article

[Guest guest]

July 31, 2002, 7:39PM

Schizophrenia drug seems to help autistic kids

Associated Press

A newer drug used to treat adults with schizophrenia also curtails serious

behavioral problems in children with autism, a study shows.

Older medications used to treat troublesome conduct can have severe side

effects. The research reported in today's New England Journal of Medicine is

the first large, controlled study in autistic children of a newer type of

antipsychotic drug with fewer adverse reactions.

The drug, Risperdal, was tested in 101 children with autism who had

aggressive behavior, temper tantrums or hurt themselves. Sixty-nine percent

of the children who took Risperdal showed a positive response by the end of

the eight-week test, compared with 12 percent of the children who were given

a dummy pill.

The drug, also known as risperidone, continued to be effective for six

months, said Lawrence Scahill of the Yale Child Study Center, the lead

author of the study done in five cities.

Risperdal is already used for children with autism, a brain disorder that

impairs development.

The researchers said Risperdal didn't cause the neurological side effects

associated with older drugs, such as awkward movements, stiffening of

muscles and restlessness.

Article

Did anyone happen to read the article in the Houston Chronicle today

about the new medication study they did on Children with Autisim that

is supposed to help w/ behaivor issues?

[Guest guest]

Are autistic children at greater risk for abuse?

Hallmarks of a developmental disorder create additional level of concern

By

Story updated at 10:18 AM on Tuesday, Apr. 7, 2009

Photos

Photo 1 of 2

RICK WILSON/The Times-Unionlyn Popp listens as her daughter, , plays a keyboard at their Avondale home.

RICK WILSON

Photo 2 of 2

RICK WILSON/The Times-Union Popp (left), who is 14 and autistic, sits nearby as her mother, lyn, discusses the challenges of raising an autistic child and their experiences in the Duval County public school system and at the Jericho School, where is now enrolled.

RICK WILSON

She was desperate to communicate what she wanted. So much so that the tiny girl would thrash around, throw herself on the floor and kick others in vain to express what she couldn't in words.

Autism stood like a wedge between Popp and the confusing world she inhabited. When she was old enough to attend public school, some teachers tried almost as hard as she did to get her to understand them. Once, her mother said recently, she came home bearing signs of a struggle.

The handprints on her back and pools of purple around her eyes conveyed what the girl could not.

"I knew there were things that were happening," said lyn Popp of Avondale, adding that she remains unsure eight years later which injuries were self-inflicted and which were not, except the handprints.

Many of the hallmarks of autism put children at risk of abuse, experts say. Children with autism have trouble deciphering what others are thinking and feeling, which may be frustrating to parents, teachers and others around them. More so than typical children, they take their cues from others and have difficulty distinguishing bad adult behavior from good. And if abuse occurs, communication impairments hamper their ability to tell someone.

Nearly one in five autistic children had been physically abused among a sample of 156 children with autism who had been taken to community health centers for treatment, according to a University of Pennsylvania study. About one in six had been sexually abused.

Those proportions were slightly lower than children with other mental health-related conditions but still high enough to shock the study's lead author.

"This was very striking to us," said Mandell, associate director for the Children's Hospital of Philadelphia's autism center. "I can understand people getting frustrated, but I find this behavior very inexcusable."

The 2005 study also laid bare the consequences of that abuse. The abused children were more likely to act out in sexual or abusive ways, attempt suicide or run into academic and conduct problems at school. Mandell said the research underscored the importance of vigilance on the part of therapists and doctors for signs of abuse.

"Kids with autism by definition have a problem communicating. It means you can't rely on a child's report. You need to do a physical exam and look for evidence of abuse. It means you have to have a difficult and challenging discussion with the caregiver," he said.

Abuse cases often more complex

Separate national advocacy camps have adopted the month of April as the peak of their public-relations campaigns. As a result, it is known alternately as National Autism Awareness Month and Child Abuse Prevention Month. Autism and child abuse, though, have more in common than a page on a calendar.

Abuse cases involving autism tend to be more complex than those involving other children.

The condition itself is complicated. It is widely known as autism spectrum disorders, or ASD, so named because it encompasses such developmental disorders as Asperger's syndrome, Rett syndrome and childhood disintegrative disorder. In general, autism is a brain disorder that begins in early childhood, usually by the age of 3, and is marked by an inability to have normal social interactions.

And many children with autism are diagnosed with more than one condition. Every child is different, with different needs, experts say.

Recent allegations lodged against a longtime ville special-education teacher offer a window into these complexities.

Rhona Milton was arrested on child abuse charges on March 17 and released from jail shortly afterward on her own recognizance. The 32-year teaching veteran stands accused of tying an autistic student to a toilet-training chair for hours over several days in September at Kernan Trail Elementary, according to police reports.

