Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 Hi Ann, Sorry you are feeling so poorly. I am glad you are checking this out with your dr. Here is a link re dapsone: http://www.dermnetnz.org/treatments/dapsone.html <<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips. Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patients receiving dapsone; it is usually mild. It is possibly less likely if you are taking antioxidants such as ascorbic acid (vitamin C) or cimetidine tablets. Possible symptoms of anaemia include tiredness and shortness of breath. More severe anaemia is likely if you have a rare condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarely associated with potentially fatal severe drug hypersensitivity syndrome, in which there is prolonged rash, fever, swollen lymph glands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur, particularly with long term dapsone therapy with doses greater than 100 mg per day. Once per week it is advisable to test your ability to walk on your " tip-toes " and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported. Rare, but potentially serious side effects * A significant decrease in the white blood count typically presents with fever, sore throat, skin infections, or other local signs of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causing severe fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur. Usually, a blood test is performed as a base-line before starting dapsone. It is then checked after about a week on therapy, and then about once a month, depending on the dose and state of the blood count. >> Please let us know what your dr. thinks. I'd give you a better answer if I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 Hi Ann, Sorry you are feeling so poorly. I am glad you are checking this out with your dr. Here is a link re dapsone: http://www.dermnetnz.org/treatments/dapsone.html <<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips. Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patients receiving dapsone; it is usually mild. It is possibly less likely if you are taking antioxidants such as ascorbic acid (vitamin C) or cimetidine tablets. Possible symptoms of anaemia include tiredness and shortness of breath. More severe anaemia is likely if you have a rare condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarely associated with potentially fatal severe drug hypersensitivity syndrome, in which there is prolonged rash, fever, swollen lymph glands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur, particularly with long term dapsone therapy with doses greater than 100 mg per day. Once per week it is advisable to test your ability to walk on your " tip-toes " and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported. Rare, but potentially serious side effects * A significant decrease in the white blood count typically presents with fever, sore throat, skin infections, or other local signs of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causing severe fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur. Usually, a blood test is performed as a base-line before starting dapsone. It is then checked after about a week on therapy, and then about once a month, depending on the dose and state of the blood count. >> Please let us know what your dr. thinks. I'd give you a better answer if I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 Hi Ann, Sorry you are feeling so poorly. I am glad you are checking this out with your dr. Here is a link re dapsone: http://www.dermnetnz.org/treatments/dapsone.html <<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips. Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patients receiving dapsone; it is usually mild. It is possibly less likely if you are taking antioxidants such as ascorbic acid (vitamin C) or cimetidine tablets. Possible symptoms of anaemia include tiredness and shortness of breath. More severe anaemia is likely if you have a rare condition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarely associated with potentially fatal severe drug hypersensitivity syndrome, in which there is prolonged rash, fever, swollen lymph glands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur, particularly with long term dapsone therapy with doses greater than 100 mg per day. Once per week it is advisable to test your ability to walk on your " tip-toes " and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported. Rare, but potentially serious side effects * A significant decrease in the white blood count typically presents with fever, sore throat, skin infections, or other local signs of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causing severe fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur. Usually, a blood test is performed as a base-line before starting dapsone. It is then checked after about a week on therapy, and then about once a month, depending on the dose and state of the blood count. >> Please let us know what your dr. thinks. I'd give you a better answer if I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 After 3 months of trial and error treatments for my pg I was prescribed DAPSONE. I lived a ways out of town and was only seeing a doc once a week or so. they didn't tell me much about the drug except that i would be taking it for a couple of months at least, and that it was used to treat leprocy patients with success. by this point my faith in modern medicine was at best ...skeptical, so i immediately began researching the drug (online), and what i found out was "the straw that broke the camels back"!! there were enough side effects, some of them, with certain conditions were severe, and I came to the conclusion that this is a drug that should not be taken lightly, and should be taken only in a situation where daily monitoring and blood work could be done!! IN my situation ( once a week visits to town) dapsone was a (in my opinion) a very irrisponsible choice of treatments Anyway , dapsone is definately one of those drugs that ( the benefits must out weigh the possible side effects) , and unless your doc is WAY familiar with your case history, and your condition , i would question it being prescribed. JUST A THOUGHT... SHANE J MABERRY Re: Umm/Dapsone Hi Ann,Sorry you are feeling so poorly.I am glad you are checking this out with your dr. Here is a link redapsone:http://www.dermnetnz.org/treatments/dapsone.html<<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips.Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patientsreceiving dapsone; it is usually mild. It is possibly less likely ifyou are taking antioxidants such as ascorbic acid (vitamin C) orcimetidine tablets. Possible symptoms of anaemia include tiredness andshortness of breath. More severe anaemia is likely if you have a rarecondition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarelyassociated with potentially fatal severe drug hypersensitivitysyndrome, in which there is prolonged rash, fever, swollen lymphglands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur,particularly with long term dapsone therapy with doses greater than100 mg per day. Once per week it is advisable to test your ability towalk on your "tip-toes" and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported.Rare, but potentially serious side effects * A significant decrease in the white blood count typicallypresents with fever, sore throat, skin infections, or other localsigns of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causingsevere fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur.Usually, a blood test is performed as a base-line before startingdapsone. It is then checked after about a week on therapy, and thenabout once a month, depending on the dose and state of the blood count. >>Please let us know what your dr. thinks. I'd give you a better answerif I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 After 3 months of trial and error treatments for my pg I was prescribed DAPSONE. I lived a ways out of town and was only seeing a doc once a week or so. they didn't tell me much about the drug except that i would be taking it for a couple of months at least, and that it was used to treat leprocy patients with success. by this point my faith in modern medicine was at best ...skeptical, so i immediately began researching the drug (online), and what i found out was "the straw that broke the camels back"!! there were enough side effects, some of them, with certain conditions were severe, and I came to the conclusion that this is a drug that should not be taken lightly, and should be taken only in a situation where daily monitoring and blood work could be done!! IN my situation ( once a week visits to town) dapsone was a (in my opinion) a very irrisponsible choice of treatments Anyway , dapsone is definately one of those drugs that ( the benefits must out weigh the possible side effects) , and unless your doc is WAY familiar with your case history, and your condition , i would question it being prescribed. JUST A THOUGHT... SHANE J MABERRY Re: Umm/Dapsone Hi Ann,Sorry you are feeling so poorly.I am glad you are checking this out with your dr. Here is a link redapsone:http://www.dermnetnz.org/treatments/dapsone.html<<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips.Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patientsreceiving dapsone; it is usually mild. It is possibly less likely ifyou are taking antioxidants such as ascorbic acid (vitamin C) orcimetidine tablets. Possible symptoms of anaemia include tiredness andshortness of breath. More severe anaemia is likely if you have a rarecondition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarelyassociated with potentially fatal severe drug hypersensitivitysyndrome, in which there is prolonged rash, fever, swollen lymphglands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur,particularly with long term dapsone therapy with doses greater than100 mg per day. Once per week it is advisable to test your ability towalk on your "tip-toes" and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported.Rare, but potentially serious side effects * A significant decrease in the white blood count typicallypresents with fever, sore throat, skin infections, or other localsigns of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causingsevere fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur.Usually, a blood test is performed as a base-line before startingdapsone. It is then checked after about a week on therapy, and thenabout once a month, depending on the dose and state of the blood count. >>Please let us know what your dr. thinks. I'd give you a better answerif I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 After 3 months of trial and error treatments for my pg I was prescribed DAPSONE. I lived a ways out of town and was only seeing a doc once a week or so. they didn't tell me much about the drug except that i would be taking it for a couple of months at least, and that it was used to treat leprocy patients with success. by this point my faith in modern medicine was at best ...skeptical, so i immediately began researching the drug (online), and what i found out was "the straw that broke the camels back"!! there were enough side effects, some of them, with certain conditions were severe, and I came to the conclusion that this is a drug that should not be taken lightly, and should be taken only in a situation where daily monitoring and blood work could be done!! IN my situation ( once a week visits to town) dapsone was a (in my opinion) a very irrisponsible choice of treatments Anyway , dapsone is definately one of those drugs that ( the benefits must out weigh the possible side effects) , and unless your doc is WAY familiar with your case history, and your condition , i would question it being prescribed. JUST A THOUGHT... SHANE J MABERRY Re: Umm/Dapsone Hi Ann,Sorry you are feeling so poorly.I am glad you are checking this out with your dr. Here is a link redapsone:http://www.dermnetnz.org/treatments/dapsone.html<<Side effects: minor, relatively infrequent * Gastrointestinal upset including nausea or vomiting. * Headache. * Blue discolouration of lips and fingertips.Side effects of greater importance * Anaemia (low haemoglobin or blood count) is common in patientsreceiving dapsone; it is usually mild. It is possibly less likely ifyou are taking antioxidants such as ascorbic acid (vitamin C) orcimetidine tablets. Possible symptoms of anaemia include tiredness andshortness of breath. More severe anaemia is likely if you have a rarecondition known as glucose-6-phosphate dehydrogenase (G6PD) deficiency. * Allergy may cause a widespread skin rash. It is rarelyassociated with potentially fatal severe drug hypersensitivitysyndrome, in which there is prolonged rash, fever, swollen lymphglands and internal organ failure (liver, lungs, heart, kidneys). * Uncommonly, weakness of the foot and hand muscles can occur,particularly with long term dapsone