Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 I've been getting weekly glutathione (i.v.'s) for several weeks. My Naturopath calls them baby doses but I'm highly reactive so they may not be baby doses for me. I've also been getting a lot of cold sores since I started the i.v.'s. I don't tolerate L-lysine, so I take a lot of Valtrex to keep the cold sores from multiplying. I've had cold sores since I was a child, decades before CFS came into the picture. These are the toughest most resistant cold sores I've ever had. The Valtrex subdues them, then two days later they're back. The Valtrex is becoming less effective. Any ideas? Rich, any ideas from my 24 hour Urine Amino Acids test? Rich posted his report on that test several weeks ago. Thanks to anyone who can help. Kathy F. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 Kathy, Have you done an IGG test for HSV1/HSV2 to see which one you have ? Most cold sores are caused by HSV1 but I've heard that those caused by HSV2 are quite a bit more aggressive. Best wishes... > > I've been getting weekly glutathione (i.v.'s) for several > weeks. My Naturopath calls them baby doses but I'm highly > reactive so they may not be baby doses for me. > > I've also been getting a lot of cold sores since I started > the i.v.'s. I don't tolerate L-lysine, so I take a lot of > Valtrex to keep the cold sores from multiplying. I've had > cold sores since I was a child, decades before CFS came into > the picture. > > These are the toughest most resistant cold sores I've ever > had. The Valtrex subdues them, then two days later they're > back. The Valtrex is becoming less effective. > > Any ideas? Rich, any ideas from my 24 hour Urine Amino > Acids test? Rich posted his report on that test several > weeks ago. > > Thanks to anyone who can help. > > Kathy F. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 Thanks, Robin. Would the treatment be different for the HSV2 cold sores? Will try to do some googling; I don't want to fight for a test if the treatment is the same. I didn't know there were two kinds of cold sores. ----- Original Message ----- From: " robin_tani " <robin_tani@...> Have you done an IGG test for HSV1/HSV2 to see which one you have ? Most cold sores are caused by HSV1 but I've heard that those caused by HSV2 are quite a bit more aggressive. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 It's me again, Robin. Yikes, what a confusion of ideas. One site does not agree with another. HSV2 seems more likely to occur in the genital area but is more contagious. Hope I read that correctly. In what way could my glutathione i.v.'s trigger the cold sores? Detox? Stressing an already stressed body, ie unknown infections, challenged immune system, etc. I don't have genital herpes. I've often thought that I was amazingly lucky since I've had incredible outbreaks since childhood, on my lips, in my nostrils and once in my eye, (though that was disputed by a second opthamologist later after the event). I have been married for more than 40 years (same man), have 3 grown married children, and four grandchildren. None of them have problems with cold sores. My husband occasionally gets a small one on his lip and he thinks he's suffering big time. But he gets them very rarely. I must have the less contagious kind, HSV1 since I've had these outbreaks since I was a child. Some sites state HSV1 is more common to the lips, HSV2 more common to the genital area. I have not come across any useful information about the difference in regards to treatment. Maybe more researching later and perhaps a discussion in the Immune list. Maybe there is no correlation to the glutathione. The increase in outbreaks has increased since I started the i.v.'s, but that does not mean there's a direct correlation. Is there an advantage to having the IGG test? Sorry for dumping on you but you are the only one who has responded so far and you seem knowledgeable.. Kathy F. ----- Original Message ----- From: " robin_tani " <robin_tani@...> Kathy, Have you done an IGG test for HSV1/HSV2 to see which one you have ? Most cold sores are caused by HSV1 but I've heard that those caused by HSV2 are quite a bit more aggressive. Best wishes... > > I've been getting weekly glutathione (i.v.'s) for several > weeks. My Naturopath calls them baby doses but I'm highly > reactive so they may not be baby doses for me. > > I've also been getting a lot of cold sores since I started > the i.v.'s. I don't tolerate L-lysine, so I take a lot of > Valtrex to keep the cold sores from multiplying. I've had > cold sores since I was a child, decades before CFS came > into > the picture. > > These are the toughest most resistant cold sores I've ever > had. The Valtrex subdues them, then two days later > they're > back. The Valtrex is becoming less effective. > > Any ideas? Rich, any ideas from my 24 hour Urine Amino > Acids test? Rich posted his report on that test several > weeks ago. > > Thanks to anyone who can help. > > Kathy F. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 Hi, Kathy. I'm sorry that the cold sores continue to plague you. You may have said this before, and if so, I'm sorry to ask again, but what happens when you take L-lysine? I'm asking because it may have a bearing on your genetic variations. Given that you don't tolerate lysine, I wonder if you can get transdermal glutathione where you live. If you could use some of that around your mouth, maybe it would raise the glutathione level in the nerve cells where HSV-1 hangs out, that it could shut it down. The work by Palamara et al. at the University of Rome says glutathione will do this, if the concentration is high enough. There are two makers of transdermal glutathione products that I know of. One is http://www.leesilsby.com and the other is http://www.kirkmangroup.com. In regard to your urine amino acids test, I haven't had a chance to study your responses to my comments on it yet. Life has been hectic. Rich > > I've been getting weekly glutathione (i.v.'s) for several > weeks. My Naturopath calls them baby doses but I'm highly > reactive so they may not be baby doses for me. > > I've also been getting a lot of cold sores since I started > the i.v.'s. I don't tolerate L-lysine, so I take a lot of > Valtrex to keep the cold sores from multiplying. I've had > cold sores since I was a child, decades before CFS came into > the picture. > > These are the toughest most resistant cold sores I've ever > had. The Valtrex subdues them, then two days later they're > back. The Valtrex is becoming less effective. > > Any ideas? Rich, any ideas from my 24 hour Urine Amino > Acids test? Rich posted his report on that test several > weeks ago. > > Thanks to anyone who can help. > > Kathy F. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 15, 2006 Report Share Posted May 15, 2006 I wrote out my reactions to L-lysine immediately - have learned from experience how easy it is to forget what did what. I was determined to stay on the 500 mg. for one week. I also had an i.v. glutathione (10cc) mid-week. Throughout the entire week the glands above my collar bone and below my ears were painful and swollen. Other glands in my throat were painful too, but not as severely. I couldn't bear any light breeze blowing on my glands and tended to keep them covered even though the air was warm. I was extremely fatigued and continued to get more fatigued as the week progressed. I had pain in the joints of my fingers and in the tendons? in my neck. This pain went away after I stopped the L-lysine. The first day with no L-lysine, my fatigue lessened considerably and I was able to go out that evening to see my grandchildren. I found it hard to believe that one day could make such a difference. The day after I stopped the lysine, I could feel the cold sores starting up deep in my nostrils. Again, this seemed unbelievable. I resorted to Valtrex which is always effective. I am trying to find a supplier of 100 mg. L-lysine to see whether I'll tolerate a lower dose. I've also heard of 'lipstick' moisturizer which contains lysine for times when my lips are dry (a lot of wind and sun out here though I'm not often outside). I will research the sites on transdermal glutathione - it will be more difficult to get this deep into my nostrils where I often get cold sores. Lately, I've had more on my lips. Somewhere I read that you cannot get cold sores unless your glutathione is low. Is this so? I have had numerous outbreaks since I started the i.v.'s. I am waiting for the results of my RBC glutathione test - should be here in a couple of weeks. I have one more i.v. glutathione appointment left. I got a magnesium shot last week - magnesium showed low on my 24 hour Amino Acids test. Since I don't tolerate any sulfur, I suspect blockage in my methylation system, as written in your report. I have your recommendations on that, ie Molybdenum (have tried this before and gave it up but will need to search my notes for the reasons) and P5P but have yet to start either of these. I have serious digestions problems (acidic) and have a closet full of supplements which I've tried and given up. B vitamins are usually problematic. I take Losec (Omeprazole) regularly - I stop periodically but end up starting again. I am currently doing saliva ph testing while on Losec and my ph has consistently been 6.0. For awhile, the i.v'.s gave me a more energy, but that hasn't lasted. I had to take a two week break because of bronchitis. I suspect I need to take glutathione for a longer period of time and use a method that is less exhausting. They are expensive and I am not sure whether there's any point in continuuing them. We discussed using a nebulizer but after reading posts on the Experimental list, I am beginning to wonder whether or not my body is capable of building up glutathione in it's present condition. I have tried the Epsom salt baths, but they seemed to tire me out. I wonder if that is because the salt is a sulfate. A quick search of the Kirkman Group site came up with: Kirkman's Reduced L-Glutathione Lotion. Is this the right product? I know your life is crazed right now, Rich; I hate bothering you. Thank you for responding. Kathy F. ----- Original Message ----- Hi, Kathy. I'm sorry that the cold sores continue to plague you. You may have said this before, and if so, I'm sorry to ask again, but what happens when you take L-lysine? I'm