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While DDI/HU has very good activity against HIV, the risk of metabolic complications, pancreatitis, and death suggests that one should be very, very careful about considering this combination.On Aug 24, 2005, at 10:47 AM, PozHealth wrote:  This report  doesn't mention hydroxyurea,  but I've heard that it can double or even triple  the chances of getting  lactic acidosis from ddI.  Needless to say, I  never went back to either drug  after my necessary treatment interruption.  Barrowpozbod@...

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