Re: Re: Actos vs Glucophage?

March 21, 2001

In a message dated 3/21/01 10:54:38 AM Eastern Standard Time, maryato@...

writes:

<< Glucophage actually helps weight loss because of it's characteristic

of quickly slowing down the liver's dumping of glucose into the

bloodstream (less blood glucose = less potential glucose to be stored

as fat).

Actos actually slows down the liver, too, but Actos is slower

acting...it takes 2 to 4 or more weeks for it to become fully active

in your body.

>>

How concerned should i be about how much Glucophage does to my liver?

Does Actos cause any liver damage?

I just lost a friend, to liver failure, (he was diabetic and had AIDS, and

his HIV meds did it) I'd hate to have liver problems cuz of meds i'm taking

to make me feel better.

March 21, 2001

In a message dated 03/21/2001 9:54:53 AM Central Standard Time,

maryato@... writes:

<<

Anway, Glucophage and Actos (or Avandia, a drug similar to Actos) can

work well together as an additive affect.

T

>>

Thanks for the information. I am one of those few people who develop

acidosis on glucophage so am looking into Actos to increase my sensitivity.

Appreciate your information

ressy

March 21, 2001

T. ahhhhh I don't want to gain any more weight. He just put me on actos

yesterday and my blood sugars have gone nuts, i was in the 300 and above till

bed time and finally got it to 243, this am woke up to 165 had nothing to eat

since 6pm last night when the lab tec took my bg and checked my glucometer i was

back up to 189, please whats up with that. i still have not eaten today and

really don't want to.

glenna

http://www.geocities.com/barnie_64/FAMILY.html

Re: Actos vs Glucophage?

In addition to Meenie's comments, I don't have a sense of " Actos vs.

Glucophage. " They're both good drugs. As she said, some people have

severe gastrointestinal side effects from Glucophage. Peole nearly

always tolerate Actos pretty well. The official list of side affects

for Actos is that it is known to be associated with edema and weight

gain when you start taking it.

The potential weight gain happens as insulin has become more

effective and blood sugars have come down. High blood sugars are

associated with weight loss, because sugar is being excreted via

urine instead of being stored or used in the body. So when blood

sugars come down there can be a small initial weight gain, usually if

you are eating a substantial amount of calories.

Another thing that accounts for the gain of a few pounds is that if

you are storing glycogen in your muscles more efficiently (due to

improvements in insulin sensitivity), your water weight will go up a

little. This is the REVERSE affect of the common experience of going

on a diet, especially a low carb diet, and losing a lot of weight

quickly. When you suddenly reduce carbs and/or calories, there is an

initial water weight loss as you become depleted of muscle (and

liver) glycogen. This is because water is always used to store and

maintain glycogen.

Glucophage actually helps weight loss because of it's characteristic

of quickly slowing down the liver's dumping of glucose into the

bloodstream (less blood glucose = less potential glucose to be stored

as fat).

Actos actually slows down the liver, too, but Actos is slower

acting...it takes 2 to 4 or more weeks for it to become fully active

in your body.

Anway, Glucophage and Actos (or Avandia, a drug similar to Actos) can

work well together as an additive affect.

T

March 21, 2001

Glenna Donnelly wrote:

<< He just put me on actos yesterday and my blood sugars have gone nuts, i

was in the 300 and above till bed time and finally got it to 243, this am

woke up to 165 had nothing to eat since 6pm last night when the lab tec took

my bg and checked my glucometer i was back up to 189, please whats up with

that. i still have not eaten today and really don't want to. >>

Aaahhh crap, Glenna! I really sympathize with you! Do you think it's

possible you're moving to type 1 status? None of us type 2's has a lock on

that particular status.

Susie

March 21, 2001

Don't know but right now just trying to keep from geting depressed about it.

listoning to up beat music, this is really bugging the crap out of me

i told my doc. if they don't get the insulin inhaler here soon i am moveing to

canida. i am tired of fighting the fight right now. the shots the bg tests the

whole bit, i do just want to be normal, and it just ain't happening. i see my

mother, she is a over 300lb 5ft,5in person who in the past 2yrs has went down

hill by just sitting and eating i have to watch every bit of food i but in my

mouth. i hate it. and now i try and get help and it back fires. i am so tired of

people my dr.s thinking i am lies about what i eat. my system is so screwed up.

i just don't know. and moms lipids and her test all come back normal, i am very