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Re: Tylenol/Ibuprofen

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Tylenol is perfectly safe to take. It has been studied

in people with liver disease and has been found to be

one of the safest things to take. The most recent of

these studied doses of 3 grams daily, which is the

same as 2 extra strength every 8 hours. It is not an

irritant, or toxic in normal doses, except in rare

cases of alcohol use or starvation. It is only toxic

to the liver if it is taken in LARGE doses (ie 10

grams), or with alcohol or possibly in cases of

starvation. On the other hand, ibuprofen has been

shown to cause elevations in liver function tests

which can persist for months in those with liver

disease. In fact, if you go to http://www.rxlist.com

and look up ibuprofen, and look under warnings, this

is what is shown:

Liver Effects: As with other nonsteroidal

anti-inflammatory drugs, borderline elevations of one

or more liver function tests may occur in up to 15% of

patients. These abnormalities may progress, may remain

essentially unchanged, or may be transient with

continued therapy. The SGPT (ALT) test is probably the

most sensitive indicator of liver dysfunction.

Meaningful (3 times the upper limit of normal)

elevations of SGPT or SGOT (AST) occurred in

controlled clinical trials in less than 1% of

patients. A patient with symptoms and/or signs

suggesting liver dysfunction, or in whom an abnormal

liver test has occurred, should be evaluated for

evidence of the development of more severe hepatic

reactions while on therapy with ibuprofen. Severe

hepatic reactions, including jaundice and cases of

fatal hepatitis, have been reported with ibuprofen as

with other nonsteroidal anti-inflammatory drugs.

Although such reactions are rare, if abnormal liver

tests persist or worsen, if clinical signs and

symptoms consistent with liver disease develop, or if

systemic manifestations occur (e.g., eosinophilia,

rash, etc), ibuprofen should be discontinued.

--- 2byteme@... wrote:

> If you can stay away from the products with tylenol.

> While small amounts

> will probably not cause any problems, since tylenol

> is a known liver

> irritant, if possible, why take a chance. If that

> works for someone,

> small doses will probably not hurt, but, it needs to

> remain in small

> doses, which is usually 2 of the normal strength

> every 6-8 hours,

> maximum. If you can substitute ibuprofen, that is

> better, but many can

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Tylenol is perfectly safe to take. It has been studied

in people with liver disease and has been found to be

one of the safest things to take. The most recent of

these studied doses of 3 grams daily, which is the

same as 2 extra strength every 8 hours. It is not an

irritant, or toxic in normal doses, except in rare

cases of alcohol use or starvation. It is only toxic

to the liver if it is taken in LARGE doses (ie 10

grams), or with alcohol or possibly in cases of

starvation. On the other hand, ibuprofen has been

shown to cause elevations in liver function tests

which can persist for months in those with liver

disease. In fact, if you go to http://www.rxlist.com

and look up ibuprofen, and look under warnings, this

is what is shown:

Liver Effects: As with other nonsteroidal

anti-inflammatory drugs, borderline elevations of one

or more liver function tests may occur in up to 15% of

patients. These abnormalities may progress, may remain

essentially unchanged, or may be transient with

continued therapy. The SGPT (ALT) test is probably the

most sensitive indicator of liver dysfunction.

Meaningful (3 times the upper limit of normal)

elevations of SGPT or SGOT (AST) occurred in

controlled clinical trials in less than 1% of

patients. A patient with symptoms and/or signs

suggesting liver dysfunction, or in whom an abnormal

liver test has occurred, should be evaluated for

evidence of the development of more severe hepatic

reactions while on therapy with ibuprofen. Severe

hepatic reactions, including jaundice and cases of

fatal hepatitis, have been reported with ibuprofen as

with other nonsteroidal anti-inflammatory drugs.

Although such reactions are rare, if abnormal liver

tests persist or worsen, if clinical signs and

symptoms consistent with liver disease develop, or if

systemic manifestations occur (e.g., eosinophilia,

rash, etc), ibuprofen should be discontinued.

--- 2byteme@... wrote:

> If you can stay away from the products with tylenol.

> While small amounts

> will probably not cause any problems, since tylenol

> is a known liver

> irritant, if possible, why take a chance. If that

> works for someone,

> small doses will probably not hurt, but, it needs to

> remain in small

> doses, which is usually 2 of the normal strength

> every 6-8 hours,

> maximum. If you can substitute ibuprofen, that is

> better, but many can

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  • 5 years later...
Guest guest

I had been wondering if that could be a factor,too. I was told to take tylenol

(instead of ibuprofen) after both of my biopsies-due to risk of blleding at the

site. When my momm had varicies, she was told that she couldn't take either one.

