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He also sells it. Site:

"OSR#1® assists glutathione in its job of scavenging free radicals and may help the body maintain a healthy glutathione level.

Glutathione is the body's natural defense to free radicals. However, once glutathione stabilizes a free radical, it becomes oxidized and is usually excreted from the body. This lowers the body's level of glutathione, and high levels of oxidative stress can prevent the body from recovering its normal functioning. "

https://www.ctiscience.com/CTIScience/Home.do

True, but for sparing glutathione so does vit C, E, and ALA along with other antioxidants. So OSR is a new kid on the block, made by them, and they don't say what it's composed of. I wouldn't consider it.

Several things "raise" glutathione in a supportive way,

true non denatured whey protein supplies all the building blocks and is the best way by far. Keyword=non denatured.

The reduced glutathione molecule consists of three amino acids - glutamic acid, cysteine, and glycine. The body manufactures it from these building blocks inside the cell. Cysteine is the limiting factor best supplied by whey...unless one likes raw meat, or unpasturized milk has a little.

Helps:

NAC - traditional, a pharmaceutical drug with some side effects, supplies limiting factor cysteine.

Supportive:

Alpha-Lipoic Acid

milk thistle

C & E

Others

Bruce

more info

I currently take 62.5 mg Iodoral and companion supplements. I am wondering how important selenium is to the protocol. It was suggested that I may have an RT3 issue but I have not had a chance to be tested. So when I read the following I became concerned that maybe I should rethink selenium. Would the lack of it affect the body's ability to utilize iodine?"Selenium is known to improve conversion of T4 to T3, so it's also going to accelerate conversion of T4 to RT3 if you are making too much as it is."If a person has an RT3 issue, how should we handle selenium supplementation? Thanks,

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Some on rt3 by

Kent Holtorf

Medical Director, Holtorf Medical Group

" This leptin resistance is sensed as starvation, so multiple mechanisms are

activated to increase fat stores, rather than burn excess fat stores. Leptin

resistance also stimulates the formation of reverse T3, which blocks the

effects of thyroid hormone on metabolism (discussed below)....

The studies are showing that it is not the production of thyroid that is the

problem, but rather it is problem inside the cell that the inactive T4 is

not converted to T3 but rather to a mirror image of T3 called reverse T3.

The reverse T3 has the opposite effect of T3, blocking the effects of T3 and

lowering rather than increasing metabolism.

It is an evolutionary fall-back that was useful in times of famine or in

hibernating animals to lower metabolism. Studies are showing that stress and

dieting (especially yo-yo dieting) can set this hormone into action as well

as chronic illness such as diabetes, chronic fatigue syndrome and

fibromyalgia. ...

....because the problem is not the amount of T4 but rather the excess

conversion of T4 to reverse T3, blocking effects of the active T3. One must

bypass the abnormality by supplementing with physiologic doses of T3, not T4

(preferably timed released T3). It is not appropriate to give thyroid

hormone for weight loss, but rather to correct an abnormality diagnosed by

appropriate blood tests.. "

http://www.huffingtonpost.com/kent-holtorf/long-term-weight-loss---m_b_192933.ht\

ml

Bruce

----- Original Message -----

From: ladybugsandbees

I am researching this right now but from what I am gathering there are a

couple of key components to overcoming the RT3 - I have an interest in this

because I have a rT3 of 405.

1. Iodine to create hormones - normalized function.

2. Selenium - Created / activate the Deiodinase (D1, D2, D3)

3. Zinc - Needed in the proteins of the cells to utilize thyroid hormone

and ??? still working on this.

4. Glutithione - for which selenium is needed - helps to detoxify the liver

which is key in rT3 issues as the liver is usually overloaded hence

conversion issues.

5. Adrenals - cortisol creates an issue with increasing rT3 levels. I have

seen loose references to the adrenals needs for Se.

It isn't in isolation. I know that on other groups they are saying " flat

out " no Se with rT3 but I am not convinced. Dr. Brownstein uses liver

detoxification and diet to clear up rT3 with sucess. I am doing the liver

detoxing right now.

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Hi ,

I had more muscle stiffness and achy joints when I was taking the higher doses

of Selenium as part of the Iodine Protocol but did not know why. Now I think it

may have been RT3, but unable to do testing. So now I have really backed off

the Se, and only do 200 mcg daily most days of the week. I have since

implemented other liver/kidney support detox mechanisms in addition to the salt

loading, i.e., herbs.

Bev P.

