Decomposition of mycotoxins with bacteria

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Microbiologicals for deactivating mycotoxins

Schatzmayr, G., Zehner, F., Taubel, M., Schatzmayr, D., Klimitsch, A.,

Loibner, A. P. and Binder, E. M.

Molecular Nutrition & Food Research. 2006; 50(6): 543-551. Article. IF

2,071

Mycotoxins are secondary metabolites of fungi affecting human and

animal health. Five classes of mycotoxins are of major concern in

animal husbandry, namely aflatoxins, trichothecenes, zearalenone,

ochratoxins, and fumonisins. Due to their diverse structure these

fungal toxins are able to cause a great variety of acute symptoms in

animals. Clay minerals have been used in animal nutrition to bind

mycotoxins, but the binders are only very specific for aflatoxins but

not for other toxins. A novel strategy to control the problem of

mycotoxicoses in animals is the application of microorganisms capable

of biotransforming mycotoxins into nontoxic metabolites. The microbes

act in the intestinal tract of animals prior to the resorption of the

mycotoxins. A Eubacterium (BBSH 797) strain is able to deactivate

trichothecenes by reduction of the epoxide ring (CAST, Mycotoxins,

Risks in Plant, Animal and Human Systems, Task Force Report 139,

Council of Agricultural Science and Technology, Ames Iowa 2003, p.

10.; Binder, E. M., Binder, J., Ellend, N., Schaffer, E. et al., in:

Miraglia, M., van Egmond, H., Brera, C., Gilbert, J. (Eds.),

Mycotoxins and Phycotoxins - Developments in Chemistry, Toxicology and

Food Safety, Alaken, Fort 1996, pp. 279-285). This strain was

isolated out of bovine rumen fluid and the mode of action was proven

in vitro and also in vivo.

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I think this is very interesting. Do we have a farmer or someone who

knows someone with proper credentials, who would be able to obtain

this Eubacterium (BBSH 797) - the market name of the product is

Biomin? Then we could perform controlled experiments and estimate how

it would fare as far as decomposition of mycotoxins on common objects

is concerned.

Who knows, maybe it turns out to be our Holy Grail?