FW: Diabetes - Hepatitis - Pituitary

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Diabetes - Hepatitis - Pituitary

Diabetes + Hepatitis

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1966 - " Free " and " bound " insulin activity in the

blood of patients with

acute epidemic hepatitis. PMID: 5225081

1975 - Hepatitis B (Australia) antigen in

diabetics. PMID: 1138253

1981 - Detection of HBsAg in the pancreas.PMID:

7025575

1994 - IFN - Occurrence of IDDM [insulin-dependent

diabetes mellitus] during

interferon therapy for chronic viral hepatitis.

During and after IFN therapy

we should consider the possibility of occurrence

of IDDM as well as other

autoimmune diseases and observe the clinical

course carefully. PMID: 8013261

1998 - Association of chronic hepatitis C

infection and diabetes mellitus.

Pancreatic beta -cells might be an extrahepatic

target of HCV. PMID:

10228436

1998 - HCV infection and diabetes mellitus:

influence of the use of finger

stick devices on nosocomial transmission. An

increased prevalence of (HCV)

infection in patients with diabetes mellitus has

suggested a link between

these two conditions and the possibility of

patient-to-patient HCV

transmission during hospital admissions in

diabetes units. Our findings

indicate that these medical practices play no role

in nosocomial

transmission of HCV in diabetic patients. UI:

20099692

1999 - HAV - Hepatitis A-induced diabetes

mellitus, acute renal failure, and

liver failure. This case illustrates that

hepatitis A infection may be

severe with liver failure, acute renal failure,

and permanent diabetes

mellitus as sequale of this infection. UI:

99300059

1999 - Association of diabetes mellitus and

chronic hepatitis C virus

infection. While patients with liver disease are

known to have a higher

prevalence of glucose intolerance, preliminary

studies suggest that (HCV)

infection may be an additional risk factor for the

development of diabetes

mellitus. In the former study diabetes was

observed in 21% of HCV-infected

patients compared with 12% of HBV-infected

subjects. Data suggest a

relatively strong association between HCV

infection and diabetes, because

diabetics have an increased frequency of HCV

infection, particularly with

genotype 2a. Furthermore, it is possible that HCV

infection may serve as an

additional risk factor for the development of

diabetes, beyond that

attributable to chronic liver disease alone. PMID:

9918906

1999 - Non-insulin-dependent diabetes mellitus

[NIDDM]. Confirms an

association between HCV and NIDDM. PMID: 10498660

1999 - Extrahepatic clinical manifestations are

frequently observed in HCV

patients and involve primarily the joints,

muscles, and skin. The most

frequent immunologic abnormalities include mixed

cryoglobulins, antinuclear

antibodies, and anti-smooth muscle antibodies.

99452326

1999 - Absence of evidence of a possible

connection vaccination for

hepatitis B and the development of diabetes type

1. UI: 20060455

1999 - Type I membranoproliferative

glomerulonephritis (MPGN). Clinicians

should be aware of the possible occurrence of Type

I MPGN and

cryoglobulinemia in patients with diabetes

mellitus and HCV infection with

the appropriate history and physical findings. UI:

99140646

1999 - This case supports the hypothesis that

IFN-alpha therapy may lead to

an augmented autoimmune reaction against islet

cell antigens resulting in

the development of diabetes mellitus type 1,

especially if there are other

predisposing factors before IFN treatment. UI:

99251104

1999 - Reversible impact of alpha-interferon on

carbohydrate (CH) metabolism

was observed in patients with hepatitis C treated

with interferon between

1993 and 1997. UI: 99372081

1999 - Interferon-alpha improves glucose tolerance

in diabetic and

non-diabetic patients with HCV-induced liver

disease. This pilot study was

initiated to evaluate factors controlling glucose

tolerance in patients with

hepatitis C virus-induced liver disease before and

after therapy with

recombinant interferon-alpha (r-INF-alpha).

Therapy with recombinant

interferon-alpha is associated with an

amelioration of glucose tolerance in

non-diabetic and diabetic HCV-infected patients.

UI: 20008755

1999 - Hepatic iron overload has been reported in

various metabolic

conditions, including the insulin-resistance

syndrome (IRS) and nonalcoholic

steatohepatitis (NASH). The aim of this study was

to show that such hepatic

iron overload is part of a unique and unrecognized

entity. UI: 20005917

1999 - High prevalence of diabetes mellitus among

adult beta-thalassaemic

patients - Patients with thalassaemia and HCV

infection were diabetic more

often than thalassaemic patients without HCV

infection (45.3% versus 11.3%.

It is probable that the coexistence of

haemochromatosis makes the effect of

HCV infection on glucose metabolism clinically

evident, even in the stage of

chronic hepatitis. 99431167

1999 - Fatal liver failure after corticosteroid

treatment of a hepatitis B

virus carrier. a known carrier of (HBV) after

blood transfusion, developed

increasingly severe jaundice with high

transaminase levels after receiving

steroids in high doses. Significant preceding

conditions included chronic

obstructive pulmonary disease, coronary heart

disease, ulcerative colitis in

remission and diabetes mellitus. Steroids should

be given to known hepatitis

B carriers only if strictly indicated, because of

the danger of acute

deterioration of liver functions by reactivation

of the disease with

possibly fatal consequences. If steroids are

administered, liver functions

and serological hepatitis markers should be

closely monitored so that any

necessary treatment can be quickly initiated. UI:

99322652

2000 - HCV - Diabetes Mellitus. PMID: 10707860

2000 - Correlated with HCV infection; diabetes

mellitus. PMID: 10647955

2000 - An increasing prevalence of hepatitis C and

B, often associated, in

type 2 diabetic patients that allows us to define

them as a group at risk

for viral hepatitis. PMID: 10802152

2000 - HCV - Viral replication in pancreas. PMID:

10712785

2000 - High prevalence and adverse effect of

hepatitis C virus infection in

type II diabetic-related nephropathy. PMID:

10752528

2000 - Patients with chronic HCV infection have an

increased prevalence of

type 2 diabetes, and this prevalence is

independent of cirrhosis. PMID:

10761489

2000 - There is a high prevalence of diabetes

among liver transplant

recipients infected with HCV both before and after

[liver] transplantation.

