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What Causes The Itching?

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I never had itching with AIH and never heard of it being a symptom.wild

guess, liver not removing toxins; will be interesting to read other

responses.I only began itching with the onset of the PBC overlap.

Kay

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I never had the itching until recently. It's on my abdomen & across my

shoulders. I'm curious of what the others will say.

Toni

>

> I never had itching with AIH and never heard of it being a symptom.wild

> guess, liver not removing toxins; will be interesting to read other

> responses.I only began itching with the onset of the PBC overlap.

>

> Kay

>

>

>

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I itched for two or three months before I saw a doctor; extreme jaundice

came later, then mental confusion, which I tried to hide.

Harper

In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@... writes:

> My hepatologist once mentioned that it was possible to have jaundice

> mildly enough so that the yellowing of the skin and eyes wasn't really

> noticeable but the itching would be. Is your bilirubin elevated?

>

> JoAnn

>

**************

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My hepatologist once mentioned that it was possible to have jaundice mildly

enough so that the yellowing of the skin and eyes wasn't really noticeable but

the itching would be. Is your bilirubin elevated?

JoAnn

>

> I can understand the all the other symptoms of AIH except for the itching.

Does anyone know why? Thanks!

> Robyn

>

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I have an appointment with him on May 7. I have a list to go over with him then.

Toni

>

> Have you told your doctor about this?

> Harper

>

> In a message dated 5/2/09 6:39:00 PM, twhite2@... writes:

>

>

> >

> >

> > I never had the itching until recently. It's on my abdomen & across my

> > shoulders. I'm curious of what the others will say.

> > Toni

> >

>

>

>

>

> **************

> Check all of your email inboxes from anywhere on the web.

> Try the new Email Toolbar now!

> (http://toolbar.aol.com/mail/download.html?ncid=txtlnkusdown00000027)

>

>

>

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Which RX are you using to lower ammonia levels? Lasix?

For some reason my GI (former) didn't prescribe anything for itching or

for confusion. A couple of years ago, I told my GP I felt muddled, and she

prescribed Lasix, which is a standard for ammona problems. Fortunately, before

I used it I discovered the difficulty was taking too little Prednisone for

my particular situation.

If you use Lasix or similar, some here have given advice on ways to avoid

resulting " local irritation " .

You ask if I still have problems with mental confusion. I believe that's

gone. When I first was diagnosed, I couldn't even add or subtract without

great effort. I told my GP, who made no comment. My GI never asked. I was so

frightened by my dull-wittedness that I didn't want to pursue the subject. As

my liver healed, the confusion and mental slowness vanished.

Now, no one but me can tell that I'm not " on top of my game " at times. I

took a cognitive abilities exam that lasted for many hours. I did extremely

well until I became exhausted toward the end; then I couldn't do much of

anything. This fits with what I see in myself: I'm fine until I become tired,

which happens faster than I'd expect. Then my problem-solving abilities and

short-term memory suffer.

I've never really gotten on top of energy problems. My doctors keep

promising it will happen very soon, but it hasn't. I take various medications

for

hypertension, and they sometimes affect my energy (and therefore my mental

clarity) greatly.

I'm not who I was before. I simply am not. I'm someone else, in some ways

lacking what I had before, in some ways stronger, in some ways better than

the person I used to be. It is what it is.

I can't tell you what to expect. I hear from people who do spectacular

things after treatment for AIH.

Best wishes.

Harper

AIH dx 2000

CD dx 2002

In a message dated 5/3/09 9:45:12 AM, robyn@... writes:

> My symptoms came in the same order, Harper. I talked with my GI and told

> him the foggy mind and forgetfulness was really bothering me. I asked if

> we

> could check my ammonia levels with the next blood tests (I'm doing weekly

> labs at my request) and he agreed. The results were almost double what

> they

> should be so I'm trying to bring that down with yet another Rx.yippee!! Do

> you still have problems with mental confusion, or does that go away?

>

> Robyn

>

> _____

>

> From: iverSupport-Liv [mailto: iverSupport-Liv]

> On Behalf Of flatcat9@...

> Sent: Sunday, May 03, 2009 12:10 AM

> iverSupport-Liv

> Subject: Re: [LiverSupport- Subject: Re: [LiverSupport-<wb

>

> I itched for two or three months before I saw a doctor; extreme jaundice

> came later, then mental confusion, which I tried to hide.

> Harper

>

> In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@

> <mailto:jolingerlusmailto:jolingmai> writes:

>

> > My hepatologist once mentioned that it was possible to have jaundice

> > mildly enough so that the yellowing of the skin and eyes wasn't really

> > noticeable but the itching would be. Is your bilirubin elevated?