asking because it may have a bearing on your genetic variations. Given that you don't tolerate lysine, I wonder if you can get transdermal glutathione where you live. If you could use some of that around your mouth, maybe it would raise the glutathione level in the nerve cells where HSV-1 hangs out, that it could shut it down. The work by Palamara et al. at the University of Rome says glutathione will do this, if the concentration is high enough. There are two makers of transdermal glutathione products that I know of. One is http://www.leesilsby.com and the other is http://www.kirkmangroup.com. In regard to your urine amino acids test, I haven't had a chance to study your responses to my comments on it yet. Life has been hectic. Rich > > I've been getting weekly glutathione (i.v.'s) for several > weeks. My Naturopath calls them baby doses but I'm highly > reactive so they may not be baby doses for me. > > I've also been getting a lot of cold sores since I started > the i.v.'s. I don't tolerate L-lysine, so I take a lot of > Valtrex to keep the cold sores from multiplying. I've had > cold sores since I was a child, decades before CFS came > into > the picture. > > These are the toughest most resistant cold sores I've ever > had. The Valtrex subdues them, then two days later > they're > back. The Valtrex is becoming less effective. > > Any ideas? Rich, any ideas from my 24 hour Urine Amino > Acids test? Rich posted his report on that test several > weeks ago. > > Thanks to anyone who can help. > > Kathy F. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2006 Report Share Posted May 16, 2006 ====It is my understanding that when there is an imbalance between l-Arginine and l-Lysine with l-Arginine too high, that that allows the virus to reassert itself. And, that is why for most people l-Lysine is effective in suppressing the viruses, it restores the balance. Somewhere I read that you cannot get cold sores unless your glutathione is low. Is this so? I have had numerous outbreaks since I started the i.v.'s. I am waiting for the results of my RBC glutathione test - should be here in a couple of weeks. =====Tired out or relaxed enough to sleep, etc. THat's what Mg SO4 is supposed to do. I have tried the Epsom salt baths, but they seemed to tire me out. I wonder if that is because the salt is a sulfate. I know your life is crazed right now, Rich; I hate bothering you. Thank you for responding. Kathy F. mjh " The Basil Book " http://foxhillfarm.us/FireBasil/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2006 Report Share Posted May 16, 2006 See Dr Baschetti's work with Licorice root and CFIDS and viruses. Italy. In a message dated 5/16/2006 2:11:21 PM Eastern Daylight Time, writes: I had also corresponded with HHV-6 foundation and they confirmed in-vitro (petri dish) inhibition power of licorice on HHV-6, all the more evidence that licorice really has potent effects on the Herpes family of viruses. mjh " The Basil Book " http://foxhillfarm.us/FireBasil/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 16, 2006 Report Share Posted May 16, 2006 Hi Kathy, Quite frankly no, the treatment would be the same. In everything I've read, the vulnerabilities of HSV 1 & 2 seem to be identical. You said that you can't tolerate L-Lysine. Why? Do you get digestion problems ? Lysine is probably the best easily obtained suppressor of herpes that I know of. But if you're really having a big issue with recurrent cold sores perhaps it's worth considering the following. It's been recently known that HHV-8 seems highly susceptible to Licorice root. Digesting it doesn't really help that much since blood absorbtion is minimal. In the reports that I've read, a licorice based compound had been injected directly into the infected tissue of Kaposi Sarcoma (a type of cancer almost exclusive caused by HHV-8). Amazingly, in some cases, latent infection was eradicated!!! That's a first for any herpes virus since they're usually very well tuned for established latent infection in a wide range of cells. I have a strong premonition that doing a similar procedure into the HSV infected lip tissue might have some positive effects. I had also corresponded with HHV-6 foundation and they confirmed in-vitro (petri dish) inhibition power of licorice on HHV-6, all the more evidence that licorice really has potent effects on the Herpes family of viruses. Lastly, have you tested your IGG [subclass] levels ? People with low levels IGG subclass 1 and 3 seem to be particularly prone to getting horrible cold sores along with other viral infections. Best wishes. > > Thanks, Robin. Would the treatment be different for the > HSV2 cold sores? Will try to do some googling; I don't want > to fight for a test if the treatment is the same. > > I didn't know there were two kinds of cold sores. > > ----- Original Message ----- > From: " robin_tani " <robin_tani@...> > > Have you done an IGG test for HSV1/HSV2 to see which one you > have ? > Most cold sores are caused by HSV1 but I've heard that those > caused by > HSV2 are quite a bit more aggressive. > Quote Link to comment Share on other sites More sharing options...
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