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Re: Blood type

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> -----Original Message-----

> Date: Friday, December 03, 1999 8:52 PM

> The rarer blood types seem to get transplanted sooner I guess

> because there is not as much competition.

> ...

> Peg

Peg, you are right that there is no competition for AB type

organs from other blood groups. A bigger factor is the

competition for O type livers from other blood groups. To limit

the competition, UNOS rules exclude transplanting O type livers

to non-O patients unless the recipient is Status 1.

If O livers always went to O patients, O blood types would have

a shorter wait than average because more donors are O type than

the general population.

Type % in pop. % donors, recipients, waiting(1997)

O 43 48.6 41.9 51.5

A 40 37.3 40.2 36.0

B 12 10.6 12.5 10.9

AB 5 3.6 5.4 2.7

I think that to some extent people with O type blood get the

message drilled into them that their blood (and organs) are more

important because they can be used by all blood types, so there

is always a push to get O types to donate. I believe that

attitude carries over to organ donation. Even with the higher

donation rates, O's have longer waits because 14% of the O

livers donated go to other blood groups for emergency

transplants.

Tim

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Tim,

I'm glad they are only using the O livers for O patients with the exception

of very ill almost dieing patients. It isn't fair that O patients should be

penalized for having the common blood type. We were told that because Phil

has type O he would have at least a 2 year wait. Since he isn't currently

ill other than the fatigue, we are too concerned at this point. The longer

he can wait, maybe to better results will be with less post transplant

complications. We are concerned about the cancer since it appears that he

has had this undiagnosed for a long time.

Peg

Romlein wrote:

> > -----Original Message-----

> > Date: Friday, December 03, 1999 8:52 PM

> > The rarer blood types seem to get transplanted sooner I guess

> > because there is not as much competition.

> > ...

> > Peg

>

> Peg, you are right that there is no competition for AB type

> organs from other blood groups. A bigger factor is the

> competition for O type livers from other blood groups. To limit

> the competition, UNOS rules exclude transplanting O type livers

> to non-O patients unless the recipient is Status 1.

>

> If O livers always went to O patients, O blood types would have

> a shorter wait than average because more donors are O type than

> the general population.

>

> Type % in pop. % donors, recipients, waiting(1997)

> O 43 48.6 41.9 51.5

> A 40 37.3 40.2 36.0

> B 12 10.6 12.5 10.9

> AB 5 3.6 5.4 2.7

>

> I think that to some extent people with O type blood get the

> message drilled into them that their blood (and organs) are more

> important because they can be used by all blood types, so there

> is always a push to get O types to donate. I believe that

> attitude carries over to organ donation. Even with the higher

> donation rates, O's have longer waits because 14% of the O

> livers donated go to other blood groups for emergency

> transplants.

>

> Tim

>

> __________________________________________________

>

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Dan,

When I saw your question I hoped I'd find a great explanation

from Aubrey getting me off the hook. But that wasn't to be :)

I based my statement on a discussion of screening donors for

blood type compatibility by Dr. Jeffery Punch on 07/08/1999 in

the TRNSPLNT forum, where he stated, " Note: the RH factor (+ or

-) does not matter at all. "

So the question still remains, why is this not a problem with

organ transplants while it is with blood transfusions. I have a

bare inkling, but not enough to give a coherent explaination.

Anyone else want to step forward?

Tim at the edge of his knowledge

--- Dan Bertles wrote:

> Tim,

>

> I'm really amazed that rh factor isn't an important

> consideration with

> liver transplants. Any explainations for this?

>

> Dan

>

> timothy romlein wrote:

> original

> article:/group//?start=7127

> (the Rh factor doesn't matter for organ transplant...

>

>

>

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> http://clickhere./click/1701

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> -- /vote?listname= & m=1

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>

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Rh factor and blood transfusions versus transplantation:

In the blood transfusion situation you will react immediately to blood

which has a different Rh factor on the surface of the cells transfused

because you aren't taking any immunosuppressant medications. This will

not happen in the transplant situation because you are being given

immunosuppressant medication. My impression is that the reaction is far

stronger if they give you incompatable tissue type, say an A liver into

a B person. Even with immunosuppressive medication this will be

difficult to counteract. This is one of the significant issues with

xenotransplantation. The cell surface antigens are very different in

animals versus humans. This is why they are adding human genetic markers

to animals in an attempt to get around this problem.

Aubrey

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