[ ] Tylenol/Ibuprofen

Not to beat this into the ground...

but have the folks who have been told to choose tylenol products over

ibuprofen (or other NSAIDS)had bleeding problems?

I was instructed to take ibuprofen for pain (cramps, headaches, etc)

until I started having problems with varices. Then, because of the

danger of bleeding and what NSAIDS do to thin your blood, I was told

to take Tylenol. Of course, I would say that I don't even take 500 mg

every couple of months (except for when I had the flu and needed to

keep my fever down), so that's a factor too.

Shirl (WA)

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Guest guest

Yes I think it all depends on everyone's situation. Each doctor is

different and I also think it depends on the severity of one's AIH

>

> Not to beat this into the ground...

>

> but have the folks who have been told to choose tylenol products

over

> ibuprofen (or other NSAIDS)had bleeding problems?

>

> I was instructed to take ibuprofen for pain (cramps, headaches,

etc)

> until I started having problems with varices. Then, because of

the

> danger of bleeding and what NSAIDS do to thin your blood, I was

told

> to take Tylenol. Of course, I would say that I don't even take 500

mg

> every couple of months (except for when I had the flu and needed

to

> keep my fever down), so that's a factor too.

>

> Shirl (WA)

>

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Guest guest

This is exactly my dilemma! I have arthritis and varices and acid stomach and

possible reflux problems, and..........

So I take Ibuprofen when necessary and take aciphex to control the acid problem

from which the bleeding of the varices becomes dangerous. I have been bad, I

have been taking 200 mg of Ibuprofen for the last few weeks at night, so I

could sleep. I seemed to have developed a hip ache problems. Arthritis ?????

Yes, I am trying to control that with glucosamine. It is working most of the

time, but if I do not take it even for one day I can feel it. I will have to

super double up on it and see if it helps, so I can get off of Ibuprofen .

Clara from OR

PS. Is there anyone in the Portland Beaverton area who is chatting on this

list?? We ought to find each other.

[ ] Tylenol/Ibuprofen

Not to beat this into the ground...

but have the folks who have been told to choose tylenol products over

ibuprofen (or other NSAIDS)had bleeding problems?

I was instructed to take ibuprofen for pain (cramps, headaches, etc)

until I started having problems with varices. Then, because of the

danger of bleeding and what NSAIDS do to thin your blood, I was told

to take Tylenol. Of course, I would say that I don't even take 500 mg

every couple of months (except for when I had the flu and needed to

keep my fever down), so that's a factor too.

Shirl (WA)

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Guest guest

I wonder if you could take something else to help you sleep, if you're worried

about taking the Ibuprofen for your hip pain. I take Ambien at night and sleep

much better than I used to. My mom used to lay awake all night when she was ill

(before her transplant) and only took a couple of short naps during the day. I

sleep pretty well with this medication but still wake about about 4:30 a.m.

Clara Shelton <cshelton33@...> wrote: This is exactly my dilemma! I

have arthritis and varices and acid stomach and possible reflux problems,

and..........

So I take Ibuprofen when necessary and take aciphex to control the acid problem

from which the bleeding of the varices becomes dangerous. I have been bad, I

have been taking 200 mg of Ibuprofen for the last few weeks at night, so I

could sleep. I seemed to have developed a hip ache problems. Arthritis ?????

Yes, I am trying to control that with glucosamine. It is working most of the

time, but if I do not take it even for one day I can feel it. I will have to

super double up on it and see if it helps, so I can get off of Ibuprofen .

Clara from OR

PS. Is there anyone in the Portland Beaverton area who is chatting on this

list?? We ought to find each other.

[ ] Tylenol/Ibuprofen

Not to beat this into the ground...

but have the folks who have been told to choose tylenol products over

ibuprofen (or other NSAIDS)had bleeding problems?

I was instructed to take ibuprofen for pain (cramps, headaches, etc)

until I started having problems with varices. Then, because of the

danger of bleeding and what NSAIDS do to thin your blood, I was told

to take Tylenol. Of course, I would say that I don't even take 500 mg

every couple of months (except for when I had the flu and needed to

keep my fever down), so that's a factor too.

Shirl (WA)

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