therapy with doses greater than100 mg per day. Once per week it is advisable to test your ability towalk on your "tip-toes" and to test your hand grip strength. * Rarely, psychosis (hallucinations or delusions) has been reported.Rare, but potentially serious side effects * A significant decrease in the white blood count typicallypresents with fever, sore throat, skin infections, or other localsigns of infection. Commonly a widespread red skin rash is also present. * Rarely, an illness resembling glandular fever develops, causingsevere fatigue, fever, sore throat, rash and prominent lymph glands. * Tell your doctor promptly if these symptoms occur.Usually, a blood test is performed as a base-line before startingdapsone. It is then checked after about a week on therapy, and thenabout once a month, depending on the dose and state of the blood count. >>Please let us know what your dr. thinks. I'd give you a better answerif I knew it. Not many in the group have reported taking dapsone. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 I agree with you Shane, and found a link that does question Dapsone: http://www.hotkey.net.au/~marshalle/dapsone1/dapsone2.htm <<They recall being ordered under threat of court martial to take dapsone, traditionally a leprosy drug with a risk of suppressing bone marrow production, but say they were never told they were part of a trial. They fear that the suppression of bone marrow production may have seriously reduced their immunity to infections, possibly compounding toxic effects of defoliants such as Agent Orange. >> This is not a medical link, but I think it does show that the question of Dapsone and immunity impairment has been questioned, perhaps with good cause. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 I agree with you Shane, and found a link that does question Dapsone: http://www.hotkey.net.au/~marshalle/dapsone1/dapsone2.htm <<They recall being ordered under threat of court martial to take dapsone, traditionally a leprosy drug with a risk of suppressing bone marrow production, but say they were never told they were part of a trial. They fear that the suppression of bone marrow production may have seriously reduced their immunity to infections, possibly compounding toxic effects of defoliants such as Agent Orange. >> This is not a medical link, but I think it does show that the question of Dapsone and immunity impairment has been questioned, perhaps with good cause. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 I agree with you Shane, and found a link that does question Dapsone: http://www.hotkey.net.au/~marshalle/dapsone1/dapsone2.htm <<They recall being ordered under threat of court martial to take dapsone, traditionally a leprosy drug with a risk of suppressing bone marrow production, but say they were never told they were part of a trial. They fear that the suppression of bone marrow production may have seriously reduced their immunity to infections, possibly compounding toxic effects of defoliants such as Agent Orange. >> This is not a medical link, but I think it does show that the question of Dapsone and immunity impairment has been questioned, perhaps with good cause. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2006 Report Share Posted February 16, 2006 shane, i appreciate your comments about dapsone, but as you know, there are 2 sides to every story. dapsone is one of the few successful treatments for pg. i could list all the rx's i have had and had some pretty severe effects i might add, but i would run out of space in this reply. you are right, you have to weigh the benefits vs the potental issues. but i can tell you what, i don't think it is any docs fault for trying to find the cure for the person they are treating. everyone is different, just look at your case study. mine is different from anyone elses as well. there is a certain degree/level of " experimentation " that goes on and i don't think a doc can always protect you from that. why do you think they are so careful about getting you medical history and keeping it updated? we just don't know enough about this disease and we certainly don't have treatments that are " cut and dry " . i have discussed several times with, really, pretty good docs (some are researchers), that the treatment many times with autoimmune disease is worse than the disease itself. i know you had bum experiences with docs, i have too, but they are not all like that. even the good docs, you have to give them some breathing room. i think it is the patient's responsibility to train themselves so they are prepared to work with their doc. how much can a tax accountant help you if you didn't do your homework, keep good records and bring them to your accountant? it is a 2 way street. i write this because people need to keep their options open. i take a low dose chemo drug, called methotrexate. guess how many nasty things i have heard about that? then my remicade. same there. i have talked with people that have had some pretty nasty experiences with these 2 drugs. but after taking and experimenting with many things, it settled out using these and they have been extremely helpful to me. it gave me my life back. dunno, just me 2 cents. jeff > > After 3 months of trial and error treatments for my pg I was prescribed DAPSONE. I lived a ways out of town and was only seeing a doc once a week or so. they didn't tell me much about the drug except that i would be taking it for a couple of months at least, and that it was used to treat leprocy patients with success. > by this point my faith in modern medicine was at best ...skeptical, so i immediately began researching the drug (online), and what i found out was " the straw that broke the camels back " !! there were enough side effects, some of them, with certain conditions were severe, and I came to the conclusion that this is a drug that should not be taken lightly, and should be taken only in a situation where daily monitoring and blood work could be done!! > IN my situation ( once a week visits to town) dapsone was a (in my opinion) a very irrisponsible choice of treatments > Anyway , dapsone is definately one of those drugs that ( the benefits must out weigh the possible side effects) , and unless your doc is WAY familiar with your case history, and your condition , i would question it being prescribed. > JUST A THOUGHT... > > SHANE J MABERRY Quote Link to comment Share on other sites More sharing options...
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