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Isotretinoin and Vitex

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Can anyone advise whether a patient can continue taking Vitex FE (10 gtt mane)

whilst taking oral isotretinoin for acne? I cannot find a reference stating that

this treatment would be contraindicated.

Many thanks

Janette

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Dear Janette,

I quote from the 2001 edition of Herb contraindications and Drug interactions

1)

Isotretinoin and Vitex

Can anyone advise whether a patient can continue taking Vitex FE (10 gtt mane)

whilst taking oral isotretinoin for acne? I cannot find a reference stating that

this treatment would be contraindicated.

Many thanks

Janette

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Dear Janette

continue what I stared this morning and which was sent to you before completion.

Vitex

1)'may interfere with the efficacy of birth control pills, progesterone drugs or

HRT due to its hormone regulating activity (speculative)

2) dopamine antagonists may be weakened(speculative) due to its dopaminergic

effects(in animals) as shown by the antagonism of haloperidol to the

dopamine-induced prolactin inhibition caused by the ethanolic extract (in vitro)

The only other cautions in this book are for pregnancy and breast feeding.

If I remember correctly Des Corrigans book on vitex does not mention any herb

drug interactions but I can not be sure on that one.

ri

Isotretinoin and Vitex

Can anyone advise whether a patient can continue taking Vitex FE (10 gtt mane)

whilst taking oral isotretinoin for acne? I cannot find a reference stating that

this treatment would be contraindicated.

Many thanks

Janette

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