Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 In a message dated 03/23/2001 8:27:40 AM Central Standard Time, ottercritter@... writes: << How about looking into Actos? Lots of good things about it recently in the group. >> Does Actos have the side effect of the lactic acidosis?? I have read the notes with interest also. ressy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 Thanks for the info , My kidney tests are all normal and I have liver functions done every 3 months as I am on lipitor. I am very senstive to meds so it does not surprise me that I had the reaction that I did with the glucophage....bradycardia with a sense of chest heaviness.....and that was on 1/4 of one pill....and on the first day also. So you can understand that I am very worried about new drugs in my system. Along with being sensitive I get great responses from drugs in tiny doses. On 5 mg of lipitor for 2 weeks my total cholesterol dropped 100 points. I also get great relief from cold symptons on medicine for children......I am so wierd. The pharmacist and the doc both know this so I am always started out on 1/4 doses of the smallest pill available thanks for responding ressy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 Dear Ressy, I'm sure as heck no doctor or expert, but I'm troubled by the nature of Starlix, since it seems to be a " short-term sulfonylurea. " The whole point of long-lasting good control for insulin-resistant type 2's is to rest our pancreas beta cells and improve our insulin sensitivity. It strikes me that Starlix (as was the case with sulfonylureas) goes about treating the diabetes the wrong way. It pummels the pancreas to churn out more insulin. This can help us nail the numbers - for NOW - but it would seem to shorten the live of our pancreas. The more we can baby our beta cells, the better off we should be ... in the long run. How about looking into Actos? Lots of good things about it recently in the group. Susie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 Ressy wrote, > Does Actos have the side effect of the lactic acidosis?? I have read the > notes with interest also. No, but lactic acidosis usually only happens with...I'm not sure...kidney or liver dysfunctions. If you have a bad liver they might not want to prescribe it because an earlier drug in the same class as Actos messed up livers big-time and had to be taken off the market (Rezulin...troglitazone). They've been very careful with Actos research and there's no sign it's got the same problem, but they still won't prescribe it if you have a liver dysfunction since Actos is fairly new. I think that the lactic acidosis goes with kidney problems, though...not sure. Best to check with your doctor on that. T Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 In a message dated 01-03-23 11:39:19 EST, you write: << I think that the lactic acidosis goes with kidney problems, though...not sure. Best to check with your doctor on that. >> I'm pretty sure the lactic acidosis has to do with liver problems. Vicki Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 resmith315@... wrote: > > Hey you guys I need some input here. My endo has prescribed me some of that > Starlix to help my spiking numbers. I am back to good numbers between 2 and > 3 hours but can reach 200 especially in the am....and that is just looking at > water sometimes....oh well > Anyway I had the glucophage once but had the lactic acidosis with it on a > very low dose so they don't want to do that again.... > I would like as much info about this and all you fine opinions if you could > please educate me. > thanks > ressy Been on Glucophage a few years, and all was pretty good except for my fasting readings, pp breakfast & dinner. Doc put me on NPH at bedtime and all is well. Also added some H for PP readings. Bedtime protein snack didn't do it for me. -- Dave - 9:28:07 AM T2 - 8/98 Glucophage, NPH, H - Davors Daily Aphorism: Hard work has a future payoff. Laziness pays off now. -- Visit my HomePage: http://dorcutt.homepage.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 Ressy, you might try insulin. It is generally as safe as any other med, if not safer. And It's a myth that it is necessarily permanent. It's often a very good beginning med -- it dosn't have to be a last resort. It can be used, for example, to get initial control by someone starting to cut carbs or a med that takes a while to work and who needs temporary help. Tom the actuary. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2001 Report Share Posted March 23, 2001 >Ressy, you might try insulin. It is generally as safe as any other med, >if not safer. And It's a myth that it is necessarily permanent. It's >often a very good beginning med -- it dosn't have to be a last resort. It >can be >used, for example, to get initial control by someone starting to cut carbs >or a med that takes a while to work and who needs temporary help. Well, but did you see the news account today that a study was done showing Type 2's who use insulin are worse off with cardiac function than Type 2's who stay on pills and diet and exercise only? Made me wonder, but then ... since mostly Type 2's aren't given insulin until they're way deep in complication territory, how do they know it's the *insulin that's causing the worse cardiac function? How do they know that it isn't years worth of high carb content on the old diet advice? Probably cause " they " don't yet know the true story of how carbs affect so many of us. Just food for thought. Another " bumped " one ... this time apparently banned for good without a word as to why. Again. jo mailto:jo_harper@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2001 Report Share Posted March 24, 2001 In a message dated 03/23/2001 11:24:40 PM Central Standard Time, jo_harper@... writes: << Another " bumped " one ... this time apparently banned for good without a word as to why. Again. jo >> Welcome to the club jo....feels like home huh!!! hehehe ressy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 26, 2001 Report Share Posted March 26, 2001 Tom the actuary wrote and Jo replied; > > >Ressy, you might try insulin. It is generally as safe as any other med, > >if not safer. And It's a myth that it is necessarily permanent. It's > >often a very good beginning med -- it dosn't have to be a last resort. It > >can be > >used, for example, to get initial control by someone starting to cut carbs > >or a med that takes a while to work and who needs temporary help. > > > Well, but did you see the news account today that a study was done showing > Type 2's who use insulin are worse off with cardiac function than Type 2's > who stay on pills and diet and exercise only? > The pro-insulin dialogs led to advice on getting insulin and syringes over the counter if the person's doctor was unwilling to prescribe. Boy, I do have a problem with that. I believe that if you disagree with your doctor's advice you should CHANGE DOCTORS, not self- medicate. There is a reason why the medical world is working so hard to develop new drugs that neither push the body to create more insulin nor make it necessary to take insulin. The reason is that INSULIN RESISTANCE which cause HYPERINSULINEMIA is the primary disease for many Type 2's. There is a strong school of thought now that insulin should not be increased unless it's clear that the person's pancreas is unable to create enough insulin. This is because EXCESSIVE insulin levels do indeed cause damage to the body, especially the heart and the vascular system. There just aren't any perfect, good, clear answers. Any treatment direction has its pros and cons. That's why I'd certainly want my caretakers, especially my doctor, to be " on board " and in support of anything I'm doing. What if you had a medical emergency, and your doctor was called in, unknowing that you were on insulin and assuming that you were controlled by other meds plus diet and exercise? This could be very bad. T Quote Link to comment Share on other sites More sharing options...
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