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Glutathione and cold sores

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I've been getting weekly glutathione (i.v.'s) for several

weeks. My Naturopath calls them baby doses but I'm highly

reactive so they may not be baby doses for me.

I've also been getting a lot of cold sores since I started

the i.v.'s. I don't tolerate L-lysine, so I take a lot of

Valtrex to keep the cold sores from multiplying. I've had

cold sores since I was a child, decades before CFS came into

the picture.

These are the toughest most resistant cold sores I've ever

had. The Valtrex subdues them, then two days later they're

back. The Valtrex is becoming less effective.

Any ideas? Rich, any ideas from my 24 hour Urine Amino

Acids test? Rich posted his report on that test several

weeks ago.

Thanks to anyone who can help.

Kathy F.

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Kathy,

Have you done an IGG test for HSV1/HSV2 to see which one you have ?

Most cold sores are caused by HSV1 but I've heard that those caused by

HSV2 are quite a bit more aggressive.

Best wishes...

>

> I've been getting weekly glutathione (i.v.'s) for several

> weeks. My Naturopath calls them baby doses but I'm highly

> reactive so they may not be baby doses for me.

>

> I've also been getting a lot of cold sores since I started

> the i.v.'s. I don't tolerate L-lysine, so I take a lot of

> Valtrex to keep the cold sores from multiplying. I've had

> cold sores since I was a child, decades before CFS came into

> the picture.

>

> These are the toughest most resistant cold sores I've ever

> had. The Valtrex subdues them, then two days later they're

> back. The Valtrex is becoming less effective.

>

> Any ideas? Rich, any ideas from my 24 hour Urine Amino

> Acids test? Rich posted his report on that test several

> weeks ago.

>

> Thanks to anyone who can help.

>

> Kathy F.

>

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Thanks, Robin. Would the treatment be different for the

HSV2 cold sores? Will try to do some googling; I don't want

to fight for a test if the treatment is the same.

I didn't know there were two kinds of cold sores.

----- Original Message -----

From: " robin_tani " <robin_tani@...>

Have you done an IGG test for HSV1/HSV2 to see which one you

have ?

Most cold sores are caused by HSV1 but I've heard that those

caused by

HSV2 are quite a bit more aggressive.

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It's me again, Robin. Yikes, what a confusion of ideas.

One site does not agree with another. HSV2 seems more

likely to occur in the genital area but is more contagious.

Hope I read that correctly.

In what way could my glutathione i.v.'s trigger the cold

sores? Detox? Stressing an already stressed body, ie

unknown infections, challenged immune system, etc.

I don't have genital herpes. I've often thought that I was

amazingly lucky since I've had incredible outbreaks since

childhood, on my lips, in my nostrils and once in my eye,

(though that was disputed by a second opthamologist later

after the event).

I have been married for more than 40 years (same man), have

3 grown married children, and four grandchildren. None of

them have problems with cold sores. My husband occasionally

gets a small one on his lip and he thinks he's suffering big

time.

But he gets them very rarely. I must have the less

contagious kind, HSV1 since I've had these outbreaks since

I was a child. Some sites state HSV1 is more common to

the lips, HSV2 more common to the genital area.

I have not come across any useful information about the

difference in regards to treatment. Maybe more researching

later and perhaps a discussion in the Immune list.

Maybe there is no correlation to the glutathione. The

increase in outbreaks has increased since I started the

i.v.'s, but that does not mean there's a direct correlation.

Is there an advantage to having the IGG test? Sorry for

dumping on you but

you are the only one who has responded so far and you seem

knowledgeable..

Kathy F.

----- Original Message -----

From: " robin_tani " <robin_tani@...>

Kathy,

Have you done an IGG test for HSV1/HSV2 to see which one you

have ?

Most cold sores are caused by HSV1 but I've heard that those

caused by

HSV2 are quite a bit more aggressive.

Best wishes...

>

> I've been getting weekly glutathione (i.v.'s) for several

> weeks. My Naturopath calls them baby doses but I'm highly

> reactive so they may not be baby doses for me.

>

> I've also been getting a lot of cold sores since I started

> the i.v.'s. I don't tolerate L-lysine, so I take a lot of

> Valtrex to keep the cold sores from multiplying. I've had

> cold sores since I was a child, decades before CFS came

> into

> the picture.

>

> These are the toughest most resistant cold sores I've ever

> had. The Valtrex subdues them, then two days later

> they're

> back. The Valtrex is becoming less effective.

>

> Any ideas? Rich, any ideas from my 24 hour Urine Amino

> Acids test? Rich posted his report on that test several

> weeks ago.

>

> Thanks to anyone who can help.

