Re: Kineret vs. Enbrel

March 4, 2006

I started Enbrel, was on it for a month, and had almost no resuts. I took my

first shot of Kineret, and noticed a change in 2 hours. I say skip the Enbrel.

morwyn42 wrote: Hi, all-

My rheumatologists both feel I should start an injection- but one

favors kineret and one favors enbrel. (I'm currently taking 15mg of

Prednisone a day & 15mg of Methotrexate.)

Do you guys have any opinions on which is best to start with? Or is it

kind of an individual case basis? Right now I'm favoring enbrel simply

because it's once a week. Seems less of a hassel. But if kineret is

really more likely to prevent a flare, that might be worth it...

Any info would be great, thanks!

~

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International Still's Disease Foundation is not engaged in rendering medical or

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or warranties with respect to any treatment, action, application, medication or

preparation by any person following the information offered or provided within

this support form.

ion by any person following the information offered or provided within this

support form.

March 4, 2006

Hi. Well, my son had his first flare last week since being diagnosed in Jan.

He has been on the max dose of medrol since then. The rheum is starting him on

kineret. We are waiting for insurance approval. I hope this doesn't take long.

He can't take methotrexate since his liver enzymes are elevated all the time and

his liver is still enlarged. For now he put him on voltaren while we wait for

the kineret to come through. I asked the same question about whether to take

enbrel or kineret and he feels the results have been very good so far with

kineret. Let' hope.

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March 4, 2006

I have not used Enbrel so I can't respond on that, but the daily injection

is not a big deal, no different than popping a pill. Kineret has been found

to do well in those with stills disease and of all the drugs in that class,

Kineret is the only one that does not raise your risk of lymphoma. That is

all I know.

Lynn

-- Kineret vs. Enbrel

Hi, all-

My rheumatologists both feel I should start an injection- but one

favors kineret and one favors enbrel. (I'm currently taking 15mg of

Prednisone a day & 15mg of Methotrexate.)

Do you guys have any opinions on which is best to start with? Or is it

kind of an individual case basis? Right now I'm favoring enbrel simply

because it's once a week. Seems less of a hassel. But if kineret is

really more likely to prevent a flare, that might be worth it...

Any info would be great, thanks!

~

Visit the Still's Disease Message Board

http://disc.server.com/Indices/148599.html

The materials and information contained in this message are not intended to

replace the services of a trained health professional or to be a substitute

for medical advice of physicians and/or other health care professionals. The

International Still's Disease Foundation is not engaged in rendering medical

or professional medical services. You should consult your physician on

specific medical questions, particularly in matters requiring diagnosis or

medical attention. The International Still's Disease Foundation makes no

representations or warranties with respect to any treatment, action,

application, medication or preparation by any person following the

information offered or provided within this support form.

ion by any person following the information offered or provided within this

support form.

March 4, 2006

Hm, I've kinda got insurance concern too. I have two different doctors

because two different insurance providers (through my school, UCLA,

and through my dad's work, Kaiser) and it's the one with the

significantly better drug coverage (Kaiser) who favors enbrel, so I'll

have to talk him into kineret if I want it. Not sure how that'll go.

(I've been pretty symptom-free for a few months, which is why I'm

equivocating rather than being like, " Give me drugs NOW! " which is my

general statement while having a flare. So it's mostly a question of

whether one is more likely to *prevent* a flare.)

I don't comment much, but I did see some of your earlier messages. I'm

so sorry for your son! I had my first flare December of my senior year

(2001) and it was just... very vexing, having to miss out on

activities and friends and being normal. And now in college I have to

be careful and responsible for all this stuff my peers don't and am

always worried about getting sick and missing a quarter and going

home. And I have this little mini-pharmacy in the corner of my

apartment and it's, somewhat ironically, right next to my roommates'

mini-bar and sometimes I look at the juxtaposition and think, " Well,

this isn't what I expected. "

What is voltaren? It's just a bridging drug, I gather, not an alternative?

I really hope your insurance comes through for the kineret! It's bad

enough not being sure what to do, but knowing and not being able to is

just... hellish.

~

>

> Hi. Well, my son had his first flare last week since being

diagnosed in Jan. He has been on the max dose of medrol since then.

The rheum is starting him on kineret. We are waiting for insurance

approval. I hope this doesn't take long. He can't take methotrexate

since his liver enzymes are elevated all the time and his liver is

still enlarged. For now he put him on voltaren while we wait for the

kineret to come through. I asked the same question about whether to

take enbrel or kineret and he feels the results have been very good so

far with kineret. Let' hope.

>

> ---------------------------------

> Yahoo! Mail

> Use Photomail to share photos without annoying attachments.

>

March 5, 2006

,

I have been on three of biologic response modifier drugs so far...Enbrel,

Remicade and now Kineret. I like the kineret best, although it requires more

injections (daily). I remembered my doctor telling me that I had to have failed

on another DMARD first, before Kineret....so I went to their website and copied

this info for you...

Kineret® (anakinra) is indicated for the reduction in signs and symptoms and

slowing the progression of structural damage in moderately to severely active

rheumatoid arthritis, in patients 18 years of age or older who have failed 1 or

more disease-modifying antirheumatic drugs (DMARDs). Kineret® can be used alone

or in combination with DMARDs other than tumor necrosis factor (TNF) blocking

agents.

Hope this helps

Stay Healthy

#1

morwyn42 wrote: