Re: what is cavinton?

[Guest guest]

Hi Kathy,

I did not have the time to file through them, but I am sure one of those will

yield the info you were seeking,

Friendly regards,

Katharina

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[use of cavinton in epilepsy] [Article in Russian] Dutov AA, Tolpyshev

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[Guest guest]

Use of cavinton in epilepsy]

[Article in Russian]

Dutov AA, Tolpyshev BA, Petrov AP, Gladun VN.

The authors studied the effect of cavinton (15-45 mg/day) and its combinations

with different anticonvulsants on the time-course of different forms of

epilepsy. In 20 of the 31 patients studied treatment with cavinton either

significantly decreased the frequency of attacks or led to their complete

disappearance; in 7 patients the improvement was insignificant and in 4 the

condition deteriorated. The greatest effect of cavinton was observed in

generalized tonic-clonic convulsions and when they were combined with absences.

Clinical improvement not always correlated with EEG normalization. A suggestion

is made that the mechanism of the anticonvulsive action of cavinton may be

explained both by the normalization of the cerebral blood flow and elimination

of hypoxia and by the fact that the drug may possess anticonvulsive properties

unrelated to the normalization of the cerebral hemodynamics.

PMID: 3751419 [PubMed - indexed for MEDLINE]