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Article:Underlying causes of erythema nodosum

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Underlying causes of erythema nodosum In 60% of cases of erythema nodosum, no cause is found. Vascular

deposition of immunoglobulin complexes and complement has been

hypothesized as the cause of septal panniculitis, but evidence of this

pathophysiologic process remains elusive. Although the mechanism of

erythema nodosum is unknown, the list of clinical causes is growingNODOSUM: A mnemonic for causes of erythema nodosum

NOcause is found in 60% of cases

Drug (iodides, bromides, sulfonamides)

Oral contraceptives

Sarcoidosis or Löfgren's syndrome

Ulcerative colitis, Crohn's disease, Behçet's syndrome

Microbiology: any chronic infection (bacterial, viral, yersinia, tuberculosis, leprosy, deep fungal)

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In a message dated 11/26/2006 12:21:12 A.M. Pacific Standard Time, erythema_nodosum_Group writes:

NODOSUM: A mnemonic for causes of erythema nodosum NOcause is foundin 60% of cases Drug (iodides, bromides, sulfonamides) Oralcontraceptives Sarcoidosis or Löfgren's syndrome Ulcerative colitis,Crohn's disease, Behçet's syndrome Microbiology: any chronicinfection (bacterial, viral, yersinia, tuberculosis, leprosy, deepfungal)

, To your knowledge has anyone explored environmental sensitivities as a cause for EN. Seems to me that with such a high percentage having no known cause, that would be a place to look, especially for things in our surroundings that are considered pollutants.

lie

RA from 1997

EN in remission with treatment for RA

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Hi lie,

One member, Teri I think, thought she was getting EN from exposure to

toxic mold. I think many of us are super sensitive to many triggers,

environmental included, and that makes it hard to figure out exactly

what causes our EN outbreaks. The thing about environmental triggers

is how will you eliminate them even if you know it is the cause? From

what I've read, our environment is really polluted and it may take a

long time and a major money commitment to clean it up. Still, that is

no reason not to clean it up. I feel it has to be done, and the sooner

the better.

Love,

idio. EN

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