Health effect of bromopropane

[Guest Deepti]

Hello All ,

 

Bromopropane is a substance widely used in Industry . As per the following are the main things about  bromo propane-

 

What is 1-Bromopropane?
1-Bromopropane, also known as n-propyl bromide (nPB), is a solvent (CAS 106-94-5) with several commercial applications. Use of 1-BP has increased in workplaces over the past 20 years. 1-BP is often found in products used in:
• Vapor and immersion degreasing operations for cleaning metals, plastics and electronic and optical components;
• Adhesive spray applications;
• Dry cleaning; and
• Solvent sprays used in operations like asphalt production, aircraft maintenance, and synthetic fiber manufacturing.

 

Case Study

Six foam cushion gluers who were exposed to 1-BP vapors from spray adhesives were seen in a medical clinic for neurotoxicity. The workers had been employed at the facility from 3 months to 3 years. All patients complained of slow onset of lower extremity pain or numbness. Five of six complained of difficulty walking, and on examination had leg spasms, loss of sensation in limbs and muscle twitching. Three patients initially had nausea and headache. Serum bromide concentrations and air samples were obtained to assess exposure. A seven-hour time-weighted average air concentration of 1-BP was found to be 108 ppm (range 92–127 ppm). Two years after exposure, the two most severely affected patients still had trouble with walking and loss of feeling in their legs and they, along with a third patient, continued to feel pain most of the time.

 

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