Guest guest Posted May 3, 2001 Report Share Posted May 3, 2001 I went in for all my labs yesterday, this time we are looking for scleroderma, lupus broken down into dna and double stranded dna, anti smooth muscle antibodies,anit cardiolipin antibodies, c-3 and c-4 compliments and the ANA sed rate etc again. I should know more next week and will keep you guys posted...please offer prayers for me. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 4, 2001 Report Share Posted May 4, 2001 , The dsDNA is usually a part of the ANA profile. It is much more indicative of lupus, and there are several other DNA and polypeptide agents that should be a part of your ANA profile. I, too, have antibodies to smooth and skeletal muscle. No one knows why, although my rheumy links it to the implants. I will wish you the best, and hope the tests come back okay. Please let me know how they turn out. e Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 14, 2001 Report Share Posted November 14, 2001 , Your lab results are very similar to mine. My ANA pattern was also speckled, and was at it's highest about 1 yrs prior to explantation. It gradually went down after explant, but as I've already told the group, back in Oct, it went sky high again. I haven't had my ANA or any other labs checked since, so I don't know where I'm at now. The rheumy I saw in Seattle didn't even suggest having labs done. And I was so focused on getting out of Seattle that I didn't even ask to have them done. Plus I figured I wouldn't be there for the results, anyway. So, as soon as I get my work schedule, I am going to make an appt with my rheumy here in Denver and start from square 1. e > > e, > > The ANA that i had was diffused, speckled pattern, it seemed to rise > with the implants and has fallen with removal, will it stay down now? > Who really knows right? > > I have all other labs negative, all the big ones for anticardiolipins > and double stranded dna, also my complement levels have always been > negative and so have my scloeroderma labs, and sed rate has never > ever been high so it was just the ana, which is now borderling, yet > here I am still not without aches! GO FIGURE! > > > > > > > > > > > > In @y..., eRene@a... wrote: > > Many people actually have a positive ANA, therefore it > > is not the deciding factor in forming a dx. When > > testing for lupus or other autoimmune diseases, many > > rheumys will be looking more at dble stranded DNA, > > anticardiolipin antibodies, and complement levels. > > Also, the pattern of the ANA is relevant. Many people > > have speckled, which is very common, and thus many > > people in the general population will show a speckled > > ANA pattern. Other patterns are more indicative of > > lupus, as is the result of the ANA. In other words, if > > your ANA is 1:40, 1:60, or 1:80, these are typically > > considered false positives, but can also be indicative > > of a dormant disease process. Now, if you end up with > > an ANA of 1:800 or something high like that, and/or a > > pattern that is not speckled, that is more diagnostic of > > an autoimmune disease. So you can see that diagnosing > > an autoimmune disease can be very difficult and tricky, > > hence the reason it can take yrs to dx. > > > > e > > > for those of you that don't know about ANA tests I can explain > that > > > an ANA test is considered negative in most labs(some are > different) > > > at anything below 1:40 at 1:40 and above they are considered > > > positive, but it is weak at 1:40-1:80 and above 1:80 is positive. > > > Mine was negative for the first year I had the implants and then > > > turned positive (which was also a deciding factor for me to > remove my > > > implants) it was 1:40 in August of 2000 climbing to 1:640 in Dec > > > 2000, after explant it stayed there till April, went down to > 1:140 > > > in april and now is 1:80 almost one year post explant. > > > > > > I am going to be late for an appointment or I would explain the > ANA > > > test better and what it measures for, maybe if e or Dr kolb > get > > > a chance they can explain it, but it basically measures the > amount of > > > time it takes the people running the test to get the antibodies > to > > > clear the blood, thus the number is actually the amount of times > they > > > ran the test. > > > > > > Many Dr's feel that ANA's are not that idicative in telling you > much > > > about the proscess of the disease, however I feel in my case it > is > > > telling allot since I went from nearly disabled to being quite > well > > > again and the lab work tells me that as well. > > > > > > Ok not a Dr but I know a little, now if anyone here knows a > better > > > way of explaining it that would be great! > > > > > > Love, > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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