Guest guest Posted May 7, 2001 Report Share Posted May 7, 2001 From: " ilena rose " <ilena@...> Sent: Sunday, May 06, 2001 12:08 PM Subject: Silicone-Injected Mice Produce More Immune Proteins > ~~~ thanks chris and myrl ~~~ > > Silicone-Injected Mice Produce More Immune Proteins > > Mice exposed to silicone oils or gels develop immune-system > abnormalities, according to researchers from Rochester General Hospital > and the University of Florida. > > They report their findings in the May issue of the journal Clinical and > Diagnostic Laboratory Immunology. > > " Although most published epidemiological studies have found little > evidence of systemic autoimmune disease associated with silicone breast > implants, there still remains a question of whether silicones can cause > local and/or systemic immune dysfunction, " the researchers say. > > To answer this question, the researchers injected mice with silicone gel > and silicone oil to see what would happen. > > Compared to control mice, the silicone-injected mice produced > significantly more of certain immune system proteins in a pattern > similar to experimentally produced lupus in mice. > > It is important to note, however, that silicone did not induce the > development of autoantibodies. > > " These observations may be relevant to understanding the vague and often > poorly defined autoimmune-like phenomena occurring in certain > individuals with silicone implants, " say the researchers. " However, > further experimental and clinical studies will be necessary to address > this question. " > > (J.O. Naim, M. Satoh, N.A. Buehner, K.M.L. Ippolito, H. Yoshida, D. > Nusz, L. Kurtelawicz, S.F. Cramer, and W.H. Reeves. 2000. Induction of > hypergammaglobulinemia and macrophage activation by silicone gels and > oils in female A.SW mice. Clinical and Diagnostic Laboratory Immunology, > 7: 366-370.) > > > 23-May-2000 > > Quote Link to comment Share on other sites More sharing options...
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