> >

> > JoAnn

> >

>

> ************ *

> The Average US Credit Score is 692. See Yours in Just 2 Easy

> Steps!

> (http://pr.atwola.

> <

> http://pr.atwola.http://pr.atwhttp://pr.atwolahttp://pr.atwolahttp://pr.htt

> p://www.freecreditrp://www.frp://www.frep://www.freecr & <wbr>amp;hm<w & amp;>

> com/promoclk/ com/promoclk/<w com/promoclk/<w com/promo

> http://www.freecredht

> report.com/pm/ report.com/p report.c & <wbr>amp;hm<w & amp;

> bcd=May5309Avgfoote bcd=M

>

>

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Yes, Joanne, my bilirubin is a bit elevated and my AST & ALT went up a bit

this past week. Harper's response led me to the following explanation

(posted below) with a web search and I think this was the explanation I was

looking for. I found it at http://www.cancernet.co.uk/sym-itching.htm which

is site for cancer patients with tumor obstructions of bile flow, but it

addresses the liver related issue of itching. Thanks Harper.

Robyn

Liver related - If the flow of bile from the liver to the bowel is

interrupted patients become yellow (jaundiced). This is due to a build up of

bile in the blood stream which then gets deposited in the skin and whites of

the eyes. Along with bile there is a second chemical called Bile salts -

these also get deposited in the skin and cause distressing itching. Liver

problems may be associated with pain in the right upper part of the abdomen,

feeling nauseated and indigestion.

Your doctor may already know why the flow of bile in your bile duct is

impaired but if not several investigations can be performed:-

* Blood tests - for bile levels (bilirubin), liver function tests

* Liver ultrasound - looking for blockage in the bile duct

* CT or MRI or the abdomen - to see if lymph nodes are enlarged near

the end of the bile duct or cancer is seen within the liver.

* ERCP - If the tests above do not find out the problem a scope can be

passed through the mouth into the part of the bowel next to the bile duct.

Dye is injected up the duct and an xray taken - this will tell the doctors

what type of obstruction you have including non-tumor conditions such as

gall stones.

Treatment for liver related pruritis - The most effect way to relieve this

itching is to correct the normal flow of bile. If this is caused by tumor at

the base of the bile duct. Removal of this tumor may be possible either with

surgery, chemotherapy or radiotherapy. For tumors of the pancreas for

example it may be possible for the surgeon to bypass the obstruction by

moving the bile duct to another part of the bowel. It is also possible that

a plastic stent can be inserted into the bile duct at the time of ERCP (see

above) to drain the bile and bile salts.

If physical relief of the obstruction is not possible the level of bile

salts in the blood stream can be reduced by taking a medication called

Cholestyramine.

_____

From: [mailto: ]

On Behalf Of JoAnn O'Linger-Luscusk

Sent: Saturday, May 02, 2009 11:18 PM

Subject: [ ] Re: What Causes The Itching?

My hepatologist once mentioned that it was possible to have jaundice mildly

enough so that the yellowing of the skin and eyes wasn't really noticeable

but the itching would be. Is your bilirubin elevated?

JoAnn

>

> I can understand the all the other symptoms of AIH except for the itching.

Does anyone know why? Thanks!

> Robyn

>

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My symptoms came in the same order, Harper. I talked with my GI and told

him the foggy mind and forgetfulness was really bothering me. I asked if we

could check my ammonia levels with the next blood tests (I'm doing weekly

labs at my request) and he agreed. The results were almost double what they

should be so I'm trying to bring that down with yet another Rx.yippee!! Do

you still have problems with mental confusion, or does that go away?

Robyn

_____

From: [mailto: ]

On Behalf Of flatcat9@...

Sent: Sunday, May 03, 2009 12:10 AM

Subject: Re: [ ] Re: What Causes The Itching?

I itched for two or three months before I saw a doctor; extreme jaundice

came later, then mental confusion, which I tried to hide.

Harper

In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@

<mailto:jolingerluscusk%40> writes:

> My hepatologist once mentioned that it was possible to have jaundice

> mildly enough so that the yellowing of the skin and eyes wasn't really

> noticeable but the itching would be. Is your bilirubin elevated?

>

> JoAnn

>

**************

The Average US Credit Score is 692. See Yours in Just 2 Easy

Steps!

(http://pr.atwola.

<http://pr.atwola.com/promoclk/100126575x1222376998x1201454298/aol?redir=htt

p://www.freecreditreport.com/pm/default.aspx?sc=668072 & amp;hmpgID=62 & amp;>

com/promoclk/100126575x1222376998x1201454298/aol?redir=http://www.freecredit

report.com/pm/default.aspx?sc=668072 & amp;hmpgID=62 & amp;

bcd=May5309AvgfooterNO62)

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I was given lactulose for my ammonia levels, lasix is a fluid pill to take fluid

off your body. Lactulose helped me alot.