>

> Kathy F.

>

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Hi, Kathy.

I'm sorry that the cold sores continue to plague you.

You may have said this before, and if so, I'm sorry to ask again,

but what happens when you take L-lysine? I'm asking because it may

have a bearing on your genetic variations.

Given that you don't tolerate lysine, I wonder if you can get

transdermal glutathione where you live. If you could use some of

that around your mouth, maybe it would raise the glutathione level

in the nerve cells where HSV-1 hangs out, that it could shut it

down. The work by Palamara et al. at the University of Rome says

glutathione will do this, if the concentration is high enough.

There are two makers of transdermal glutathione products that I know

of. One is http://www.leesilsby.com and the other is

http://www.kirkmangroup.com.

In regard to your urine amino acids test, I haven't had a chance to

study your responses to my comments on it yet. Life has been hectic.

Rich

>

> I've been getting weekly glutathione (i.v.'s) for several

> weeks. My Naturopath calls them baby doses but I'm highly

> reactive so they may not be baby doses for me.

>

> I've also been getting a lot of cold sores since I started

> the i.v.'s. I don't tolerate L-lysine, so I take a lot of

> Valtrex to keep the cold sores from multiplying. I've had

> cold sores since I was a child, decades before CFS came into

> the picture.

>

> These are the toughest most resistant cold sores I've ever

> had. The Valtrex subdues them, then two days later they're

> back. The Valtrex is becoming less effective.

>

> Any ideas? Rich, any ideas from my 24 hour Urine Amino

> Acids test? Rich posted his report on that test several

> weeks ago.

>

> Thanks to anyone who can help.

>

> Kathy F.

>

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I wrote out my reactions to L-lysine immediately - have

learned from experience how easy it is to forget what did

what. I was determined to stay on the 500 mg. for one week.

I also had an i.v. glutathione (10cc) mid-week. Throughout

the entire week the glands above my collar bone and below my

ears were painful and swollen. Other glands in my throat

were painful too, but not as severely.

I couldn't bear any light breeze blowing on my glands and

tended to keep them covered even though the air was warm. I

was extremely fatigued and continued to get more fatigued as

the week progressed.

I had pain in the joints of my fingers and in the tendons?

in my neck. This pain went away after I stopped the

L-lysine.

The first day with no L-lysine, my fatigue lessened

considerably and I was able to go out that evening to see my

grandchildren. I found it hard to believe that one day

could make such a difference. The day after I stopped the

lysine, I could feel the cold sores starting up deep in my

nostrils. Again, this seemed unbelievable. I resorted to

Valtrex which is always effective.

I am trying to find a supplier of 100 mg. L-lysine to see

whether I'll tolerate a lower dose. I've also heard of

'lipstick' moisturizer which contains lysine for times when

my lips are dry (a lot of wind and sun out here though I'm

not often outside).

I will research the sites on transdermal glutathione - it

will be more difficult to get this deep into my nostrils

where I often get cold sores. Lately, I've had more on my

lips.

Somewhere I read that you cannot get cold sores unless your

glutathione is low. Is this so? I have had numerous

outbreaks since I started the i.v.'s. I am waiting for the

results of my RBC glutathione test - should be here in a

couple of weeks.

I have one more i.v. glutathione appointment left. I got a

magnesium shot last week - magnesium showed low on my 24

hour Amino Acids test.

Since I don't tolerate any sulfur, I suspect blockage in my

methylation system, as written in your report. I have your

recommendations on that, ie Molybdenum (have tried this

before and gave it up but will need to search my notes for

the reasons) and P5P but have yet to start either of these.

I have serious digestions problems (acidic) and have a

closet full of supplements which I've tried and given up. B

vitamins are usually problematic.

I take Losec (Omeprazole) regularly - I stop periodically

but end up starting again. I am currently doing saliva ph

testing while on Losec and my ph has consistently been 6.0.

For awhile, the i.v'.s gave me a more energy, but that

hasn't lasted. I had to take a two week break because of

bronchitis. I suspect I need to take glutathione for a

longer period of time and use a method that is less

exhausting. They are expensive and I am not sure whether

there's any point in continuuing them. We discussed using a

nebulizer but after reading posts on the Experimental list,

I am beginning to wonder whether or not my body is capable

of building up glutathione in it's present condition.

I have tried the Epsom salt baths, but they seemed to tire

me out. I wonder if that is because the salt is a sulfate.

A quick search of the Kirkman Group site came up with:

Kirkman's Reduced L-Glutathione Lotion. Is this the right

product?

I know your life is crazed right now, Rich; I hate bothering

you. Thank you for responding.

Kathy F.

----- Original Message -----

Hi, Kathy.

