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Re: How to raise Secretory IgA

5 replies to this topic      (299 views)

#1 *guest

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Posted 24 June 2004 - 09:46 AM

Hi Suzanne,

> Does anyone know how to raise Secretory IGA? Mine is consistanly low, very
> low on my ASI tests and I think this is why I have so many bowel infections.
> Any ideas? What makes it go low in the first place? MIne is 5 and normal is
> something like 25-60....

I heard an endocrinologist say that there is now way to raise IgA. I assume
he would have included Secretory IgA, but he didn't say. He did serum IgA
testing.

He said that in people with Selective IgA Deficiency, a primary immune
deficiency disease, their B cells are supposed to make IgA, but they don't.
He said that this due either to an acquired or inherited defect in the B
cells.

Most doctors dismiss Selective IgA Deficiency as being trivial and say that
it is very rare. (as rare as 1 out of 17,000)

I don't have time to look for the link right now, but I was not surprised
when I read recently that 1 out of 5 children who were patients at an
infectious disease clinic had Selective IgA Deficiency. My personal opinion
is that this immune deficiency can play a large part in chronic illnesses.

I've heard several on this list say they have either low or no IgA. It's
easy to test for, and I'm surprised that everyone with CFIDS or Lyme isn't
tested. Even if nothing can be done about it, it's another piece of the
puzzle.

Sue ,
Upstate New York

#2 *guest

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Posted 23 June 2004 - 09:19 PM

On Wed, 23 Jun 2004, Suzanne Crossley wrote:

> Does anyone know how to raise Secretory IGA? Mine is consistanly low, very
low on my ASI tests and I think this is why I have so many bowel infections.
Any ideas? What makes it go low in the first place? MIne is 5 and normal is
something like 25-60....

I would not have a clue as I just had my IGA tested and it is almost twice
the upper limit of normal. High IGA levels can be linked to autoimmune
diseases but IGA deficiency is a worse problem than high.

margo

#3 *guest

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Posted 28 June 2004 - 08:02 AM


> Does anyone know how to raise Secretory IGA?

Vitamin A is worth trying. It raises nonspecific immunity because it
improves the integrity of the skin and the mucus membranes. Vitamin
A is critical to helping improve the " leaky gut. " It has the direct
ability to raise secretory IgA and it raises the lysozymes in tears
and in saliva. But it also functions in specific immunity.

Meditation and Vizualisation may be helpful:

Increased secretory immunoglobulin A (IgA) (significantly higher
than control group) following training in location, activity, and
morphology of IgA and 6 weeks of daily imaging.

Rider, M.S., J. Achterberg, G.F. Lawlis, A. Goven, R. Toledo, and
J.R. . 1990. Effect of immune system imagery on secretory IgA.


Good quality probiotics and colustrum (eg www.neovite.com) make a
very real difference.

Low IgA is frequently found in celiacs and those with chronic
candidiasis, two problems that are treatable. Taking good strong
probiotics is important with an IgA deficiency. Colustrum
(www.neovite.com) may be helpful also.

Selective deficiency of IgA is defined as low levels of or complete
absence of immune globulin A, which causes decreased immune function
in the mucosal surfaces (e.g., mouth, gastrointestinal tract, and
lungs) and results in increased risk for respiratory and
gastrointestinal infections.Affected people often have chronic
diarrhea caused by intestinal infections, frequent respiratory
infections. Many develop autoimmune diseases like rheumatoid
arthritis and lupus erythematosus.

Some people with IgA deficiency will recover spontaneously and begin
to produce IgA in larger quantities over a period of years.

#4 *guest

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Posted 28 June 2004 - 07:14 AM


> Does anyone know how to raise Secretory IGA?

Here's one way... Laughter

At Western New England College in Springfield, Massachusetts,
scientists tracked correlations between laughter and infection-
fighting antibodies found in saliva. This study involved 10
students, five of whom watched a humorous video while the remaining
five watched a lecture on anxiety. Researchers took saliva samples
from each of the subjects both before and after viewing. The
results showed that the antibody levels in those who watched the
lecture remained the same, while those who watched the funny video
showed a significant increase of Immunoglobulin A (IgA), the
antibody that combats upper respiratory infections ( 71).

In a similar experiment in the Schools of Medicine and Public Health
at Loma University in California, Lee S. Berk, studied how
activity in the immune system is affected by a positive reaction to
comical videos. By analyzing blood samples taken from the subjects
who watched the humorous videos Berk discovered that, in addition to
an increase in IgA, levels of cortisol, which suppresses the immune
system, drop significantly. The activity of natural killer cells,
which seek out and destroy abnormal cells, increase significantly
and levels of plasma cytokine gamma interferon, which enhances
immune-system functioning, more than double (Clay 18).

, Patti. She Who Laughs, Lasts! Redbook Jan. 1991: 70-73.
Clay, A. Researchers Harness the Power of Humor. APA Monitor
Sept. 1997,

#5 *guest

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Posted 28 June 2004 - 02:02 PM

Wow, , this is very interesting. Could give us some kind of
window on how these illnesses affect us neurologically.

I've experienced such a change in mood since reducing my
inflammation on the Marshall Protocol that I find myself laughing a
lot now. I never used to find things so consistently funny. It's
been a really surprising effect of this protocol. Generally elevated
mood and a much expanded sense of humor. Perhaps these illnesses
suppress every unnecessary mechanism, except those that specifically
exist to fight off pathogens? (Even our funny bone? lol!)

I know that if my immune system is fighting off some kind of flu or
virus, I definitely don't feel much like laughing and would probably
feel worse if I did. You know, it only hurts when I laugh. :-)

penny


> > > Does anyone know how to raise Secretory IGA?
> >
> > Here's one way... Laughter

#6 *guest

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Posted 26 July 2004 - 06:50 PM

Hi, Suzanne (and the group).

I did some studying of IgA while I was away, and I learned that in
order for the body to form secretory IgA and transport it into the
lumen of the gut, cysteine is required. As you know, so far I
haven't seen evidence that you are depleted in glutathione (and
hence, in cysteine), but I'm now wondering if this is a possibility
to explain the low secretory IgA levels that show up in the saliva
tests of so many PWCs. I'm wondering if anyone on the list has had
both their serum IgA (in the blood) and their secretory IgA (in the
saliva) measured. If the serum IgA is in the normal range, and the
secretory IgA is below normal, perhaps a lack of enough cysteine
could explain it.

Rich


> Does anyone know how to raise Secretory IGA? Mine is consistanly
low, very low on my ASI tests and I think this is why I have so many
bowel infections. Any ideas? What makes it go low in the first
place? MIne is 5 and normal is something like 25-60....
>
> Thanks,
> Suzanne
>
>



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