Lori C.

AH/ Liver TX 3-11-1997

Re: [LiverSupport-<wb

>

> I itched for two or three months before I saw a doctor; extreme jaundice

> came later, then mental confusion, which I tried to hide.

> Harper

>

> In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@

> <mailto:jolingerlusmailto:jolingmai> writes:

>

> > My hepatologist once mentioned that it was possible to have jaundice

> > mildly enough so that the yellowing of the skin and eyes wasn't really

> > noticeable but the itching would be. Is your bilirubin elevated?

> >

> > JoAnn

> >

>

> ************ *

> The Average US Credit Score is 692. See Yours in Just 2 Easy

> Steps!

> (http://pr.atwola.

> <

> http://pr.atwola.http://pr.atwhttp://pr.atwolahttp://pr.atwolahttp://pr.htt

> p://www.freecreditrp://www.frp://www.frep://www.freecr & <wbr>amp;hm<w & amp;>

> com/promoclk/ com/promoclk/<w com/promoclk/<w com/promo

> http://www.freecredht

> report.com/pm/ report.com/p report.c & <wbr>amp;hm<w & amp;

> bcd=May5309Avgfoote bcd=M

>

>

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I've started taking Lactulose Solution to loosen stools and move the ammonia

out that way. He said that's the only way to remove the excess ammonia.

I find that stress seems to trigger confusion. I used to be able to handle

just about anything, now I get frustrated and have difficulty dealing with

issues at work. Fortunately, I work for my husband and he is very aware of

my situation and if I am having a bad day, I can just go home and rest.

Here's another question for you. I'm getting ready to fly home to IL for 10

days. My entire family lives in IL and I used to fly home every other month

or so. I haven't been home since Christmas and my kids and grandchildren

are getting a bit grumpy and with my recent dx just want to see me to make

sure I'm ok. Any thing I need to be aware of while traveling? I've never

had to take Rx before, is there something I need to have with me to take

this through security? Any other advice?

Thanks, Robyn

_____

From: [mailto: ]

On Behalf Of flatcat9@...

Sent: Sunday, May 03, 2009 10:35 AM

Subject: Re: [ ] Re: What Causes The Itching?

Which RX are you using to lower ammonia levels? Lasix?

For some reason my GI (former) didn't prescribe anything for itching or

for confusion. A couple of years ago, I told my GP I felt muddled, and she

prescribed Lasix, which is a standard for ammona problems. Fortunately,

before

I used it I discovered the difficulty was taking too little Prednisone for

my particular situation.

If you use Lasix or similar, some here have given advice on ways to avoid

resulting " local irritation " .

You ask if I still have problems with mental confusion. I believe that's

gone. When I first was diagnosed, I couldn't even add or subtract without

great effort. I told my GP, who made no comment. My GI never asked. I was so

frightened by my dull-wittedness that I didn't want to pursue the subject.

As

my liver healed, the confusion and mental slowness vanished.

Now, no one but me can tell that I'm not " on top of my game " at times. I

took a cognitive abilities exam that lasted for many hours. I did extremely

well until I became exhausted toward the end; then I couldn't do much of

anything. This fits with what I see in myself: I'm fine until I become

tired,

which happens faster than I'd expect. Then my problem-solving abilities and

short-term memory suffer.

I've never really gotten on top of energy problems. My doctors keep

promising it will happen very soon, but it hasn't. I take various

medications for

hypertension, and they sometimes affect my energy (and therefore my mental

clarity) greatly.

I'm not who I was before. I simply am not. I'm someone else, in some ways

lacking what I had before, in some ways stronger, in some ways better than

the person I used to be. It is what it is.

I can't tell you what to expect. I hear from people who do spectacular

things after treatment for AIH.

Best wishes.

Harper

AIH dx 2000

CD dx 2002

In a message dated 5/3/09 9:45:12 AM, robynbottens (DOT)

<mailto:robyn%40bottens.com> com writes:

> My symptoms came in the same order, Harper. I talked with my GI and told

> him the foggy mind and forgetfulness was really bothering me. I asked if

> we

> could check my ammonia levels with the next blood tests (I'm doing weekly

> labs at my request) and he agreed. The results were almost double what

> they

> should be so I'm trying to bring that down with yet another Rx.yippee!! Do

> you still have problems with mental confusion, or does that go away?

