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Nutritional therapy in metabolic changes in individuals with HIV/AIDS

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[Nutritional therapy in metabolic changes in individuals with HIV/AIDS.][Article in Portuguese]Falco M, Castro AD, Silveira EA.SourcePrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Universidade Federal de Goiás. Goiânia, Goiânia, GO, Brasil.AbstractOBJECTIVE:To analyze the effect of nutritional treatment on metabolic changes caused by the use of antiretroviral therapy in adults with HIV/AIDS.METHODS:A systematic review of literature was conducted in the PubMed, Lilacs and Cochrane databases, between 1996 and 2010, including crossover and randomized controlled clinical trials performed in adults

with HIV/AIDS using antiretroviral therapy and without opportunistic diseases. The intervention of interest was oral nutritional supplementation and/or a change in lifestyle due to specific dietary treatment: dyslipidemia, insulin resistance, lipodystrophy and systemic arterial hypertension. The Jadad scale was used for a qualitative classification of articles.RESULTS:A total of 385 articles were found, of which seven were included. The interventions used in these studies were as follows: diet, diet and physical exercises, diet and supplementation, and only supplementation. Dyslipidemia was the outcome assessed in all studies. Studies that assessed omega-3

supplementation found a significant reduction in triglycerides. The specific diet with omega-3 supplementation showed an increase in HDL-cholesterol. Chrome nicotinate supplementation did not have an effect on dyslipidemia. Changing one's lifestyle, including diet and physical activity, significantly reduced waist circumference, lipodystrophy and systolic blood pressure.CONCLUSIONS:Reduction in tryglicerides with omega-3 supplementation was the nutritional intervention with the strongest scientific evidence. Prescribing a specific diet appeared to be the most adequate intervention to increase HDL-cholesterol. Inferences could not be made about the nutritional

treatment of total cholesterol, LDL-cholesterol and insulin resistance. Changes in lifestyle can promote an improvement in lipodystrophy and blood pressure. Regards, VergelDirectorhttp://powerusa.org/ http://www.testosteronewisdom.com/ http://www.agingwithhiv.org/ Groups:/ https://www.facebook.com/groups/testosteronereplacement/ https://www.facebook.com/PoWeRUSA?ref=ts

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