnetic fields and by the aging process. Melatonin is a potent scavenger of free radicals and exerts direct inhibition of cancer growth. Various cancer types have been shown to be responsive to oral melatonin (10-50 mg daily), including breast cancer, non-small-cell lung cancer, metastatic renal cell carcinoma, hepatocellular carcinoma, and brain metastases from solid tumors. Melatonin has also been reported to lower LDL- and total cholesterol levels. Abnormally low melatonin levels have been theorized to be a factor in multiple sclerosis, coronary heart disease, epilepsy, and postmenopausal osteoporosis. These reports, while preliminary, serve to further illustrate the wide range of potential effects exerted by melatonin. PMID: 16366741 [PubMed - as supplied by publisher] mjh " The Basil Book " http://foxhillfarm.us/FireBasil/ Quote Link to comment Share on other sites More sharing options...
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