PMID: 10869293

2000 - Impact of HCV infection on development of

posttransplantation

diabetes mellitus in renal allograft recipients.

PMID: 10812113

Pituitary

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1965 - Trial of adrenal function tests viral

hepatitis. PMID: 5883559

1969 - The state of the pituitary-adrenal system

in patients with acute

protracted and chronic epidemic hepatitis. PMID:

5371494

1971 - Pituitary-corticoadrenal secretory tonus in

chronic hepatitis. PMID:

5565775

1994 - HBV - The DNA sequence representing HBV

infection was detected in the

tissue of liver (100%), gallbladder (85.7%),

spleen (75.0%), kidney (72.7%)

adrenal gland (66.7%), heart (55.6%), testicle

(55.6%), pancreas (54.5%)

respectively. PMID: 7956560

1996 - HCV - Prolactin-secreting pituitary

microadenoma. PMID: 8766348

1996 - Case of C-type chronic hepatitis with

manifestation of pituitary

insufficiency caused by interferon therapy. PMID:

8999070

1996 - Levels of pituitary-thyroid axis hormones

in men during the course of

chronic active hepatitis and liver cirrhosis. A

significant decline of TT3,

TT4, fT3, fT4 concentration and TT3/TT4 index in

males with liver cirrhosis

were observed. PMID: 9082343

1998 - Change of peripheral levels of pituitary

hormones and cytokines after

injection of interferon (IFN)-beta in patients

with chronic hepatitis C.

Plasma ACTH levels increased significantly. These

in vivo results are

important for investigating the relationship

between endocrine and cytokine

systems in humans. PMID: 9768684

1998 - Change of peripheral levels of pituitary

hormones and cytokines after

injection of interferon (IFN)-beta in patients

with chronic hepatitis C.

PMID: 9768684

1999 - Hepatic ischemia and hypophyseal

macroadenoma. Recurrent hepatitis

[no viral type mentioned] secondary to a pituitary

macroadenoma in a 55-year

old man. Liver ischemia is thought to be the main

consequence of episodes of

acute adrenal insufficiency. Sudden acute adrenal

insufficiency was due to

enlargement of the sella content secondary to

several microhemorrhages in

the macroadenoma. PMID: 10219616

1999 - Macrophage migration inhibitory factor

(MIF) - Pituitary-derived

hormone - (MIF) have been extensively

re-evaluated. This has been found to

be protein involved in broad-spectrum

pathophysiological states as an

glucocorticoid-induced immunomodulator. PMID:

10347118

Other

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Symptoms of Mercury Poisoning - Diabetes

Insipidus-like symptoms.

http://www.mercury-free.com/sympts.htm

Note:

1996 - Hepatitis B Immune globulin (HBIg) -

Potential for mercury toxicity

and HCV transmission in the HBIg formulations

currently available in the

United States. Manufacturing modifications of HBIg

may allow for improved

patient tolerance and decreased risks. PMID:

8996763

Background Note:

-------------------------

Diabetes - (Gr. Diabetes a syphon, from dia

through + bainein to go) a

general term referring to disorders characterised

by excessive urine

excretion (polyuria), as in diabetes mellitus and

diabetes insipidus. When

used alone, the term refers to diabetes mellitus.

http://www.graylab.ac.uk/cgi-bin/omd?query=Diabete

s

Diabetes Mellitus - Relative or absolute lack of

insulin leading to

uncontrolled carbohydrate metabolism. In juvenile

onset diabetes (that may

be an autoimmune response to pancreatic cells)

the insulin deficiency tends

to be almost total, whereas in adult onset

diabetes there seems to be no

immunological component but an association with

obesity.

http://www.graylab.ac.uk/cgi-bin/omd?diabetes+mell

itus

Diabetes Insipidus (DI) - Rare form of diabetes in

which the kidney tubules

do not reabsorb sufficient water. This can be

because (a) either the renal

tubules have defective receptors for antidiuretic

hormone (ADH, vasopressin)

or ( a class of aquaporin water channel in the

collecting duct is

defective or © there is inadequate ADH

production by the pituitary,

leading to the excessive production of dilute

urine.

http://www.graylab.ac.uk/cgi-bin/omd?diabetes+insi

pidus

There are four (4) fundamentally different types

of Diabetes Insipidus (DI).

Each has a different cause and must be treated in

a different way. These

four forms are:

Neurogenic, also known as central, hypothalamic,

pituitary or

neurohypophyseal is caused by a deficiency of the

antidiuretic hormone,

vasopressin.

Nephrogenic, also known as vasopressin-resistant

is caused by insensitivity

of the kidneys to the effect of the antidiuretic

hormone, vasopressin.

Gestagenic, also known as gestational is also

caused by a deficiency of the

antidiuretic hormone, vasopressin, that occurs

only during pregnancy.

Dipsogenic, a form of primary polydipsia is caused

by abnormal thirst and

the excessive intake of water or other liquids.

http://diabetesinsipidus.maxinter.net/

To get the citation listed above enter 'only' the

PMID 'numbers' at:

http://www.ncbi.nlm.nih.gov/PubMed/