To Clara with love..........and NAFLD

[Guest guest]

 Ha ha ha ha ha,  Harper, you beat me to it.....funny!  Hm, are there men by

that name too????   Curious...........    And Clara, we still love

ya.......... 

JJ  and that stands for Joanne  & Jeff Cathcart.  ; - )   

                                        \

                        > Thanks, Clara.

You might be interested in today's signature block, below.

>

> Good luck with the pacemaker. I hope it's working well for you.

>

> Ms. Harper

> Age 66, northern California, female

> AIH dx 2000                                   

                               

>                                           

    Now, on to NAFLD .Non Alcoholic

>Fatty Liver Disease.  First before I give the link.etc, I do want to add that

>some people can actually have a fatty liver and NOT be over weight.but have a

>fatty liver.    

>http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/hepatology/no\

nalcoholic-fatty-liver-disease/                  

>

Definition and causes

Figure 1: Click to Enlarge

Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized form of

chronic liver disease. It encompasses a spectrum of conditions associated with

lipid deposition in hepatocytes. It ranges from steatosis (simple fatty liver),

to nonalcoholic steatohepatitis (NASH—fatty changes with inflammation and

hepatocellular injury or fibrosis), to advanced fibrosis and cirrhosis (Fig. 1).

Studies have suggested that although simple fatty liver is a benign condition,

NASH may progress to fibrosis and lead to end-stage liver disease. The disease

is mostly silent and often discovered through incidentally elevated liver enzyme

levels. It is strongly associated with obesity and insulin resistance and is

currently considered by many as the hepatic component of the metabolic syndrome

(see later). NASH cirrhosis is now one of the leading indications for liver

transplantation in the United States.

Because NAFLD resembles alcoholic liver disease, but occurs in people who drink

little or no alcohol, excessive daily alcohol consumption (more than 20 g/day in

women and 30 g/day in men within the last 5 years) must be ruled out before

making the diagnosis. Numerous other conditions leading to fatty liver must be

excluded by history, physical examination, and appropriate testing (Box

1).          

Treatment

Although numerous clinical trials have been undertaken since the last American

Gastroenterological Association Technical Review on Nonalcoholic Fatty Liver

Disease, there is no consensus on the effectiveness of any therapeutic agent in

the treatment of NAFLD. Patients should avoid alcohol and other hepatotoxins.

The goal of treatment is to improve steatosis and prevent the development of

fibrosis, which may lead to cirrhosis and its complications. Because the

prognosis of NASH depends on risk factors (e.g., obesity, insulin resistance,

type 2 diabetes), these conditions have been the focus of treatment. Treatment

proposed for NAFLD has been based on the two-hit hypothesis, the first being

fatty liver infiltration (linked to obesity and insulin resistance), and the

second being oxidative stress.>                            

                   

                                            

On a personal note I will add that

in my eyes a diet put out by DaVita.(which I am currently on for my kidney

disease) will do pwonders for fatty liver. It is very low in meat as your

protien source. Example most of my protein comes from drinking a Whey protein

powder mix.and soy (chocolate).  I also only buy SILK or other organic soy

drink.one not processed by the use of chemicals.  Anyway.Go to   DaVita.com

and

read up the diet.  I have so far lost 13 pounds just eating this way........I

also eat complex carbs.etc. and snacks are simple sugars.  If diabetic you need

to use their diet for people who also have diabetes.  Good luck,  Joanne