a question about non-infectious theories

[Guest guest]

Sorry if this seems like a naive question, but it's something I've been

wondering about and haven't yet come across any good reasoning...

How do the traditional non-infectious theories about autoimmune diseases attempt

to explain the localized nature of many of them? If a person's immune system

did indeed decide (for whatever reason) that joint tissue itself was the enemy,

why would it choose to attack only certain joints and not others at any given

time? And how is it that inflamed areas can " spread " from place to place in/on

the body over time if there isn't some (thus far undiscovered) local causative

factor provoking the reaction? One would expect a truly haywire immune system

to see all connective tissue of a certain type as a threat and to attack it all

over the body at once, not just in certain places.

Any ideas or opinions?

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