A novel chelation agent: MERCURY, LEAD, CADMIUM...?

[Guest guest]

Just came across this, sounds very interesting (sorry if it is old news:)

http://www.lef.org/magazine/mag2004/mar2004_report_citrus_01.htm

(go to page 2)

Has anyone used this/the brand they mention?

Natasa

Phytother Res. 2006 Oct;20(10):859-64.

The effect of modified citrus pectin on urinary excretion of toxic elements.

Eliaz I et al Amitabha Medical Clinic and Healing Center, 7064 Corline Ct. Ste A, Sebastopol, CA 95472, USA. ieliaz@...

This study was undertaken to evaluate the effect of

modified citrus pectin (MCP) on the urinary excretion of toxic elements

in healthy individuals. MCP is a reduced molecular weight pectin

(weight-average molar mass = 15,400) that is mostly linear

homogalacturonan with a 3.8% degree of esterification and approximately

10% rhamnogalacturonan II based on the presence of

2-keto-3-deoxy-octonic acid. Subjects ingested 15 g of MCP (PectaSol,

EcoNugenics Inc., Santa , California 95407) each day for 5 days and

20 g on day 6. Twenty-four hour urine samples were collected on day 1

and day 6 for comparison with baseline. The urine samples were analysed

for toxic and essential elements. In the first 24 h of MCP

administration the urinary excretion of arsenic increased significantly

(130%, p < 0.05). On day 6, urinary excretion was increased

significantly for cadmium (150%, p < 0.05). In addition, lead showed

a dramatic increase in excretion (560%, p < 0.08). This pilot trial

provides the first evidence that oral administration of MCP increases

significantly the urinary excretion of toxic metals in subjects with a

'normal' body load of metals. It is suggested that systemic chelation

of toxic metals by MCP may in part be attributable to the presence of

rhamnogalacturonan II, which has been shown previously to chelate

metals. Copyright 2006 Wiley & Sons, Ltd.

PMID: 16835878 [PubMed - in process]