Re: Systemic Rash / Naproxyn / Joint Destruction

[Guest guest]

Hi ,

Yes, you are correct about Naproxyn sometimes having a tendency to

affect fair-skinned children in the ways that you describe. I've read

messages from other parents stating exactly that. As for your other

question, regarding the need to worry about the joint destruction which

can occur during periods of inflammation, the rate of joint destruction

varies greatly from one case to another. It's an area of much intense

research but as of right now, it's still really difficult to determine

whose arthritis will progress rapidly and cause early joint damage and

who will have a more mild case. Most doctors would probably eagerly

welcome a simple method of determining this, using markers that could be

found through blood testing, for instance. Instead, they have to decide

using other methods which cases will receive a strong, aggressive,

approach and which will receive a step-up approach (trying NSAIDs alone

first, and then stepping up to the stronger meds gradually, depending

upon response).

Joint pain, most times, is due to underlying inflammation. Some people

believe that the rashes, too, are indicative of inflammation ... of the

skin. Ask about your daughter's C reactive protein and SED rates next

time she has labs done. Those are some of the markers they use to gauge

inflammatory arthritis activity, although they're not foolproof.

Aloha,

Georgina

sonia dykhuizen wrote:

>

> Hi Georgina,

> Thanks for your post, its always helpful to see others past experiences

> with

> this disease.

> Aundrea gets about 4 different types of rashes. The one that you

mentioned

> that Josh got is one that Aundrea is getting now. Their pink and

mishaped

> sizes, migratory, and they are more noticeable upon first thing in the

> morning

> and again by later afternoon.

> Another rash that she has had a couple of times is a small patch of skin

> that

> has little pink dots and is very itchy.

> The rash that she develops during 2 major flares with the fevers was

a body

> wide rash with water blisters that itched and flaked off.

> And finally she has a rash that follows the major flare on all of her

> joints that

> ached. The joints get red and then the skin peels off in layers.

> I have read so many other posts that indicate systemic patients that have

> had varrying types of skin problems. Perhaps, since Aundrea is a fair,

> blonde, blue-eyed child she is more sensitive to some of the skin

problems.

> I certainly did have a long talk with Aundrea about the meds, but she

mostly

> just cried thru the whole conversation. She was burdened about

hiding the

> pills but also hated the tummy aches and dizziness. I am still convinced

> that this is a problem from the Naproxyn because she still has these

> symptoms and of course she isn't on the pred.

>

> A question that I have and was hoping that maybe you or another

parent might

> be able to answer is regarding joint destruction. If Aundrea is just

having

> sorethoats, rash and joint pain but no swelling do I have to worry about

> joint

> destruction. Her first rheumy said that joint destruction only takes

> place when

> there is inflamation. Is this a true statement?

>

> Thanks again for your post and for this site. This place has offered

me a

> wealth of information as well as support. Thanks for taking the time to

> provide us with so many articles. I really appreciate all of your

hard work

> and efforts.

>

> Sincerely,

>