>

> I currently take 62.5 mg Iodoral and companion supplements. I am wondering how

important selenium is to the protocol. It was suggested that I may have an RT3

issue but I have not had a chance to be tested. So when I read the following I

became concerned that maybe I should rethink selenium. Would the lack of it

affect the body's ability to utilize iodine?

>

>

> " Selenium is known to improve conversion of T4 to T3, so it's also going to

accelerate conversion of T4 to RT3 if you are making too much as it is. "

>

> If a person has an RT3 issue, how should we handle selenium supplementation?

>

> Thanks,

>

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Bev P.

It's never simple is it? We learn so much from each other. I am so thankfull for resources that we have available to us. Thanks for sharing.

From: norxgirl <bevpirt@...>iodine Sent: Fri, February 19, 2010 1:59:57 PMSubject: Re: more info

Hi ,I had more muscle stiffness and achy joints when I was taking the higher doses of Selenium as part of the Iodine Protocol but did not know why. Now I think it may have been RT3, but unable to do testing. So now I have really backed off the Se, and only do 200 mcg daily most days of the week. I have since implemented other liver/kidney support detox mechanisms in addition to the salt loading, i.e., herbs.Bev P.>> I currently take 62.5 mg Iodoral and companion supplements. I am wondering how important selenium is to the protocol. It was suggested that I may have an RT3 issue but I have not had a chance to be tested. So when I read the following I became concerned that maybe I should rethink selenium. Would the lack of it

affect the body's ability to utilize iodine?> > > "Selenium is known to improve conversion of T4 to T3, so it's also going to accelerate conversion of T4 to RT3 if you are making too much as it is."> > If a person has an RT3 issue, how should we handle selenium supplementation? > > Thanks, >

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stephanie, sorry to hear that you are not feeling well. nothing worse than chronic issues . it is draining. diane, near philly, pa On Feb 19, 2010, at 12:21 AM, BELINDA CARR wrote:am praying for you steph. Nut to sound selfish but we all need your wisdom and knowledge, the more you learn the more you sharethanks,belinda iodine From: ladybugsandbeessbcglobal (DOT) netDate: Thu, 18 Feb 2010 22:53:15 -0500Subject: Re: more info It's time consuming because you have to read the research articles. Since I do research I have access to a lot of the databases and it takes time to track down abstracts. But I am motivated since it is my health and I am at a VERY low point in my health right now. Having a hard time functioning both physically and mentally. I need answers. Steph more info I currently take 62.5 mg Iodoral and companion supplements. I am wondering how important selenium is to the protocol. It was suggested that I may have an RT3 issue but I have not had a chance to be tested. So when I read the following I became concerned that maybe I should rethink selenium. Would the lack of it affect the body's ability to utilize iodine?"Selenium is known to improve conversion of T4 to T3, so it's also going to accelerate conversion of T4 to RT3 if you are making too much as it is."If a person has an RT3 issue, how should we handle selenium supplementation? Thanks, Hotmail: Trusted email with Microsoft’s powerful SPAM protection. Sign up now.

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I am doing better - it's those darn adrenals. I so wish I would have never done 3 RAI's. They just trashed my body.

Steph

more info

I currently take 62.5 mg Iodoral and companion supplements. I am wondering how important selenium is to the protocol. It was suggested that I may have an RT3 issue but I have not had a chance to be tested. So when I read the following I became concerned that maybe I should rethink selenium. Would the lack of it affect the body's ability to utilize iodine?"Selenium is known to improve conversion of T4 to T3, so it's also going to accelerate conversion of T4 to RT3 if you are making too much as it is."If a person has an RT3 issue, how should we handle selenium supplementation? Thanks,

Hotmail: Trusted email with Microsoft’s powerful SPAM protection. Sign up now.

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  • 8 months later...

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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I would strongly recommend NOT getting any type of nuclear or other radiation

testing. Instead ask for an MRI which is excellent at showing soft tissue in the

body. I would not

want to irradiate any nodules which might excite them to start growing. There

are many

people who have thyroid nodules and don't even know it, an nothing happens.

 

I'm not saying don't get tested, I'm just saying get the safest kind of testing

and not the

one that could cause worse or more problems.

 

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

From: H <macbarb0503@...>

Subject: More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid.  The largest being .8 x .6, although they didn't tell me what kind

of measurement that is.  The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid.  Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17.  They weren't going to get me in until January. 

After my doctor called at my request, they made the November appointment.  I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine.  I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small. 

There sure is a lot to learn.

Thanks,

Barb

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Thanks Roni. When the nurse called today, I told her I don't want this test.

