A sudden spike in TSH and LDL

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I am treating a 70 year old woman for suspicious looking precancerous cell in her bladder and high urine lead levels. After several months, her lead levels returned to normal and examinations of her bladder revealed no abnormal cells. But now her TSH skyrocketed from 2.5 to 4.7 and her LDL rose from 135 to 247. Her Cholesterol/ HDL ratio is 7.6. She has been on 1.0 grain of Armour thyroid for about a year. I have been monitoring her labs regularly. This spike in values was unexpected and sudden. She also has tachycardia which she has had her whole life (and HTN). She is taking Niasafe, Gugul-lipid, trace minerals, zinc, UNDA 8, 33, 203 (on these her tachycardia dropped from 100 bpm to 80 bpm), magnesium taurate and fish oil. Any ideas on why the TSH and LDL jumped so high? , ND Klamath Falls, Or

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