Quercetin: Human exposure to BPA 'grossly underestimated'

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From Pubmed via */bisphenol[tw] AND quercetin[tw]/*

The ameliorative effect of black tea extract and quercetin on bisphenol

A-induced cytotoxicity. <http://www.ncbi.nlm.nih.gov/pubmed/19226967>

Verma RJ, Sangai NP.

Acta Pol Pharm. 2009 Jan-Feb;66(1):41-4.

Sulfation of bisphenol A abolished its estrogenicity based on

proliferation and gene expression in human breast cancer MCF-7 cells.

<http://www.ncbi.nlm.nih.gov/pubmed/12206822>

Shimizu M, Ohta K, Matsumoto Y, Fukuoka M, Ohno Y, Ozawa S.

Toxicol In Vitro. 2002 Oct;16(5):549-56.

Relationship between estrogen receptor-binding and estrogenic activities

of environmental estrogens and suppression by flavonoids.

<http://www.ncbi.nlm.nih.gov/pubmed/12224631>

Han DH, Denison MS, Tachibana H, Yamada K.

Biosci Biotechnol Biochem. 2002 Jul;66(7):1479-87.

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EHP Study:

Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice:

Relevance for Human Exposure

<http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F\

10.1289%2Fehp.1002514>

A. , Frederick S. vom Saal, Wade V. Welshons, Bertram Drury,

Rottinghaus, A. Hunt, A. VandeVoort Online

20 Sep 2010

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News summary:

Study: Human exposure to BPA 'grossly underestimated.'

<http://www.nytimes.com/gwire/2010/09/20/20greenwire-study-human-exposure-to-bpa\

-grossly-underestima-4581.html>

By Gayathri Vaidyanathan Greenwire 21 September 2010

Americans are likely to be exposed at higher levels than previously

thought to bisphenol A, a compound that mimics hormones important to

human development and which is found in more than 90 percent of people

in the United States, according to new research. The new data indicate

people are likely exposed daily to an amount of BPA eight times higher

than the level EPA has judged safe. The study also gives the first

experimental support that some BPA is likely cleared at similar rates in

mice, monkeys and humans, making it possible to extrapolate health

studies in mice to humans.

more...

<http://www.nytimes.com/gwire/2010/09/20/20greenwire-study-human-exposure-to-bpa\

-grossly-underestima-4581.html>