She's going to ask the doctor about the MRI.

Barb

More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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I do think it pays to be prudent about all radiation done to our bodies,

especially when

there might be cancer concerns.

 

http://thyroid.about.com/od/gettestedanddiagnosed/a/imagingtests.htm

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

From: H <macbarb0503@...>

Subject: More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid.  The largest being .8 x .6, although they didn't tell me what kind

of measurement that is.  The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid.  Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17.  They weren't going to get me in until January. 

After my doctor called at my request, they made the November appointment.  I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine.  I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small. 

There sure is a lot to learn.

Thanks,

Barb

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Here's another site I found.

 

http://www.cumc.columbia.edu/dept/thyroid/nodules.html

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

From: H <macbarb0503@...>

Subject: More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid.  The largest being .8 x .6, although they didn't tell me what kind

of measurement that is.  The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid.  Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17.  They weren't going to get me in until January. 

After my doctor called at my request, they made the November appointment.  I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine.  I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small. 

There sure is a lot to learn.

Thanks,

Barb

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Thank you Roni. That information sure backs up what you wrote earlier about why

you would definitely not have the test. I'm glad you told me, because who needs

a test that might do more harm?

Barb

More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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That's very good information. Thanks again Roni. When I asked the nurse how

the bi-lateral small nodules explain the enlarged thyroid on the left side, or

whatever it is that show on the thyroid. She was speechless. Then she asked me

if I meant the right side, and I said that it was on the left. My doctor

hadn't seen it, because the medical group just started a Saturday walk in

clinic. I noticed it on a Friday night, so went there on Saturday.

More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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It drives me crazy when one of the doctors I see doesn't pick up on something.

It makes me feel that they should pay me for figuring out what is going on

instead of them getting paid to do not much of anything worthwhile.

 

Please make sure that once this doctor has finalized his diagnosis to go get

another opinion from another doctor that deals with thyroid problems and knows

what it's all about. It would be great if you could go to one of the best

hospitals for a diagnosis, or even treatment. I have a list of the top hospitals

if you want it.

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

From: H <macbarb0503@...>

Subject: More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid.  The largest being .8 x .6, although they didn't tell me what kind

of measurement that is.  The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid.  Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17.  They weren't going to get me in until January. 

After my doctor called at my request, they made the November appointment.  I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine.  I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small. 

There sure is a lot to learn.

Thanks,

Barb

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Roni,

I understand exactly how you feel, because that's how I'm feeling. They're

supposed to know what's going on. I don't think I'll be getting the diagnosis

from this doctor, because he's referring me to an endocronologist. I do plan to

get another opinion though, and would love to have the list of top hospitals.

I checked that on-line, but none of the top ten I found were in FL. Since I

don't remember if I checked " top ten " or " top ten for thyroid, " your list might

be differnt. While reading the lists in the past, I noticed that a hospital

that was great in one specialty, may not have been the best place to go for

another. The Mayo Clinic in Rochester, Minnesota was listed with a mention that

they also have clinics in ville, FL and somewhere else. ville is

only a few hours from here, but I don't know if it's considered one of the top

ten, since it's not the one in Rochester.

Barb

More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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The list I have is from U.S.News and World Report

 

1. s Hopkins, Baltimore 30 points in 15 specialties

2. Mayo clinic, Rochester, Minn. 28 points in 15 speciaties

3. Massachusetts General, Boston, 27 points 15 specialties

4.Cleveland Clinic, 26 points in 13 specialties

5. Reagan UCLA Medical Center, LA 24 points in 14 specialties

 

The others are all too far. I would call the Mayo Clinic and ask them your

questions about their facility in Fla. It says that s Hopkins has topped the

list for the last 20 years. That's pretty

impressive.

 

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

From: H <macbarb0503@...>

Subject: More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid.  The largest being .8 x .6, although they didn't tell me what kind

of measurement that is.  The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid.  Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17.  They weren't going to get me in until January. 

After my doctor called at my request, they made the November appointment.  I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine.  I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small. 

There sure is a lot to learn.

Thanks,

Barb

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Barb,

You wrote:

>

>

> Today I learned that the ultrasound shows several small bi-lateral

> nodules on the thyroid. The largest being .8 x .6, although they didn't

> tell me what kind of measurement that is.

Usually in centimeters.

> ...I did some reading about the nuclear Thyroid scan and it

> seems to involve more x-rays and radioactive iodine. I wonder if this

> test is necessary, since from what I've read a needle biopsy is usually

> used on suspect nodules, uless they are too small.

