Guest guest Posted July 30, 2010 Report Share Posted July 30, 2010 Public FAQs Q: What is Sorbitol and Why Is It Used In AORs Capsules? A: Sorbitol, also known as glucitol, is a highly ubiquitous and naturally-occurring substance found in everything from the biochemistry of the human body to apples to chewing gum. The latter of course contains the synthetic version, and in the supplement industry sorbitol is used in capsules, tablets and softgels. Its most common roles are that of a plasticizer (to reduce capsule brittleness and enhance stability) and as a humectant (to reduce long-term leakage). Sorbitol is one of the most effective and widely used substances in the world for these and other similar purposes, spanning the food, pharmaceutical, and natural supplement industries. It holds GRAS (Generally Recognized As Safe) status with the FDA in the United States and in Canada is listed on the Ministry of Health's list of Acceptable Non-medicinal Ingredients with a composition allowance of 90%, one of the highest of any non-medicinal ingredients. However, as of March of 2009, the capsules of AOR products will no longer contain sorbitol as a constituent. Next Article Taken from Web MD: Sugar-Free Sweeteners and Side Effects: Case Histories One patient, a 21-year-old woman, had unexplained diarrhea and abdominal pain for eight months. She reported an unintended weight loss of 24 pounds, weighing in at about 90 pounds. After she was asked about diet, she said she chewed sugar-free gum with sorbitol daily, taking in about 18 to 20 grams a day. One stick typically has 1.25 grams. Once she eliminated sorbitol from her diet, the gastrointestinal problems stopped and she gained back more than 15 pounds. The second patient, a 46-year-old man, had been hospitalized because of diarrhea and a weight loss of more than 48 pounds during the previous year. His blood work and other exams came back normal, but when asked about diet, he, too, reported excessive consumption of sorbitol. He chewed 20 sticks of sugar-free gum daily and also ate about 7 ounces of sweets daily, totaling about 30 grams of sorbitol. When he cut out the sorbitol, he gained back 11 pounds within six months and his diarrhea problems disappeared. The message for doctors, the authors conclude, is to inquire about dietary habits when a patient has unexplained weight loss. Sugar-Free Sweeteners and Side Effects: A Food Scientist's View Reports of side effects such as abdominal pain and diarrhea with high amounts of sorbitol consumption are nothing new, says Clemens, DrPH, a spokesman for the Institute of Food Technologists and professor of pharmacology and pharmaceutical sciences at the University of Southern California, Los Angeles. " The laxative effect is very well documented, " Clemens tells WebMD. " It could be these individuals [in the case histories] were particularly sensitive. " And they did consume excessive amounts, he notes. " We would not expect the average consumer to consume upwards of 20 sticks of gum a day. " " Sorbitol is not well absorbed, " Clemens says. As a result, excess water enters the gastrointestinal tract and diarrhea can occur. Those who rely on artificially sweetened products to help manage their diabetes or to reduce overall calories, he says, should use a variety of such products and consume them in moderation. Sorbitol is found in toothpastes as well as chewing gum and sweets.To read the full article go to this link. Cyndi B http://www.webmd.com/diet/news/20080110/sweetener-side-effects-case-histories Quote Link to comment Share on other sites More sharing options...
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