>

> Robyn

>

> _____

>

> From: iverSupport-Liv [mailto: iverSupport-Liv]

> On Behalf Of flatcat9aol (DOT) <mailto:flatcat9%40aol.fla> fla

> Sent: Sunday, May 03, 2009 12:10 AM

> iverSupport-Liv

> Subject: Re: [LiverSupport- Subject: Re: [LiverSupport-<wb

>

> I itched for two or three months before I saw a doctor; extreme jaundice

> came later, then mental confusion, which I tried to hide.

> Harper

>

> In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@

> <mailto:jolingerlusmailto:jolingmai> writes:

>

> > My hepatologist once mentioned that it was possible to have jaundice

> > mildly enough so that the yellowing of the skin and eyes wasn't really

> > noticeable but the itching would be. Is your bilirubin elevated?

> >

> > JoAnn

> >

>

> ************ *

> The Average US Credit Score is 692. See Yours in Just 2 Easy

> Steps!

> (http://pr.atwola.

> <

> http://pr.atwola.

<http://pr.atwola.http:/pr.atwhttp:/pr.atwolahttp:/pr.atwolahttp:/pr.htt>

http://pr.atwhttp://pr.atwolahttp://pr.atwolahttp://pr.htt

> p://www.freecreditr <p://www.freecreditrp:/www.frp:/www.frep:/www.freecr & >

p://www.frp://www.frep://www.freecr & <wbr>amp;hm<w & amp;>

> com/promoclk/ com/promoclk/<w com/promoclk/<w com/promo

> http://www.freecred <http://www.freecredht> ht

> report.com/pm/ report.com/p report.c & <wbr>amp;hm<w & amp;

> bcd=May5309Avgfoote bcd=M

>

>

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That's what he gave me, Lactulose. Just started it last night, had my

second dose this morning, but haven't seen any results yet!!

Robyn

_____

From: [mailto: ]

On Behalf Of Lori Cummins

Sent: Sunday, May 03, 2009 10:48 AM

Subject: Re: [ ] Re: What Causes The Itching?

I was given lactulose for my ammonia levels, lasix is a fluid pill to take

fluid off your body. Lactulose helped me alot.

Lori C.

AH/ Liver TX 3-11-1997

Re: [LiverSupport-<wb

>

> I itched for two or three months before I saw a doctor; extreme jaundice

> came later, then mental confusion, which I tried to hide.

> Harper

>

> In a message dated 5/2/09 11:19:06 PM, jolingerluscusk@

> <mailto:jolingerlusmailto:jolingmai> writes:

>

> > My hepatologist once mentioned that it was possible to have jaundice

> > mildly enough so that the yellowing of the skin and eyes wasn't really

> > noticeable but the itching would be. Is your bilirubin elevated?

> >

> > JoAnn

> >

>

> ************ *

> The Average US Credit Score is 692. See Yours in Just 2 Easy

> Steps!

> (http://pr.atwola.

> <

> http://pr.atwola.

<http://pr.atwola.http:/pr.atwhttp:/pr.atwolahttp:/pr.atwolahttp:/pr.htt>

http://pr.atwhttp://pr.atwolahttp://pr.atwolahttp://pr.htt

> p://www.freecreditr <p://www.freecreditrp:/www.frp:/www.frep:/www.freecr & >

p://www.frp://www.frep://www.freecr & <wbr>amp;hm<w & amp;>

> com/promoclk/ com/promoclk/<w com/promoclk/<w com/promo

> http://www.freecred <http://www.freecredht> ht

> report.com/pm/ report.com/p report.c & <wbr>amp;hm<w & amp;

> bcd=May5309Avgfoote bcd=M

>

>

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Well I went to my appt. on Thursday & my numbers are up. He upped my predinsone

from 5mg to 20mg. & gave me a ranitidine tablet to take at night along with my

nexium in the morning for my stomach. I have to go in 2 wks for more blood work

along with a test for my azathioprine levels. I have never had that one done

before.

I did feel a little rushed at this appt. The office was packed when I got there.

My appt. was for 3 & I didn't get to see him until 4. I have never had that

happen before. I usually in & out within a 1/2 hr.

Toni

> >

> > Have you told your doctor about this?

> > Harper

> >

> > In a message dated 5/2/09 6:39:00 PM, twhite2@ writes:

> >

> >

> > >

> > >

> > > I never had the itching until recently. It's on my abdomen & across my

> > > shoulders. I'm curious of what the others will say.

> > > Toni

> > >

> >

> >

> >

> >

> > **************

> > Check all of your email inboxes from anywhere on the web.

> > Try the new Email Toolbar now!

> > (http://toolbar.aol.com/mail/download.html?ncid=txtlnkusdown00000027)

> >

> >

> >

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