It is essential and not very invasive. Very low doses of iodine and

radiation are involved.

The biopsy will categorize the type of cells in the nodules. The scan is

necessary to show whether any cells have spread beyond the nodules. It

will also show the biochemical activity of the nodules, whether they

take up iodine and are actively producing hormones or not.

I believe with more than three nodules greater than 0.5 cm, you may need

thyroidectomy followed by radioactive iodine ablation to " mop up. " If

the biopsy shows the nodules are completely benign and contained, they

may opt for just treating the hormone issues. They will really need both

types of tests to reliably make that decision.

Chuck

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On 10/26/2010 2:16 PM, Roni Molin wrote:

> I would strongly recommend NOT getting any type of nuclear or other

> radiation testing. Instead ask for an MRI which is excellent at showing

> soft tissue in the body. I would not

> want to irradiate any nodules which might excite them to start growing....

The iodine scan will not use anywhere near enough iodine to risk that.

It is below the RDA. It will also show some critical potentialities that

the MRI cannot do.

We recently went through this with my son and all the arguments pro and

con. The endos won. :)

Chuck

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<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

>

>

> Today I learned that the ultrasound shows several small bi-lateral

> nodules on the thyroid. The largest being .8 x .6, although they didn't

> tell me what kind of measurement that is.

Usually in centimeters.

> ...I did some reading about the nuclear Thyroid scan and it

> seems to involve more x-rays and radioactive iodine. I wonder if this

> test is necessary, since from what I've read a needle biopsy is usually

> used on suspect nodules, uless they are too small.

It is essential and not very invasive. Very low doses of iodine and

radiation are involved.

The biopsy will categorize the type of cells in the nodules. The scan is

necessary to show whether any cells have spread beyond the nodules. It

will also show the biochemical activity of the nodules, whether they

take up iodine and are actively producing hormones or not.

I believe with more than three nodules greater than 0.5 cm, you may need

thyroidectomy followed by radioactive iodine ablation to " mop up. " If

the biopsy shows the nodules are completely benign and contained, they

may opt for just treating the hormone issues. They will really need both

types of tests to reliably make that decision.

Chuck

------------------------------------

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I know what you're saying, it's still possible since we all react differently.

Some people's thyroids

react to the iodine in a CT scan and some don't.

 

One question I do have about the needle biopsy, could this procedure precipitate

any leaks of

cells into the surrounding area while withdrawing the needle or even with the

initial penetration?

<>Roni

Immortality exists!

It's called knowledge!

 

Just because something isn't seen

doesn't mean it's not there<>

> I would strongly recommend NOT getting any type of nuclear or other

> radiation testing. Instead ask for an MRI which is excellent at showing

> soft tissue in the body. I would not

> want to irradiate any nodules which might excite them to start growing....

The iodine scan will not use anywhere near enough iodine to risk that.

It is below the RDA. It will also show some critical potentialities that

the MRI cannot do.

We recently went through this with my son and all the arguments pro and

con. The endos won. :)

Chuck

------------------------------------

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Thanks Roni. I appreciate that information, and will save it. I hope I won't

need it, but even if I don't someone else might, and I'll pass it along.

Barb

More Info

hypothyroidism

Date: Tuesday, October 26, 2010, 8:49 AM

Today I learned that the ultrasound shows several small bi-lateral nodules on

the thyroid. The largest being .8 x .6, although they didn't tell me what kind

of measurement that is. The report of several small nodules doesn't explain the

noticable lump on my neck over the thyroid. Does anyone have any thoughts on

this?

Also, I'm being sent for some type of nuclear test, and won't see the

endocronologist until 11-17. They weren't going to get me in until January.

After my doctor called at my request, they made the November appointment. I did

some reading about the nuclear Thyroid scan and it seems to involve more x-rays

and radioactive iodine. I wonder if this test is necessary, since from what

I've read a needle biopsy is usually used on suspect nodules, uless they are too

small.

There sure is a lot to learn.

Thanks,

Barb

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Thanks for your opinion Chuck. So, if I'm understanding you right, the MRI will

not reveal everything that needs to be known? Is there a possibility that if

the nodules are benign, this test could activate them and make them malignant?

It does seem to make sense. Also, even though it's a small dose, I'm a very

small person and mistakes in dosage aren't that uncommon are they?

Oh how I hate the thought of surgery! Don't we all? I was hoping that could be

avoided. All I know is the size of the largest nodule. It's .8 x .6 cm. I

wasn't told the size of the others, but am going to pick up a copy of the test

results today.