I'm sorry that the cold sores continue to plague you.

You may have said this before, and if so, I'm sorry to ask

again,

but what happens when you take L-lysine? I'm asking because

it may

have a bearing on your genetic variations.

Given that you don't tolerate lysine, I wonder if you can

get

transdermal glutathione where you live. If you could use

some of

that around your mouth, maybe it would raise the glutathione

level

in the nerve cells where HSV-1 hangs out, that it could shut

it

down. The work by Palamara et al. at the University of Rome

says

glutathione will do this, if the concentration is high

enough.

There are two makers of transdermal glutathione products

that I know

of. One is http://www.leesilsby.com and the other is

http://www.kirkmangroup.com.

In regard to your urine amino acids test, I haven't had a

chance to

study your responses to my comments on it yet. Life has

been hectic.

Rich

>

> I've been getting weekly glutathione (i.v.'s) for several

> weeks. My Naturopath calls them baby doses but I'm highly

> reactive so they may not be baby doses for me.

>

> I've also been getting a lot of cold sores since I started

> the i.v.'s. I don't tolerate L-lysine, so I take a lot of

> Valtrex to keep the cold sores from multiplying. I've had

> cold sores since I was a child, decades before CFS came

> into

> the picture.

>

> These are the toughest most resistant cold sores I've ever

> had. The Valtrex subdues them, then two days later

> they're

> back. The Valtrex is becoming less effective.

>

> Any ideas? Rich, any ideas from my 24 hour Urine Amino

> Acids test? Rich posted his report on that test several

> weeks ago.

>

> Thanks to anyone who can help.

>

> Kathy F.

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====It is my understanding that when there is an imbalance between

l-Arginine and l-Lysine with l-Arginine too high, that that allows the virus to

reassert itself. And, that is why for most people l-Lysine is effective in

suppressing the viruses, it restores the balance.

Somewhere I read that you cannot get cold sores unless your

glutathione is low. Is this so? I have had numerous

outbreaks since I started the i.v.'s. I am waiting for the

results of my RBC glutathione test - should be here in a

couple of weeks.

=====Tired out or relaxed enough to sleep, etc. THat's what Mg SO4 is

supposed to do.

I have tried the Epsom salt baths, but they seemed to tire

me out. I wonder if that is because the salt is a sulfate.

I know your life is crazed right now, Rich; I hate bothering

you. Thank you for responding.

Kathy F.

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

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See Dr Baschetti's work with Licorice root and CFIDS and viruses. Italy.

In a message dated 5/16/2006 2:11:21 PM Eastern Daylight Time,

writes:

I had also

corresponded with HHV-6 foundation and they confirmed in-vitro (petri

dish) inhibition power of licorice on HHV-6, all the more evidence

that licorice really has potent effects on the Herpes family of viruses.

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

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Hi Kathy,

Quite frankly no, the treatment would be the same. In everything I've

read, the vulnerabilities of HSV 1 & 2 seem to be identical.

You said that you can't tolerate L-Lysine. Why? Do you get digestion

problems ? Lysine is probably the best easily obtained suppressor of

herpes that I know of. But if you're really having a big issue with

recurrent cold sores perhaps it's worth considering the following.

It's been recently known that HHV-8 seems highly susceptible to

Licorice root. Digesting it doesn't really help that much since blood

absorbtion is minimal. In the reports that I've read, a licorice

based compound had been injected directly into the infected tissue of

Kaposi Sarcoma (a type of cancer almost exclusive caused by HHV-8).

Amazingly, in some cases, latent infection was eradicated!!! That's a

first for any herpes virus since they're usually very well tuned for

established latent infection in a wide range of cells.

I have a strong premonition that doing a similar procedure into the

HSV infected lip tissue might have some positive effects. I had also

corresponded with HHV-6 foundation and they confirmed in-vitro (petri

dish) inhibition power of licorice on HHV-6, all the more evidence

that licorice really has potent effects on the Herpes family of viruses.

Lastly, have you tested your IGG [subclass] levels ? People with low

levels IGG subclass 1 and 3 seem to be particularly prone to getting

horrible cold sores along with other viral infections.

Best wishes.

>

> Thanks, Robin. Would the treatment be different for the

> HSV2 cold sores? Will try to do some googling; I don't want

> to fight for a test if the treatment is the same.

>

> I didn't know there were two kinds of cold sores.

>

> ----- Original Message -----

> From: " robin_tani " <robin_tani@...>

>

> Have you done an IGG test for HSV1/HSV2 to see which one you

> have ?

> Most cold sores are caused by HSV1 but I've heard that those

> caused by

> HSV2 are quite a bit more aggressive.

>

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