Two classroom aids and an intern also were in the room and told investigators the boy was forced to sit in the chair with his pants down from 9 a.m. until the end of the school day, save for a break at lunch. The staff members told police that Milton told them the boy was being potty-trained.

An arraignment has been scheduled for Wednesday.

The charges shocked ville's tight-knit community of parents with autistic children. A mother of a child with Asperger's and longtime friend of Silver's, for one, said she believes in the teacher's innocence.

"I know Rhona to be an intrepid advocate for people with autism spectrum disorders," said Delegal, noting Silver's leadership with an Asperger's support group and blemish-free teaching record. "I believe that the charge against her must be a terrible mistake."

A Duval County school autism expert told investigators that the chair at the center of the case, called a Rifton chair, wasn't required by any of the children in Silver's classroom. Ken Sutton, executive director of exceptional education, distributed a memo among the district's more than 150 schools a day after the arrest, calling on them to identify and "redeploy" any unnecessary specialized equipment.

"You can imagine we have a lot of inventory that is very expensive, and it would make sense if we could redeploy it where it's needed," Sutton said in an interview, adding that he had been drafting the policy before Silver's arrest.

The chair is not intended to be used for behavioral modification, he added.

A parent's concerns

On a Monday afternoon late last month, Popp sat on a squashy couch in her family's living room, fidgeting but calm. Suddenly, she announced she was cold.

"Do you want to play your piano?" asked her mother, who was seated beside her.

"No," replied reflexively, almost unconsciously.

With the word still hanging in the air, she walked into another room, where a keyboard sat on a wooden desk, and began flawlessly playing a tune she called "Birthday Party."

This, her mother would say later, is progress. After years of intensive, individualized instruction at an Arlington private school called the Jericho School, , now 14, has gotten the basics down: sitting in a chair, making snacks, shaking hands with visitors, among others.

The approach advocated by the school calls for a system of rewards for good behavior. As in playing the piano to get the thermostat turned up.

lyn Popp freely acknowledges that her daughter was once a "world-class" tantrum artist. Still, when came home from Pinedale Elementary one day in March 2001 with her eyes blackened and handprints on her back, Popp never sent her back to the school.

A Duval school system spokeswoman directed questions about the Popps' abuse claim to Sutton, who said he couldn't comment on it because the alleged event occurred years before he stepped into his current position.

A decade ago, Popp and her husband, , filed an unsuccessful federal lawsuit alleging the Duval school system was violating the law by not drafting and following individualized education plans for children with disabilities. Their 18-year-old son, , has a mild form of Asperger's and also attended schools in the system.

But observers say their fight laid the groundwork for a program that put Duval teachers in touch with autism experts.

Sutton, the exceptional student program head, said his teachers are more prepared than ever to handle children suffering from difficult disorders.

He pointed to a summer academy for both exceptional student teachers and other teachers held each of the last two years.

The program emphasizes positive behavioral support as opposed to using punitive measures while teaching children with developmental problems, he said.

Further, his department is set to receive $15 million soon and another $15 million in September in federal stimulus money. A "large amount" of that infusion will go toward professional training, Sutton said.

jeremy.cox@...,

[Guest guest]

FYI

Thanks!

 

Platner

 

Article

Odessa, TX - A drug on the market is helping reduce pre-term births, but it's

costing expectant mothers thousands of dollars more than it used to.

The drug called, Makena, is now the only drug of its kind approved by the

Federal Drug Administration, but the swift change in price is only causing

expecting mothers more stress.

Trisha Weatherford is 29 weeks pregnant, but after losing her first, born

premature this is a high-risk pregnancy.

" He lived 22 minutes, died in my arms, you don't get over that. "

For her second pregnancy she's now using a drug called 17-hydroxyprogesterone, a

weekly shot that keeps her uterus calm and the baby at bay.

But the drug, recently approved by the FDA, is now called Makena and went from

costing $10 to $20 a dose, to $1,500 a dose.

" The day I found out about it, I was just mad. " Weatherford quickly stocked up

on the last seven doses she needed, before the price changed.

Her obstetrician, Dr. D. Blanco, was also shocked after prescribing the

drug for two years.

" I couldn't understand why that was happening, nothing had changed, the drug's

been available at a very low price, so how can it be that all the sudden it

became expensive to manufacture the drug? "

The medicine is needed once a week for 20 weeks, the new price will cost up to

$30,000 for one pregnancy.

" It's very unlikely at that price that any insurance or any Medicaid program is

going to cover this, " Blanco said.

Making the drug almost inaccessible to many women.

" It will result in babies being born earlier than they should, babies that will

die and babies that will be sick. "

The maker of Makena, KV Pharmaceutical, posted a response on their website,

click here to see it.

For Information on prenatal care click here.