Thanks for you input. I'll let you know if I can decipher anything else from

the test results. No doubt, there will be more questions.

Barb

Re: More Info

Barb,

You wrote:

>

>

> Today I learned that the ultrasound shows several small bi-lateral

> nodules on the thyroid. The largest being .8 x .6, although they didn't

> tell me what kind of measurement that is.

Usually in centimeters.

> ...I did some reading about the nuclear Thyroid scan and it

> seems to involve more x-rays and radioactive iodine. I wonder if this

> test is necessary, since from what I've read a needle biopsy is usually

> used on suspect nodules, uless they are too small.

It is essential and not very invasive. Very low doses of iodine and

radiation are involved.

The biopsy will categorize the type of cells in the nodules. The scan is

necessary to show whether any cells have spread beyond the nodules. It

will also show the biochemical activity of the nodules, whether they

take up iodine and are actively producing hormones or not.

I believe with more than three nodules greater than 0.5 cm, you may need

thyroidectomy followed by radioactive iodine ablation to " mop up. " If

the biopsy shows the nodules are completely benign and contained, they

may opt for just treating the hormone issues. They will really need both

types of tests to reliably make that decision.

Chuck

=

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Well thanks for answering the question I asked in the last e-mail, which hasn't

shown up here yet. I guess I should get the name of the radiologist who will

administer the test, verify board certification, and move forward?

Barb

Re: More Info

On 10/26/2010 2:16 PM, Roni Molin wrote:

> I would strongly recommend NOT getting any type of nuclear or other

> radiation testing. Instead ask for an MRI which is excellent at showing

> soft tissue in the body. I would not

> want to irradiate any nodules which might excite them to start growing....

The iodine scan will not use anywhere near enough iodine to risk that.

It is below the RDA. It will also show some critical potentialities that

the MRI cannot do.

We recently went through this with my son and all the arguments pro and

con. The endos won. :)

Chuck

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Thanks Chuck.

In a message dated 10/27/2010 6:47:27 P.M. Eastern Daylight Time,

gumboyaya@... writes:

Barb,

You wrote:

>

> Thanks for your opinion Chuck. So, if I'm understanding you right, the

> MRI will not reveal everything that needs to be known?...

It can visualize tumor boundaries, which could guide the surgeon.

However, ultrasound can do that more cheaply.

> ... Is there a

> possibility that if the nodules are benign, this test could activate

> them and make them malignant?...

No, malignancy is a multi-step process. A truly benign nodule is not

waiting for a dietary level of iodine, even radioactive iodine, to

trigger a change to malignancy. The dosage (and radiation exposure)

involved in ablation is a different story. There is some increase in

risk from that sort of dose, but since almost of it is concentrated in

the thyroid, most of the risk is destroyed along with the tissue.

Surrounding tissue is relatively safe, unless you have already had

nuclear procedures or an unusual amount of diagnostic exposure.

This is not to say that a benign growth cannot become malignant. I am

just saying a dietary level of iodine isn't going to cause it, even if

it is slightly radioactive.

Chuck

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On 10/27/2010 7:55 AM, Roni Molin wrote:

> I know what you're saying, it's still possible since we all react

> differently. Some people's thyroids

> react to the iodine in a CT scan and some don't.

It's not a CT, but a gamma spec camera. The amount of iodine used is

truly tiny, less than the RDA. All they do with it is trace where it

ends up, whether the nodules take up more or less than the surrounding

tissue.

When they use an iodine based dye injected for a CT scan, it is not

radioactive, but the radiation opaque chemicals do cause reactions, some

severe. I suspect you are thinking of this radio-opacity rather than

radioactive iodine.

>

> One question I do have about the needle biopsy, could this procedure

> precipitate any leaks of

> cells into the surrounding area while withdrawing the needle or even

> with the initial penetration?

In principle, yes, but the technique is designed to minimize the risk by

aspirating while penetrating, so everything that is loosened gets

vacuumed out with the blood. Our big concern with Mike was that every

needle biopsy would require he spend a week fighting the protocol to

remove and then restore his blood thinners. We decided to just go ahead

and do the thyroidectomy. In hindsight, this was a good move, since his

nodules were malignant.

The radioactive iodine used for the ablation is much greater than that

for the scan. I could barely detect the signal from Mike's earlier scan,

but the ablation dose pegged my meters for over a week. I have fairly

sensitive meters. :)

I could still detect his thyroid two weeks after the ablation when they

checked for any spread and found none.

Chuck

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