A future cure for Premature Ejaculation?

[Guest guest]

The company that makes the THT, I use are in trial studies that can

help the fight against premature ejaculation. I don't know if

pagaclone is on the open market, but I will research further.

PREMATURE EJACULATION

In reviewing the pagoclone database, the Company identified a small

number of patients who reported delayed ejaculatory response in

clinical trials. Based on this finding, in March 2006, the Company

filed anew patent application for the use of pagoclone as a treatment

for premature ejaculation. Additional testing is necessary to

determine whether pagoclone would be an effective treatment for PE,

and the Company is evaluating the clinical and regulatory path to

proof of concept studies of pagoclone as an on-demand oral therapy for

men with PE.

The normal ejaculatory response is controlled by multiple

neurotransmitters, including serotonin and GABA. There is evidence

that drugs that stimulate or increase the action of GABA in the brain

ay delay the ejaculatory response. Premature ejaculation is one of

the most common sexual dysfunctions in men, affecting approximately

30% of the adult male population. Currently, there is no FDA-approved

drug therapy for PE.

http://www.indevus.com/product/pagaclone.asp?page=pagaclone